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Walter Malorni
Researcher at Istituto Superiore di Sanità
Publications - 371
Citations - 39681
Walter Malorni is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 69, co-authored 363 publications receiving 33990 citations.
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Journal ArticleDOI
Interaction of Clostridium difficile toxin A with cultured cells: cytoskeletal changes and nuclear polarization.
Carla Fiorentini,Walter Malorni,Silvia Paradisi,Marina Giuliano,Paola Mastrantonio,Gianfranco Donelli +5 more
TL;DR: The results suggest the involvement of an acidic compartment and the action of a serine protease in toxin A-induced cytopathic effect, which may be necessary for the nuclear displacement of cells.
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Efficacy of trimetazidine on functional capacity in symptomatic patients with stable exertional angina — The VASCO-angina study ☆
Cristiana Vitale,Ilaria Spoletini,Walter Malorni,Pasquale Perrone-Filardi,Maurizio Volterrani,Giuseppe M.C. Rosano +5 more
TL;DR: The VASCO-angina gives evidence for the efficacy and tolerability of standard and high dose of TMZ in improving effort-induced myocardial ischemia and functional capacity in patients with chronic stable angina receiving background beta-blockers.
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The cytoskeleton as a target in quinone toxicity.
TL;DR: It is demonstrated that alkylating and redox cycling quinones cause similar structural and biochemical modifications of the cytoskeleton by means of different mechanisms, namely alkylation and oxidation of critical sulfhydryl groups.
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Cell sex determines anoikis resistance in vascular smooth muscle cells
Elisabetta Straface,Rosa Vona,Lucrezia Gambardella,Barbara Ascione,Maria Marino,Paola Bulzomi,Silvia Canu,Rita Coinu,Giuseppe M.C. Rosano,Walter Malorni,Flavia Franconi +10 more
TL;DR: Female rats show adhesion‐associated resistance to apoptosis, the so called anoikis resistance, apparently due to a more adhering phenotype, characterized by a well organized actin microfilament cytoskeleton and to an increased phosphorylated focal adhesion kinase.
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Role of alpha-synuclein in autophagy modulation of primary human T lymphocytes
Tania Colasanti,Marta Vomero,Cristiano Alessandri,Cristiana Barbati,Angela Maselli,Cristina Camperio,Fabrizio Conti,Antonella Tinari,Carmelo Carlo-Stella,Loretta Tuosto,D Benincasa,Guido Valesini,Walter Malorni,Marina Pierdominici,Elena Ortona +14 more
TL;DR: It is suggested that α-synuclein could be considered as an autophagy-related marker of peripheral blood lymphocytes, potentially suitable for use in the clinical practice.