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Walter Malorni
Researcher at Istituto Superiore di Sanità
Publications - 371
Citations - 39681
Walter Malorni is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 69, co-authored 363 publications receiving 33990 citations.
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Nutrition and human health from a sex–gender perspective
TL;DR: This article will review some of the differences underlying the impact of food components on the risk of developing diseases from a sex-gender perspective.
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Flow cytometric analysis of the early phases of apoptosis by cellular and nuclear techniques.
Cristiano Ferlini,Silvia Di Cesare,Gabriella Rainaldi,Walter Malorni,Paola Samoggia,Roberto Biselli,Andrea Fattorossi +6 more
TL;DR: Ch chromatin texture is altered in early apoptosis and affects DNA stainability, suggesting that complex alterations in mitochondrial structure and functioning occur in the early stages of apoptosis.
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Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high-fat-diet-fed mice
Andrea Armani,Francesca Cinti,Vincenzo Marzolla,James Morgan,Greg A. Cranston,Antonella Antelmi,Giulia Carpinelli,Rossella Canese,Uberto Pagotto,Carmelo Quarta,Walter Malorni,Paola Matarrese,Matteo Marconi,Andrea Fabbri,Giuseppe M.C. Rosano,Saverio Cinti,Morag J. Young,Massimiliano Caprio +17 more
TL;DR: It is shown that adipocyte MR regulates brown remodeling of WAT through a modulation of autophagy, which provides a rationale for the use of MR antagonists to prevent the adverse metabolic consequences of adipocyte dysfunction in high‐fat‐diet‐fed mice.
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Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation.
Tina Garofalo,Paola Matarrese,Valeria Manganelli,Matteo Marconi,Antonella Tinari,Lucrezia Gambardella,Alberto Faggioni,Roberta Misasi,Maurizio Sorice,Walter Malorni +9 more
TL;DR: It is hypothesized that MAM raft-like microdomains could be pivotal in the initial organelle scrambling activity that finally leads to the formation of autophagosome.
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Peroxynitrite induces senescence and apoptosis of red blood cells through the activation of aspartyl and cysteinyl proteases
Paola Matarrese,Elisabetta Straface,Donatella Pietraforte,Lucrezia Gambardella,Rosa Vona,Alessandro Maccaglia,Maurizio Minetti,Walter Malorni +7 more
TL;DR: Results indicate that peroxynitrite, a milestone of redox‐mediated damage in human pathology, can hijack human RBC toward senescence and apoptosis by a mechanism involving both cysteinyl and aspartyl proteases.