Walter Malorni

TL;DR: Results indicate that a sort of “gender memory” can be conserved in VMSC in primary culture, and a gender difference was detected in both basal and irradiated VSMC.

TL;DR: In a series of experiments, pretreatment of rats with indomethacin prevented apoptotic death typically produced by gp120 in the neocortex of rat suggesting that enhancement of COX-2 expression may be involved in the mechanisms of apoptosis yielded by the HIV-1 coat protein.

TL;DR: The mechanisms underlying the formation of the leukocyte Uropod, the role of cytoskeleton in defining its structure and function, and the involvement of the uropod in the complex interplay between immune cells are reviewed.

TL;DR: The mechanisms underlying the pro‐apoptotic activity exerted by gliadin‐derived peptides in Caco‐2 intestinal cells, a cell line which retains many morphological and enzymatic features typical of normal human enterocytes, are investigated and it is found that digested peptides from wheat gliadins induce apoptosis by the CD95/Fas apoptotic pathway.

TL;DR: The data suggest that anti-ERα autoantibodies interfere with T lymphocyte homeostasis and are significantly associated with lupus disease activity.