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Warren M. Zapol
Researcher at Harvard University
Publications - 423
Citations - 26610
Warren M. Zapol is an academic researcher from Harvard University. The author has contributed to research in topics: Nitric oxide & Pulmonary hypertension. The author has an hindex of 81, co-authored 418 publications receiving 25338 citations. Previous affiliations of Warren M. Zapol include Brigham and Women's Hospital & University of British Columbia.
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Journal ArticleDOI
Inhaled Nitric Oxide for the Adult Respiratory Distress Syndrome
TL;DR: Inhalation of nitric oxide by patients with severe adult respiratory distress syndrome reduces the pulmonary-artery pressure and increases arterial oxygenation by improving the matching of ventilation with perfusion, without producing systemic vasodilation.
Journal ArticleDOI
Extracorporeal membrane oxygenation in severe acute respiratory failure. A randomized prospective study.
Warren M. Zapol,Michael T. Snider,J. D. Hill,R. J. Fallat,Robert H. Bartlett,L. H. Edmunds,A. H. Morris,E C Peirce nd,A. N. Thomas,H. J. Proctor,P. A. Drinker,P. C. Pratt,A. Bagniewski,R. G. Miller +13 more
TL;DR: It is concluded that ECMO can support respiratory gas exchange but did not increase the probability of long-term survival in patients with severe ARF.
Journal ArticleDOI
Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction.
TL;DR: Breathing 80 ppm NO for 3 hours did not increase either methemoglobin or extravascular lung water levels or modify lung histology compared with those in control lambs.
Journal ArticleDOI
Inhaled nitric oxide in persistent pulmonary hypertension of the newborn
TL;DR: Low levels of inhaled NO have an important role in the reversal of hypoxaemia due to PPHN, and this treatment rapidly and significantly increased preductal oxygen saturation and oxygen tensions.
Journal ArticleDOI
Inhaled Nitric Oxide and Persistent Pulmonary Hypertension of the Newborn
Jesse D. Roberts,Jeffrey R. Fineman,Frederick C. Morin,Philip W. Shaul,Stephen Rimar,Michael D. Schreiber,Richard A. Polin,Maurice S. Zwass,Michael M. Zayek,Ian Gross,Michael A. Heymann,Warren M. Zapol,Kajori G. Thusu,Thomas M. Zellers,Mark E. Wylam,Alan M. Zaslavsky +15 more
TL;DR: Inhaled nitric oxide improves systemic oxygenation in infants with persistent pulmonary hypertension and may reduce the need for more invasive treatments.