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William Borkowsky
Researcher at New York University
Publications - 215
Citations - 10325
William Borkowsky is an academic researcher from New York University. The author has contributed to research in topics: Viral load & Vaccination. The author has an hindex of 51, co-authored 214 publications receiving 9992 citations. Previous affiliations of William Borkowsky include Cornell University & State University of New York Upstate Medical University.
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Journal ArticleDOI
Development and application of a multiplex assay for the simultaneous measurement of antibody responses elicited by common childhood vaccines.
Hannah L. Itell,Erin McGuire,Petronella Muresan,Coleen K. Cunningham,Elizabeth J. McFarland,William Borkowsky,Sallie R. Permar,Genevieve G. Fouda +7 more
TL;DR: A reliable, high-throughput technique that requires minimal sample volume to measure multiple antibody concentrations concurrently, and is an efficient alternative to ELISAs for the measurement of vaccine-elicited antibody responses in large cohorts is developed.
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The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children.
Paolo Palma,Caroline Foster,Pablo Rojo,Paola Zangari,Paola Zangari,Andrew J. Yates,Nicola Cotugno,Nicola Cotugno,Nigel Klein,Katherine Luzuriaga,Savita Pahwa,Eleni Nastouli,Diana M. Gibb,William Borkowsky,Stefania Bernardi,Vincent Calvez,Emma Concetta Manno,Emma Concetta Manno,Nadia Mora,Alexandra Compagnucci,Britta Wahren,María Ángeles Muñoz-Fernández,A. De Rossi,Jintanat Ananworanich,Deenan Pillay,Carlo Giaquinto,Paolo Rossi,Paolo Rossi +27 more
TL;DR: The goal of EPIICAL is the establishment of an international collaboration to develop a predictive platform to select promising HIV therapeutic vaccine candidates, leading to prioritisation or deprioritisation of novel immunotherapeutic strategies.
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Abnormal newborn screens and acylcarnitines in HIV-exposed and ARV-exposed infants.
Brian Kirmse,Charlotte V. Hobbs,Inga Peter,Bryan LaPlante,Michele Caggana,Karen Kloke,Kimiyo Raymond,Marshall L. Summar,William Borkowsky +8 more
TL;DR: A higher proportion of positive metabolic screens in HIV screen–positive neonates suggests that HIV or ARV exposure is associated with dysfunctional intermediary metabolism in newborns, suggesting that ARV may perturb normal fatty acid oxidation in some infants.
Journal Article
The Proliferative Response of Human Lymphocytes to Antigen Is Suppressed Preferentially by Lymphocytes Precultured with the same Antigen
TL;DR: Human blood lymphocytes activated in vitro with antigen to which the donor is reactive are capable of suppressing the secondary proliferative response of autochthonous fresh cells to antigen, both antigen-specific and antigen-nonspecific suppression.
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HIV-Infected Children Have Elevated Levels of PD-1+ Memory CD4 T Cells With Low Proliferative Capacity and High Inflammatory Cytokine Effector Functions.
Julia Foldi,Lina Kozhaya,Bret McCarty,Mussa Mwamzuka,Fatma Marshed,Tiina Ilmet,Max Kilberg,Adam Kravietz,Aabid Ahmed,William Borkowsky,Derya Unutmaz,Alka Khaitan +11 more
TL;DR: Differences in PD-1+ CD4 T-cell memory phenotype and response to blockade between HIV-infected children and adults are highlighted, with implications for potential immune checkpoint therapies.