W
William T. Shi
Researcher at Philips
Publications - 87
Citations - 1651
William T. Shi is an academic researcher from Philips. The author has contributed to research in topics: Ultrasound & Microbubbles. The author has an hindex of 20, co-authored 87 publications receiving 1566 citations.
Papers
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Journal ArticleDOI
Characterization of ultrasound contrast microbubbles using in vitro experiments and viscous and viscoelastic interface models for encapsulation.
TL;DR: Zero-thickness interface models are developed to describe the encapsulation of microbubble contrast agents with rheological parameters such as surface tension, surface Dilatational viscosity, and surface dilatational elasticity to characterize a widely used microbubbles based ultrasound contrast agent.
Journal ArticleDOI
Oil-filled polymer microcapsules for ultrasound-mediated delivery of lipophilic drugs.
Klazina Kooiman,Marcel Rene Bohmer,M. Emmer,Hendrik J. Vos,Ceciel Chlon,William T. Shi,Christopher S. Hall,Suzanne H.P.M. de Winter,Karin Schroën,Michel Versluis,Nico de Jong,Nico de Jong,Annemieke van Wamel +12 more
TL;DR: The partially oil-filled microcapsules with high drug loads and well-defined acoustic activation thresholds have great potential for ultrasound-triggered local delivery of lipophilic drugs under ultrasound image-guidance.
Journal ArticleDOI
Material characterization of the encapsulation of an ultrasound contrast microbubble and its subharmonic response: Strain-softening interfacial elasticity model
Shirshendu Paul,Amit Katiyar,Kausik Sarkar,Dhiman Chatterjee,William T. Shi,Flemming Forsberg +5 more
TL;DR: The nonlinear strain softening included in the proposed elastic models of the encapsulation improves their ability to predict subharmonic response, and they predict the threshold excitation for the initiation of sub Harmonic response and its subsequent saturation.
Journal ArticleDOI
Tissue-specific US contrast agent for evaluation of hepatic and splenic parenchyma
TL;DR: The characteristic appearance of acoustic emission signals provides a distinctive method of visualizing normal hepatic tissues and substantially improves the detectability of hepatic tumors.
Tissue-Specific US Contrast Agent for Evaluation of Hepatic and Splenic
TL;DR: In this article, color Doppler imaging (CDI) was performed in a gel phantom, with SHU 563A microbubbles in stationary suspension, which demonstrated a random mosaic color pattern in spite of the lack of flow.