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Wolfgang Otto
Researcher at University of Regensburg
Publications - 150
Citations - 3634
Wolfgang Otto is an academic researcher from University of Regensburg. The author has contributed to research in topics: Bladder cancer & Cystectomy. The author has an hindex of 29, co-authored 142 publications receiving 3071 citations. Previous affiliations of Wolfgang Otto include McGill University Health Centre & Saint Joseph's University.
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Journal ArticleDOI
Early Versus Deferred Cystectomy for Initial High-Risk pT1G3 Urothelial Carcinoma of the Bladder: Do Risk Factors Define Feasibility of Bladder-Sparing Approach?
Stefan Denzinger,Hans-Martin Fritsche,Wolfgang Otto,Andreas Blana,W.F. Wieland,Maximilian Burger +5 more
TL;DR: Early as opposed to deferred CX seems to prolong the cancer-specific survival rate in high-risk pT1G3 BC, and patients with CIS should be considered for early CX owing to reduced cancer- specific survival in case of deferred CZ.
Journal ArticleDOI
Characteristics and outcomes of patients with clinical T1 grade 3 urothelial carcinoma treated with radical cystectomy: results from an international cohort.
Hans-Martin Fritsche,Maximilian Burger,Robert S. Svatek,Claudio Jeldres,Pierre I. Karakiewicz,Giacomo Novara,Eila C. Skinner,Stefan Denzinger,Yves Fradet,Hendrik Isbarn,Patrick J. Bastian,Patrick J. Bastian,Bjoern G. Volkmer,Francesco Montorsi,Wassim Kassouf,Derya Tilki,Wolfgang Otto,Umberto Capitanio,Jonathan I. Izawa,Vincenzo Ficarra,Seth P. Lerner,Arthur I. Sagalowsky,Mark P. Schoenberg,Ashish M. Kamat,Colin P.N. Dinney,Yair Lotan,Shahrokh F. Shariat +26 more
TL;DR: Almost half of the patients treated with RC without neoadjuvant chemotherapy for clinical T1G3 UCB are upstaged to muscle-invasive UCB, which supports the inadequacy of clinical decision making based on current treatment paradigms and staging tools.
Journal ArticleDOI
ICUD-EAU International Consultation on Bladder Cancer 2012: Non-muscle-invasive urothelial carcinoma of the bladder.
Maximilian Burger,Willem Oosterlinck,Badrinath R. Konety,Sam S. Chang,Sigurdur Gudjonsson,Raj S. Pruthi,Mark S. Soloway,Eduardo Solsona,Paul Sved,Marko Babjuk,Maurizio Brausi,Christopher Cheng,Eva Comperat,Colin P.N. Dinney,Wolfgang Otto,Jay B. Shah,Joachim Thürof,J. Alfred Witjes +17 more
TL;DR: A summary of the Second International Consultation on Bladder Cancer recommendations on the diagnosis and treatment options for non-muscle-invasive urothelial cancer of the bladder (NMIBC) using an evidence-based approach is presented.
Journal ArticleDOI
Gender differences in radical nephroureterectomy for upper tract urothelial carcinoma.
Shahrokh F. Shariat,Ricardo L. Favaretto,Amit Gupta,Hans-Martin Fritsche,Kazumasa Matsumoto,Wassim Kassouf,Thomas J. Walton,Stefan Tritschler,Shiro Baba,Kazuhito Matsushita,Patrick J. Bastian,Juan Ignacio Martínez-Salamanca,Christian Seitz,Armin Pycha,Wolfgang Otto,Pierre I. Karakiewicz,Vincenzo Ficarra,Giacomo Novara +17 more
TL;DR: Evaluated the prognostic value of gender in an international cohort of patients treated with radical nephroureterectomy for upper tract urothelial carcinoma (UTUC) and found no difference in histopathologic features and outcomes between men and women treated with RNU for UTUC.
Journal ArticleDOI
The Tumor Immune Microenvironment Drives a Prognostic Relevance that Correlates with Bladder Cancer Subtypes
Carolin Pfannstiel,Pamela L. Strissel,Katherine B. Chiappinelli,Danijel Sikic,Sven Wach,Ralph M. Wirtz,Adrian Wullweber,Helge Taubert,Johannes Breyer,Wolfgang Otto,Thomas Stefan Worst,Maximilian Burger,Bernd Wullich,Christian Bolenz,Nicole Fuhrich,Carol Geppert,Veronika Weyerer,Robert Stoehr,Simone Bertz,Bastian Keck,Franziska Erlmeier,Philipp Erben,Arndt Hartmann,Reiner Strick,Markus Eckstein +24 more
TL;DR: It is demonstrated that the quantity and spatial distribution of stromal tumor-infiltrating lymphocytes (sTIL) within the tumor immune microenvironment (TIME) predict stages of tumor inflammation, subtypes, and patient survival and correlate with expression of immune checkpoints in an analysis of 542 patients with MIBC.