C
Christopher Cheng
Researcher at Singapore General Hospital
Publications - 108
Citations - 3162
Christopher Cheng is an academic researcher from Singapore General Hospital. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 27, co-authored 108 publications receiving 2924 citations. Previous affiliations of Christopher Cheng include University of Tsukuba & National University of Singapore.
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Journal ArticleDOI
Changing demography of prostate cancer in Asia.
Hong Gee Sim,Christopher Cheng +1 more
TL;DR: With gradual Westernisation, many Asian countries may be losing their cultural protective factors and acquiring high- risk ones, and a better understanding of how these factors interact to cause prostate cancer through further studies with a multi-ethnic perspective will facilitate appropriate public health strategies to minimise high-risk factors and maintain Protective factors and keep prostate cancer at bay.
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Prognostic Factors and Predictive Models in Renal Cell Carcinoma: A Contemporary Review
Maxine Sun,Shahrokh F. Shariat,Christopher Cheng,Vincenzo Ficarra,Masaru Murai,Stéphane Oudard,Allan J. Pantuck,Richard Zigeuner,Pierre I. Karakiewicz +8 more
TL;DR: Several prognostic factors can help discriminate between favourable and unfavourable RCC phenotypes, and several clinical, pathologic, and biologic markers have been tested and validated and they are used in predictive and prognostic models.
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A prospective randomized study comparing monopolar and bipolar transurethral resection of prostate using transurethral resection in saline (TURIS) system.
TL;DR: Bipolar T URP using the TURIS system is clinically comparable to monopolar TURP at 1 yr with an improved safety profile and the IPSS and Q(max) improvements were comparable between the two groups at 12 mo of follow-up.
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ICUD-EAU International Consultation on Bladder Cancer 2012: Non-muscle-invasive urothelial carcinoma of the bladder.
Maximilian Burger,Willem Oosterlinck,Badrinath R. Konety,Sam S. Chang,Sigurdur Gudjonsson,Raj S. Pruthi,Mark S. Soloway,Eduardo Solsona,Paul Sved,Marko Babjuk,Maurizio Brausi,Christopher Cheng,Eva Comperat,Colin P.N. Dinney,Wolfgang Otto,Jay B. Shah,Joachim Thürof,J. Alfred Witjes +17 more
TL;DR: A summary of the Second International Consultation on Bladder Cancer recommendations on the diagnosis and treatment options for non-muscle-invasive urothelial cancer of the bladder (NMIBC) using an evidence-based approach is presented.
Journal ArticleDOI
Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2.
Lian Dee Ler,Sujoy Ghosh,Xiaoran Chai,Aye Aye Thike,Hong Lee Heng,Ee Yan Siew,Sucharita Dey,Liang Kai Koh,Jing Quan Lim,Weng Khong Lim,Swe Swe Myint,Jia Liang Loh,Pauline Ong,Xin Xiu Sam,Dachuan Huang,Tony Kiat Hon Lim,Puay Hoon Tan,Sanjanaa Nagarajan,Christopher Cheng,Henry Ho,Lay Guat Ng,John Shyi Peng Yuen,Po-Hung Lin,Cheng-Keng Chuang,Ying-Hsu Chang,Wen-Hui Weng,Steven G. Rozen,Patrick Tan,Caretha L. Creasy,See-Tong Pang,Michael T. McCabe,Song Ling Poon,Bin Tean Teh +32 more
TL;DR: This study demonstrates that inactivating mutations of KDM6A, which are common in urothelial bladder carcinoma, are potentially targetable by inhibiting EZH2 and small-molecule inhibitors of EZh2 were effective against KDM 6A-null bladder cancer in multiple mouse models.