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Xiaoxia Wang
Researcher at Peking University
Publications - 50
Citations - 1754
Xiaoxia Wang is an academic researcher from Peking University. The author has contributed to research in topics: Small interfering RNA & Gene silencing. The author has an hindex of 23, co-authored 46 publications receiving 1194 citations.
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Journal ArticleDOI
Long non-coding RNA ANRIL regulates inflammatory responses as a novel component of NF-κB pathway.
Xiao Zhou,Xiaorui Han,Ann Wittfeldt,Jingzhi Sun,Chu-Jun Liu,Xiaoxia Wang,Li-Ming Gan,Huiqing Cao,Zicai Liang +8 more
TL;DR: The newly identified TNF-α-NF-κB-ANRIL/YY1-IL6/8 pathway enhances understanding of the etiology of CAD and provides potential therapeutic target for treatment of CAD.
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A circulating miRNA signature as a diagnostic biomarker for non-invasive early detection of breast cancer
Lei Zhang,Ye Xu,Xingyu Jin,Zengwu Wang,Yidi Wu,Deyao Zhao,Gang Chen,Deyu Li,Xiaoxia Wang,Huiqing Cao,Yuntao Xie,Zicai Liang +11 more
TL;DR: The data demonstrate that the SdM-RT-PCR assay is an effective breast cancer profiling method that utilizes very small volumes and is compatible with Biobank and the identified 3-miRNA signature is a promising circulating biomarker for breast cancer diagnosis.
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Membrane-destabilizing ionizable lipid empowered imaging-guided siRNA delivery and cancer treatment
Shuai Guo,Kun Li,Bo Hu,Chunhui Li,Mengjie Zhang,Abid Hussain,Xiaoxia Wang,Qiang Cheng,Feng Yang,Kun Ge,Jinchao Zhang,Jin Chang,Xing-Jie Liang,Yuhua Weng,Yuanyu Huang +14 more
TL;DR: This study fabricated multifunctional ionizable lipid nanoparticles (iLNPs) for targeted delivery of siRNA and MRI contrast agent and revealed that GARP/siRNPs exhibited significantly higher cellular entry efficiency than GAP/siRNA iLNBP.
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The Promising Nanocarrier for Doxorubicin and siRNA Co-delivery by PDMAEMA-based Amphiphilic Nanomicelles.
Qiang Cheng,Lili Du,Lingwei Meng,Shangcong Han,Tuo Wei,Xiaoxia Wang,Yidi Wu,Xinyun Song,Junhui Zhou,Shuquan Zheng,Yuanyu Huang,Xing-Jie Liang,Huiqing Cao,Anjie Dong,Zicai Liang +14 more
TL;DR: PECD micelles have a potential ability as DOX and siRNA co-delivery carrier for cancer therapy, according to the results of drug release profile in acidic media, flow cytometry analysis and confocal images.
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Improved Nucleic Acid Therapy with Advanced Nanoscale Biotechnology
Yuhua Weng,Qianqian Huang,Chunhui Li,Yongfeng Yang,Xiaoxia Wang,Jie Yu,Yuanyu Huang,Xing-Jie Liang +7 more
TL;DR: The characteristics of different NA modalities are introduced and how advanced nanoscale biotechnology assists NA therapy is illustrated to illustrate how major barriers to the development of NA therapy will eventually be overcome in the near future.