Y
Yanan Zhao
Researcher at Rutgers Biomedical and Health Sciences
Publications - 67
Citations - 2141
Yanan Zhao is an academic researcher from Rutgers Biomedical and Health Sciences. The author has contributed to research in topics: Echinocandin & Micafungin. The author has an hindex of 22, co-authored 63 publications receiving 1728 citations. Previous affiliations of Yanan Zhao include Rutgers University & Seton Hall University.
Papers
More filters
Journal ArticleDOI
Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.
Kelley R. Healey,Yanan Zhao,Winder B. Perez,Shawn R. Lockhart,Jack D. Sobel,Dimitrios Farmakiotis,Dimitrios Farmakiotis,Dimitrios P. Kontoyiannis,Dominique Sanglard,Saad J. Taj-Aldeen,Barbara D. Alexander,Cristina Jiménez-Ortigosa,Erika Shor,David S. Perlin +13 more
TL;DR: It is demonstrated that a mutator phenotype caused by a mismatch repair defect is prevalent in C. glabrata clinical isolates, and it is anticipated that identifying MSH2 defects in infecting strains may influence the management of patients on antifungal drug therapy.
Journal ArticleDOI
Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris.
Milena Kordalewska,Annie Lee,Steven Park,Indira Berrio,Anuradha Chowdhary,Yanan Zhao,David S. Perlin +6 more
TL;DR: The data suggest that only isolates carrying mutations in FKS1 are echinocandin resistant and that routine in vitro testing of C. auris isolates for susceptibility to caspofungin by the broth microdilution method should be viewed cautiously or avoided.
Journal ArticleDOI
Rapid and Accurate Molecular Identification of the Emerging Multidrug-Resistant Pathogen Candida auris
Milena Kordalewska,Yanan Zhao,Shawn R. Lockhart,Anuradha Chowdhary,Indira Berrio,David S. Perlin +5 more
TL;DR: Fast, robust, easy-to-perform and interpret PCR and real-time PCR assays to identify C. auris and related species are presented and overcome the deficiencies of existing phenotypic tests.
Journal ArticleDOI
Update on Antifungal Drug Resistance
TL;DR: Understanding the mechanisms responsible for acquired resistance will facilitate development of better diagnostics and therapeutic strategies to overcome and prevent antifungal resistance.
Journal ArticleDOI
Multiplex Real-Time PCR Assay for Detection and Classification of Klebsiella pneumoniae Carbapenemase Gene (bla KPC) Variants
Liang Chen,José R. Mediavilla,Andrea Endimiani,Andrea Endimiani,Marnie E. Rosenthal,Yanan Zhao,Robert A. Bonomo,Barry N. Kreiswirth +7 more
TL;DR: The development of a multiplex real-time PCR assay using molecular beacons (MB-PCR) for rapid and accurate identification of bla KPC variants should be useful for understanding the ongoing evolution of carbapenem resistance in Gram-negative bacteria.