Y
Yanping Lin
Researcher at University of Pennsylvania
Publications - 2
Citations - 878
Yanping Lin is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Gene silencing & Innate immune system. The author has an hindex of 2, co-authored 2 publications receiving 561 citations.
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Journal ArticleDOI
Cytoplasmic chromatin triggers inflammation in senescence and cancer
Zhixun Dou,Kanad Ghosh,Maria Grazia Vizioli,Jiajun Zhu,Payel Sen,Kirk J. Wangensteen,Johayra Simithy,Yemin Lan,Yanping Lin,Zhuo Zhou,Brian C. Capell,Caiyue Xu,Mingang Xu,Julia E. Kieckhaefer,Tianying Jiang,Michal Shoshkes-Carmel,K M Ahasan Al Tanim,Glen N. Barber,John T. Seykora,Sarah E. Millar,Klaus H. Kaestner,Benjamin A. Garcia,Peter D. Adams,Peter D. Adams,Shelley L. Berger +24 more
TL;DR: It is shown that cytoplasmic chromatin activates the innate immunity cytosolic DNA-sensing cGAS–STING (cyclic GMP–AMP synthase linked to stimulator of interferon genes) pathway, leading both to short-term inflammation to restrain activated oncogenes and to chronic inflammation that associates with tissue destruction and cancer.
Journal ArticleDOI
The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants.
Janko Gospocic,Emily J. Shields,Karl M. Glastad,Yanping Lin,Clint A. Penick,Hua Yan,Alexander S. Mikheyev,Timothy A. Linksvayer,Benjamin A. Garcia,Shelley L. Berger,Jürgen Liebig,Danny Reinberg,Roberto Bonasio +12 more
TL;DR: It is proposed that corazonin, a neuropeptide homologous to the vertebrate gonadotropin-releasing hormone, is a central regulator of caste identity and behavior in social insects.