Y
Ying Sun
Researcher at Karolinska Institutet
Publications - 20
Citations - 1974
Ying Sun is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Glomerular basement membrane & Podocyte. The author has an hindex of 12, co-authored 15 publications receiving 1351 citations.
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Journal ArticleDOI
A molecular atlas of cell types and zonation in the brain vasculature
Michael Vanlandewijck,Michael Vanlandewijck,Liqun He,Maarj A. Andaloussi Mäe,Johanna Andrae,Koji Ando,Francesca Del Gaudio,Khayrun Nahar,Thibaud Lebouvier,Thibaud Lebouvier,Bàrbara Laviña,Leonor Gouveia,Ying Sun,Elisabeth Raschperger,Markus Räsänen,Yvette Zarb,Naoki Mochizuki,Annika Keller,Urban Lendahl,Christer Betsholtz,Christer Betsholtz +20 more
TL;DR: The transcriptional basis of the gradual phenotypic change along the arteriovenous axis is uncovered and unexpected cell type differences are revealed: a seamless continuum for endothelial cells versus a punctuated continuum for mural cells.
Journal ArticleDOI
Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types.
Liqun He,Michael Vanlandewijck,Michael Vanlandewijck,Maarja Andaloussi Mäe,Johanna Andrae,Koji Ando,Francesca Del Gaudio,Khayrun Nahar,Thibaud Lebouvier,Thibaud Lebouvier,Bàrbara Laviña,Leonor Gouveia,Ying Sun,Elisabeth Raschperger,Åsa Segerstolpe,Jianping Liu,Sonja Gustafsson,Markus Räsänen,Yvette Zarb,Naoki Mochizuki,Annika Keller,Urban Lendahl,Christer Betsholtz,Christer Betsholtz +23 more
TL;DR: The dataset constitutes a comprehensive molecular atlas of vascular and vessel-associated cell types in the mouse brain and lung, and as such provides a strong foundation for future studies of vascular development and diseases.
Journal ArticleDOI
Large-scale identification of genes implicated in kidney glomerulus development and function.
Minoru Takemoto,Liqun He,Jenny Norlin,Jaakko Patrakka,Zhijie Xiao,Tatiana V. Petrova,Cecilia Bondjers,Julia Asp,Elisabet Wallgard,Ying Sun,Tore Samuelsson,Petter Mostad,Samuel Lundin,Naoyuki Miura,Yoshikazu Sado,Kari Alitalo,Susan E. Quaggin,Karl Tryggvason,Christer Betsholtz +18 more
TL;DR: It is shown that Foxc2 controls the expression of a distinct set of podocyte genes involved in podocyte differentiation and glomerular basement membrane maturation, and surmise that studies on the other novel glomerulus‐enriched transcripts identified in this study will provide new insight intoglomerular development and pathomechanisms of disease.
Journal Article
Nephrin is involved in podocyte maturation but not survival during glomerular development. Commentary
M. Simons,Tobias B. Huber,S. C. Done,Minoru Takemoto,Liqun He,Ying Sun,Kjell Hultenby,Christer Betsholtz,Karl Tryggvason +8 more
TL;DR: In this paper, the authors found that nephrin is expressed late in the process of podocyte differentiation and is a locus for the formation of the foot process and physical integrity in vivo.
Journal ArticleDOI
Nephrin is involved in podocyte maturation but not survival during glomerular development
S. C. Done,Minoru Takemoto,Liqun He,Ying Sun,Kjell Hultenby,Christer Betsholtz,Karl Tryggvason +6 more
TL;DR: The results suggest that nephrin is expressed late in the process of podocyte differentiation and is a locus for the formation of SD and FP maintenance and physical integrity in vivo.