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Yong Sup Lee
Researcher at Kyung Hee University
Publications - 133
Citations - 2619
Yong Sup Lee is an academic researcher from Kyung Hee University. The author has contributed to research in topics: Chemistry & Dopamine transporter. The author has an hindex of 21, co-authored 123 publications receiving 2064 citations. Previous affiliations of Yong Sup Lee include Yonsei University & Islamia University.
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Antimicrobial natural products: an update on future antibiotic drug candidates
Muhammad Saleem,Mamona Nazir,Muhammad Ali,Hidayat Hussain,Yong Sup Lee,Naheed Riaz,Abdul Jabbar +6 more
TL;DR: This review will describe only those with potentially useful antimicrobial activity, viz. with MICs in the range 0.02-10 microg mL(-1); a total of 145 compounds from 13 structural classes are discussed, and over 100 references are cited.
Journal ArticleDOI
Antimicrobial Natural Products: An Update on Future Antibiotic Drug Candidates
Muhammad Saleem,Mamona Nazir,Muhammad Ali,Hidayat Hussain,Yong Sup Lee,Naheed Riaz,Abdul Jabbar +6 more
TL;DR: In this article, a review of 145 compounds from 13 structural classes with potential to lead to more effective and less toxic antimicrobial drugs is presented, and over 100 references are cited.
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The seed extract of Cassia obtusifolia ameliorates learning and memory impairments induced by scopolamine or transient cerebral hypoperfusion in mice.
Dong-Hyun Kim,Byung Hoon Yoon,Yong Won Kim,Seung-Joo Lee,Bum Young Shin,Ji Wook Jung,Hyoung Ja Kim,Yong Sup Lee,Jae Sue Choi,Sun Yeou Kim,Kyung-Tae Lee,Jong Hoon Ryu +11 more
TL;DR: It is suggested that COE attenuates memory impairment induced by scopolamine or 2VO and that these effects are mediated by enhancing the cholinergic nervous system via acetylcholinesterase inhibition.
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Sulfuretin isolated from heartwood of Rhus verniciflua inhibits LPS-induced inducible nitric oxide synthase, cyclooxygenase-2, and pro-inflammatory cytokines expression via the down-regulation of NF-κB in RAW 264.7 murine macrophage cells
Ji-Sun Shin,Young-Mi Park,Jung-Hye Choi,Hee-Juhn Park,Min Cheol Shin,Yong Sup Lee,Kyung-Tae Lee +6 more
TL;DR: The results suggest that the anti-inflammatory effect of sulfuretin in LPS-treated RAW 264.7 macrophages is associated with the suppression of NF-kappaB transcriptional activity via the inhibitory regulation of IKKbeta phosphorylation.
Journal ArticleDOI
New imidazo[2,1-b]thiazole derivatives: Synthesis, in vitro anticancer evaluation, and in silico studies
Jin-Hun Park,Mohammed I. El-Gamal,Mohammed I. El-Gamal,Mohammed I. El-Gamal,Yong Sup Lee,Chang-Hyun Oh,Chang-Hyun Oh +6 more
TL;DR: A series of 18 new imidazo[2,1-b]thiazole derivatives was synthesized and in vitro antiproliferative activities against A375P human melanoma cell line and NCI-60 cell line panel were tested.