Y
Yuan Liu
Researcher at Wuhan University
Publications - 9
Citations - 3041
Yuan Liu is an academic researcher from Wuhan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 6, co-authored 6 publications receiving 2108 citations.
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Journal ArticleDOI
Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals.
Yuan Liu,Zhi Ning,Yu Chen,Ming Guo,Yingle Liu,Nirmal Kumar Gali,Li Sun,Yusen Duan,Jing Cai,Dane Westerdahl,Xinjin Liu,Ke Xu,Kin Fai Ho,Haidong Kan,Qingyan Fu,Ke Lan +15 more
TL;DR: It is proposed that room ventilation, open space, sanitization of protective apparel, and proper use and disinfection of toilet areas can effectively limit the concentration of SARS-CoV-2 RNA in aerosols, although the infectivity of the virus RNA was not established in this study.
Journal ArticleDOI
Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients.
Yong Xiong,Yuan Liu,Liu Cao,Dehe Wang,Ming Guo,Ao Jiang,Dong Guo,Wenjia Hu,Jiayi Yang,Zhidong Tang,Honglong Wu,Yongquan Lin,Meiyuan Zhang,Qi Zhang,Mang Shi,Yingle Liu,Yu Zhou,Ke Lan,Yu Chen +18 more
TL;DR: The results reveal distinct host inflammatory cytokine profiles to SARS-CoV-2 infection in patients, and highlight the association between COVID-19 pathogenesis and excessive cytokine release such as CCL2/MCP-1, CXCL10/IP-10, CCL3/MIP-1A, and CCL4/Mip1B.
Journal ArticleDOI
ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens.
Tao Suo,Xinjin Liu,Jiangpeng Feng,Ming Guo,Wenjia Hu,Dong Guo,Hafiz Ullah,Yang Yang,Qiuhan Zhang,Xin Wang,Muhanmmad Sajid,Zhixiang Huang,Liping Deng,Tielong Chen,Fang Liu,Ke Xu,Yuan Liu,Qi Zhang,Yingle Liu,Yong Xiong,Guozhong Chen,Ke Lan,Yu Chen +22 more
TL;DR: Overall, ddPCR shows superiority for clinical diagnosis of SARS-CoV-2 to reduce the false negative reports, which could be a powerful complement to the RT-PCR.
Posted ContentDOI
Aerodynamic Characteristics and RNA Concentration of SARS-CoV-2 Aerosol in Wuhan Hospitals during COVID-19 Outbreak
Yuan Liu,Zhi Ning,Yu Chen,Ming Guo,Yingle Liu,Nirmal Kumar Gali,Li Sun,Yusen Duan,Jing Cai,Dane Westerdahl,Xinjin Liu,Kin Fai Ho,Haidong Kan,Qingyan Fu,Ke Lan +14 more
TL;DR: Room ventilation, open space, proper use and disinfection of toilet can effectively limit aerosol transmission of SARS-CoV-2, and effective sanitization is critical in minimizing aerosol transmitters.
Posted ContentDOI
ddPCR: a more sensitive and accurate tool for SARS-CoV-2 detection in low viral load specimens
Tao Suo,Xinjin Liu,Jiangpeng Feng,Ming Guo,Wenjia Hu,Dong Guo,Hafiz Ullah,Yang Yang,Qiuhan Zhang,Xin Wang,Muhanmmad Sajid,Zhixiang Huang,Liping Deng,Tielong Chen,Fang Liu,Ke Xu,Yuan Liu,Qi Zhang,Yingle Liu,Yong Xiong,Guozhong Chen,Ke Lan,Yu Chen +22 more
TL;DR: In this paper, an optimized droplet digital PCR (ddPCR) was used for detection of SARS-CoV-2, which showed that the limit of detection of ddPCR is significantly lower than that of RT-PCR.