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Yung-Chi Cheng

Researcher at Yale University

Publications -  834
Citations -  44358

Yung-Chi Cheng is an academic researcher from Yale University. The author has contributed to research in topics: Medicine & Virus. The author has an hindex of 87, co-authored 683 publications receiving 42508 citations. Previous affiliations of Yung-Chi Cheng include University of Georgia & Vion Pharmaceuticals, Inc..

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Canonical Wnt signaling works downstream of iron overload to prevent ferroptosis from damaging osteoblast differentiation.

TL;DR: In this article , the authors show that increased intracellular iron by ferric ammonium citrate mimicking the so-called non-transferrin bound iron concentrations leads to impaired osteoblast differentiation.
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The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine.

TL;DR: Hypoxia is an important factor that may potentiate the activity of l-OddC and β-d-2′,2′-difluorodeoxycytidine in several human tumor cell lines including HepG2, Hep3B, A673, Panc-1, and RKO.
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Induction of heme oxygenase-1 by traditional Chinese medicine formulation ISF-1 and its ingredients as a cytoprotective mechanism against oxidative stress.

TL;DR: The herbal formulation ISF-1 was capable of inducing HO-1 expression, in vitro and in vivo, offering a potential mechanism for post-stroke rehabilitation, and may shed light on the development of mechanism-defined therapies based on traditional herbal remedies.