Yupeng Qiu

TL;DR: The shape of RNA can promote the formation and coexistence of the diverse array of RNA-rich liquid compartments found in a single cell and support a model in which structure-based, RNA-RNA interactions promote assembly of distinct droplets and protein-driven, conformational dynamics of the RNA maintain this identity.

TL;DR: Characterization of nonpalpable breast lesions is improved by the addition of viscoelastic strain imaging parameters, and the differentiation of malignant and benign BI-RADS 4 or 5 tumors is especially evident with the use of the retardation time estimates, T(1).

TL;DR: A single-molecule fluorescence study of the dynamics of Rad51 filament formation and its disruption by SRS2 reveals an exquisite and highly specific mechanism by which Srs2 regulates the Rad51 filaments formation.

TL;DR: It is found that the specific secondary structure of a cyclin mRNA is required for it to assemble into distinct droplets and be excluded from other droplets containing functionally-unrelated mRNAs.

TL;DR: It is demonstrated that the monomeric Chd1 remodeler shifts DNA back and forth by dynamically alternating between different segments of the nucleosome, and proposed that active interplay of the ATPase motor with the regulatory domains may promote dynamic nucleosomes structures uniquely suited for histone exchange and chromatin reorganization during transcription.