Therese M. Gerbich

TL;DR: The shape of RNA can promote the formation and coexistence of the diverse array of RNA-rich liquid compartments found in a single cell and support a model in which structure-based, RNA-RNA interactions promote assembly of distinct droplets and protein-driven, conformational dynamics of the RNA maintain this identity.

TL;DR: A range of 'non-model model organisms' are highlighted as emerging systems for tackling questions across the whole spectrum of biology (and beyond), the opportunities and challenges, and the outlook for the future.

TL;DR: It is found that the specific secondary structure of a cyclin mRNA is required for it to assemble into distinct droplets and be excluded from other droplets containing functionally-unrelated mRNAs.

TL;DR: A novel live-cell LSFM method, lateral interference tilted excitation (LITE), in which a tilted light sheet illuminates the detection objective focal plane without a sterically limiting illumination scheme, which is compatible with any detection objective, including oil immersion, without an upper NA limit.

TL;DR: This study shows that phosphorylation of the RNA-binding protein Whi3 is used to regulate functionally distinct condensates important for cell polarity and nuclear division in multinucleate fungus Ashbya gossypii.