Z
Zhaoyong Li
Researcher at Hunan University
Publications - 40
Citations - 4847
Zhaoyong Li is an academic researcher from Hunan University. The author has contributed to research in topics: microRNA & Cellular differentiation. The author has an hindex of 18, co-authored 36 publications receiving 3784 citations. Previous affiliations of Zhaoyong Li include Chinese Academy of Sciences & University of Massachusetts Medical School.
Papers
More filters
Journal ArticleDOI
Exon-intron circular RNAs regulate transcription in the nucleus
Zhaoyong Li,Chuan Huang,Chun Bao,Liang Chen,Mei Lin,Xiaolin Wang,Guolin Zhong,Bin Yu,Wanchen Hu,Limin Dai,Pengfei Zhu,Zhaoxia Chang,Qingfa Wu,Yi Zhao,Ya Jia,Ping Xu,Huijie Liu,Ge Shan +17 more
TL;DR: A new role for circRNAs in regulating gene expression in the nucleus is revealed, in which EIciRNAs enhance the expression of their parental genes in cis, and a regulatory strategy for transcriptional control via specific RNA-RNA interaction between U1 snRNA and EICIRNAs is highlighted.
Journal ArticleDOI
Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation
Zhaoyong Li,Mohammad Q. Hassan,Mohammed Jafferji,Rami I. Aqeilan,Ramiro Garzon,Carlo M. Croce,Andre J. van Wijnen,Janet L. Stein,Gary S. Stein,Jane B. Lian +9 more
TL;DR: It is proposed that this mechanism prevents fibrosis and facilitates mineral deposition when miR-29b reaches peak levels and is a key regulator of development of the osteoblast phenotype by targeting anti-osteogenic factors and modulating bone extracellular matrix proteins.
Journal ArticleDOI
A microRNA signature for a BMP2-induced osteoblast lineage commitment program.
Zhaoyong Li,Mohammad Q. Hassan,Stefano Volinia,Andre J. van Wijnen,Janet L. Stein,Carlo M. Croce,Jane B. Lian,Gary S. Stein +7 more
TL;DR: The studies establish a mechanism for BMP morphogens to selectively induce a tissue-specific phenotype and suppress alternative lineages by down-regulating multiple miRNAs that constitute an osteogenic program, thereby releasing from inhibition pathway components required for cell lineage commitment.
Journal ArticleDOI
Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression
Zhaoyong Li,Huafeng Zhang +1 more
TL;DR: Recent findings related to the regulation of glucose, fatty acid and amino acid metabolism, their crosstalk, and relevant cancer therapy strategy are reviewed.
Journal ArticleDOI
miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells
Mohammad Q. Hassan,Yukiko Maeda,Hanna Taipaleenmaki,Weibing Zhang,Mohammad Jafferji,Jonathan A. R. Gordon,Zhaoyong Li,Carlo M. Croce,Andre J. van Wijnen,Janet L. Stein,Gary S. Stein,Jane B. Lian +11 more
TL;DR: In this paper, the authors show that miR-218 is induced during osteoblast differentiation and has potent osteogenic properties, which can promote commitment and differentiation of bone marrow stromal cells by activating a positive Wnt signaling loop.