Zheng Li

TL;DR: The Immunological Genome Project combines immunology and computational biology laboratories in an effort to establish a complete 'road map' of gene-expression and regulatory networks in all immune cells.

TL;DR: This study depicts a complex MOA of QSYQ on myocardial infarction, a cardiovascular disease-related multilevel compound-target-pathway network connecting main compounds to those DEGs supported by literature evidences and the pathways that are functionally enriched in ArrayTrack.

TL;DR: A new hybrid algorithm integrating ordinary differential equation models with dynamic Bayesian network analysis, called Differential Equation-based Local Dynamic Bayesian Network (DELDBN), was proposed and implemented for gene regulatory network inference and significantly improved the accuracy and sensitivity of network inference compared with other approaches.

TL;DR: The most widely tested corn hybrid, NB6016, had triple-stacked CB/ CRW/RR and RR (NB6016 RR) pairs grown together in 736 yield tests, and was higher yielding than the isogenic RR control in 77% of the tests, with an average yield advantage of 0.55 ± 0.81 tonnes/ha.

TL;DR: Modified causal inference included in CI-PMF outperformed existing causal inference with a higher AUC (area under receiver operating characteristic curve) score and greater precision and performed better than single modified causal inference in predicting therapeutic drug-disease associations.