F
Francis S. Kim
Researcher at Harvard University
Publications - 4
Citations - 1871
Francis S. Kim is an academic researcher from Harvard University. The author has contributed to research in topics: Haematopoiesis & Stem cell. The author has an hindex of 3, co-authored 4 publications receiving 1537 citations. Previous affiliations of Francis S. Kim include Joslin Diabetes Center.
Papers
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Journal ArticleDOI
The Immunological Genome Project: networks of gene expression in immune cells
Tracy Heng,Michio W. Painter,Kutlu G. Elpek,Veronika Lukacs-Kornek,Nora Mauermann,Shannon J. Turley,Daphne Koller,Francis S. Kim,Amy J. Wagers,Natasha Asinovski,Scott Davis,Marlys S. Fassett,Markus Feuerer,Daniel H.D. Gray,Sokol Haxhinasto,Jonathan A. Hill,Gordon Hyatt,Catherine Laplace,Kristen Leatherbee,Diane Mathis,Christophe Benoist,Radu Jianu,David H. Laidlaw,J Adam Best,Jamie Knell,Ananda W. Goldrath,Jessica Jarjoura,Joseph C. Sun,Yanan Zhu,Lewis L. Lanier,Ayla Ergun,Zheng Li,James J. Collins,Susan A. Shinton,Richard R. Hardy,Randall Friedline,Katelyn Sylvia,Joonsoo Kang +37 more
TL;DR: The Immunological Genome Project combines immunology and computational biology laboratories in an effort to establish a complete 'road map' of gene-expression and regulatory networks in all immune cells.
Journal ArticleDOI
The Transcription Factor EGR1 Controls Both the Proliferation and Localization of Hematopoietic Stem Cells
Irene M. Min,Giorgio Pietramaggiori,Francis S. Kim,Francis S. Kim,Emmanuelle Passegué,Kristen E. Stevenson,Amy J. Wagers,Amy J. Wagers +7 more
TL;DR: The ability of this single factor to regulate both proliferation and mobilization of HSCs suggests that EGR1 commands a genetic program that coordinates stem cell division and migration to maintain appropriate HSC number and function.
Journal ArticleDOI
Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells
Roi Gazit,Brian S. Garrison,Brian S. Garrison,Tata Nageswara Rao,Tata Nageswara Rao,Tal Shay,James C. Costello,Jeff Ericson,Francis S. Kim,Francis S. Kim,James J. Collins,James J. Collins,Aviv Regev,Aviv Regev,Amy J. Wagers,Amy J. Wagers,Amy J. Wagers,Derrick J. Rossi,Derrick J. Rossi +18 more
TL;DR: In this paper, the authors performed transcriptome analysis of stem cells and their proximal progenitors to improve the molecular understanding of HSCs and to identify genes involved in transcriptional regulation, including a group of putative transcriptional repressors.
Book ChapterDOI
Hematopoietic Stem Cells and Somatic Stem Cells
Kah Yong Tan,Kah Yong Tan,Francis S. Kim,Francis S. Kim,Amy J. Wagers,Amy J. Wagers,Shane R. Mayack,Shane R. Mayack +7 more
TL;DR: Though adult stem cells exist at a very low frequency in adult tissues, they serve a critical function in maintaining tissue homeostasis and generating replacement cells to repair tissues after injury.