Z
Ziyou Ren
Researcher at Northwestern University
Publications - 27
Citations - 1190
Ziyou Ren is an academic researcher from Northwestern University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 8, co-authored 18 publications receiving 653 citations.
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Journal ArticleDOI
Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.
Paul A. Reyfman,James M. Walter,Nikita Joshi,Kishore R. Anekalla,Alexandra C. McQuattie-Pimentel,Stephen Chiu,Ramiro Fernandez,Mahzad Akbarpour,Ching I. Chen,Ziyou Ren,Rohan Verma,Hiam Abdala-Valencia,Kiwon Nam,Monica Chi,SeungHye Han,Francisco J. Gonzalez-Gonzalez,Saul Soberanes,Satoshi Watanabe,Kinola J.N. Williams,Annette S. Flozak,Trevor T. Nicholson,Vince K. Morgan,Deborah R. Winter,Monique Hinchcliff,Cara L. Hrusch,Robert D. Guzy,Catherine A. Bonham,Anne I. Sperling,Remzi Bag,Robert B. Hamanaka,Gökhan M. Mutlu,Anjana Yeldandi,Stacy A. Marshall,Ali Shilatifard,Luís A. Nunes Amaral,Harris Perlman,Jacob I. Sznajder,A. Christine Argento,Colin T. Gillespie,Jane Dematte,Manu Jain,Benjamin D. Singer,Karen M. Ridge,Anna P. Lam,Ankit Bharat,Sangeeta Bhorade,Cara J. Gottardi,G. R. Scott Budinger,Alexander V. Misharin +48 more
TL;DR: The results support the feasibility of discovery-based approaches using next-generation sequencing technologies to identify signaling pathways for targeting in the development of personalized therapies for patients with pulmonary fibrosis.
Journal ArticleDOI
Hospitalization, inpatient burden and comorbidities associated with bullous pemphigoid in the U.S.A.
Ziyou Ren,Derek Y. Hsu,Joaquin Brieva,Nanette B. Silverberg,Sinead Langan,Jonathan I. Silverberg +5 more
TL;DR: Bullous pemphigoid is associated with significant disability and comorbid health disorders that may lead to or result from hospitalization, but little is known about the inpatient burden andComorbidities of BP.
Journal ArticleDOI
The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging.
Alexandra C. McQuattie-Pimentel,Ziyou Ren,Nikita Joshi,Satoshi Watanabe,Thomas Stoeger,Monica Chi,Ziyan Lu,Lango Sichizya,Raul Piseaux Aillon,Ching I. Chen,Saul Soberanes,Zhangying Chen,Paul A. Reyfman,James M. Walter,Kishore R. Anekalla,Jennifer M. Davis,Kathryn A. Helmin,Constance E. Runyan,Hiam Abdala-Valencia,Kiwon Nam,Angelo Y. Meliton,Deborah R. Winter,Richard I. Morimoto,Gökhan M. Mutlu,Ankit Bharat,Harris Perlman,Cara J. Gottardi,Karen M. Ridge,Navdeep S. Chandel,Jacob I. Sznajder,William E. Balch,Benjamin D. Singer,Alexander V. Misharin,G. R. Scott Budinger +33 more
TL;DR: In this article, the authors performed an integrated analysis of single-cell RNA-Seq data that revealed homogenous age-related changes in the alveolar macrophage transcriptome in humans and mice.
Journal ArticleDOI
Multidimensional Assessment of the Host Response in Mechanically Ventilated Patients with Suspected Pneumonia
James M. Walter,Ziyou Ren,Tyrone J. Yacoub,Paul A. Reyfman,Raj D. Shah,Hiam Abdala-Valencia,Kiwon Nam,Vince K. Morgan,Kishore R. Anekalla,Nikita Joshi,Alexandra C. McQuattie-Pimentel,Ching I. Chen,Monica Chi,SeungHye Han,Francisco J. Gonzalez-Gonzalez,Saul Soberanes,Raul Piseaux Aillon,Satoshi Watanabe,Kinola J.N. Williams,Ziyan Lu,Joseph Paonessa,Peter Hountras,Madonna Breganio,Nicole Borkowski,Helen K. Donnelly,Jonathan P. Allen,Luís A. Nunes Amaral,Ankit Bharat,Alexander V. Misharin,Neda Bagheri,Alan R. Hauser,G. R. Scott Budinger,Richard G. Wunderink +32 more
TL;DR: Alveolar neutrophilia has a high negative predictive value for bacterial pneumonia in critically ill patients with suspected infection and this novel approach may facilitate a longitudinal and multidimensional assessment of the host response to bacterial pneumonia.
Journal ArticleDOI
Association of serious infections with pemphigus and pemphigoid: analysis of the Nationwide Inpatient Sample.
TL;DR: PEMphigus and pemphigoid are blistering disorders associated with barrier disruption, immune dysregulation and use of immunosuppressing systemic therapy, all of which may predispose towards serious infections.