Center for Global Development

About: Center for Global Development is a nonprofit organization based out in Washington D.C., District of Columbia, United States. It is known for research contribution in the topics: Poverty & Population. The organization has 1472 authors who have published 3891 publications receiving 162325 citations.

Quantification of the Influenza Virus Load by Real-Time Polymerase Chain Reaction in Nasopharyngeal Swabs of Patients Treated with Oseltamivir

Abstract: Influenza A virus load was assessed by real-time polymerase chain reaction (PCR) in nasopharyngeal swabs of infected patients treated with oseltamivir. The mean pretreatment virus load was significantly lower in the 24 patients (group A) who initiated treatment within 24 h of the onset of symptoms than it was in the 26 patients (group B) who initiated treatment between 24 and 48 h (1.6x105 vs. 8.4x105 copies/600 ng of total RNA, P=.04); after 48 h of treatment, twice as many patients in group B still had a positive PCR result, compared with patients in group A (42.3% vs. 20.7%). These virological results support the clinical benefit provided by early therapeutic intervention of influenza illness.

Enzalutamide (ENZA) in combination with abiraterone acetate (AA) in bone metastatic castration resistant prostate cancer (mCRPC).

Abstract: 5000 Background: Co-targeting the androgen receptor (AR) and paracrine androgen biosynthesis in mCRPC may be more effective than either alone. This study aims to evaluate safety, pharmacokinetic (P...

Another Inconvenient Truth: A Carbon-Intensive South Faces Environmental Disaster, No Matter What the North Does

Abstract: This paper critically examines a view of global warming that is common among developing countries (the South) and many in the development community: Developed countries (the North) caused climate change, the North should address the problem by dramatically reducing its own carbon emissions, and the South should be left free to develop along a carbon-intensive path until it is much richer. Our results indicate that this view cannot withstand empirical scrutiny and is, in fact, dangerous for the South itself. The South's cumulative carbon emissions are already large enough to jeopardize climatic stability and its own future growth, regardless of Northern emissions. By implication, a fossil-fueled South will undermine its own development long before it reaches Northern income levels. Sustainable development will therefore require a dramatic shift toward clean energy in the South, beginning immediately, as well as rapid reduction of Northern emissions.