Showing papers by "Cranfield University published in 1998"

Market-Based Assets and Shareholder Value: A Framework for Analysis

Abstract: The authors develop a conceptual framework of the marketing–finance interface and discuss its implications for the theory and practice of marketing. The framework proposes that marketing is concern...

The European Soil Erosion Model (EUROSEM): A dynamic approach for predicting sediment transport from fields and small catchments.

Abstract: The European Soil Erosion Model (EUROSEM) is a dynamic distributed model, able to simulate sediment transport, erosion and deposition over the land surface by rill and interill processes in single storms for both individual fields and small catchments. Model output includes total runoff, total soil loss, the storm hydrograph and storm sediment graph. Compared with other erosion models, EUROSEM has explicit simulation of interill and rill flow; plant cover effects on interception and rainfall energy; rock fragment (stoniness) effects on infiltration, flow velocity and splash erosion; and changes in the shape and size of rill channels as a result of erosion and deposition. The transport capacity of runoff is modelled using relationships based on over 500 experimental observations of shallow surface flows. EUROSEM can be applied to smooth slope planes without rills, rilled surfaces and surfaces with furrows. Examples are given of model output and of the unique capabilities of dynamic erosion modelling in general. © 1998 John Wiley & Sons, Ltd.

The Nature, Social Organization and Promotion of Management Research: Towards Policy

Abstract: This paper argues for the distinctiveness of management research and develops a perspective concerning management research policy. It argues that the key defining characteristic of management research is its applied nature, and that its central concern should be ‘the general (engineering) problem of design’. Because a key goal of management research is to improve the relationship between theory and practice, a fundamental concern lies with its diverse nature and the consequential difficulty of integration of sub-disciplines, as well as with the issue of the relevance and the application of findings. As a policy paper, it aims to introduce a limited number of analytical frameworks in order to develop a policy position, thus helping frame the debate concerning the role of management research. Specifically, it achieves this, first by exploring the ontology of management research, examining its form, features, peculiarities and idiosyncrasies using Becher's conceptual schema for exploring the nature of disciplines; second by identifying a requisite form of social organization to support management research activity using the Gibbons et al. taxonomy of knowledge production systems; and finally, by identifying some conclusions, research policy implications, and suggesting a set of policy propositions concerning the conduct of management research.

The supply chain complexity triangle: Uncertainty generation in the supply chain

Abstract: Since the late 1950s it has been recognised that the systems used internally within supply chains can lead to oscillations in demand and inventory as orders pass through the system. The uncertainty generated by these oscillations can result in late deliveries, order cancellations and an increased reliance on inventory to buffer these effects. Despite the best efforts of organisations to stabilise the dynamics generated, industry still experiences a high degree of uncertainty from this source. The “supply chain complexity triangle” describes the interaction of deterministic chaos, parallel interactions and demand amplification. It provides a framework for understanding the generation of uncertainty within supply chains. The implications for supply chain strategy and manufacturing logistics are discussed.

Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence. Correlation with disease progression and dedifferentiation

Abstract: The maintenance of adult tissue architecture is largely dependent on the function of cadherins. E-cadherin is expressed in most epithelia, although it may be co-expressed with P-cadherin in basal layers of stratified epithelia. Adhesive function of cadherins relies on interactions with catenins. Many reports have characterized reduced expression of cadherins and catenins in tumors, including those of the gastrointestinal tract. This study aimed to characterize expression of E- and P-cadherins, and the catenins, in the progression of Barrett's esophagus to adenocarcinoma. Immunohistochemical analysis and Western blotting were performed on paraffin-embedded and fresh-frozen tissue using antisera to the selected cadherins and catenins. The results of this study have shown inappropriate expression of cadherins and catenins in neoplastic Barrett's mucosa. There was a significant reduction of E-cadherin expression as the Barrett's metaplasia-dysplasia-adenocarcinoma sequence progressed (P < 0.01). In contrast, P-cadherin, expressed in basal layers of squamous esophagus, was usually absent from Barrett's and dysplasia but was expressed in 17 of 24 carcinomas, especially at the advancing tumor edge. Reduced expression of catenins was also seen, but in some specimens, immunoreactivity was observed in neoplastic nuclei, suggesting mediation of a nuclear function such as transcriptional regulation.

The Meanings of Career Revisited: Implications for Theory and Practice

Abstract: In everyday conversation, the term ‘career’ is generally understood to refer to the sequence of work-related experiences one has over the course of one's working lifetime. For many people, a career is distinct from a job, since it also conjures up images of steady, even logical, progression up organizational hierarchies. It is not simply about what one does for a living, but about what one has done, does now and might do in the future; the notion of career therefore embraces the dimension of time. In light of widespread organizational restructuring and economic uncertainty since the late 1980s, many of the taken-for-granted assumptions which have underpinned traditional notions of career, and in particular the organizational career, no longer seem valid. Both individuals and organizations are finding it increasingly difficult to conceptualize the idea of a logical, long-term sequence of work-related experiences; there is thus no longer a clear and mutual understanding of what the career means to both. This paper argues that individuals and organizations can meaningfully redefine the notion of career by reconsidering its broader, theoretical underpinnings.

Managerialism : something old, something borrowed, little new economic prescription versus effective organizational change in public agencies

Abstract: Of many managerialist panaceas, the most prevalent one today is the assertion that private sector practices will solve the public sector’s “self‐evident” inadequate performance. This managerialist view assumes hegemonic proportions in Anglo‐Saxon public sectors and largely goes unchallenged, notwithstanding serious reservations about the superiority of private managerial prerogatives one would draw from organization theory or, even, mainstream liberal economics, which is largely silent about the role of management and control in economic behaviour. It is a particular brand of economics that underscores the linking of public agency efficiency to managerial ability and performance. In neo‐institutional economics, “rent‐seeking” behaviour is attributed to civil servants, rather than corporate entrepreneurs, and from that ideological perspective of bureaucratic pathology flows a whole series of untested propositions culminating in the commercializing, corporatizing and privatizing rationales, now uncritically accepted by most bureaucrats themselves to be axiomatically true. The economistic underpinning of managerialism and its “New Functionalism” in organizational design hardly addresses the significant structural, cultural and behavioural changes necessary to bring about the rhetorical benefits said to flow from the application of managerialist solutions. Managerialism expects public managers to improve efficiency, reduce burdensome costs and enhance organizational performance in a competitive stakeholding situation. Managerialism largely ignores the administrative‐political environment which rewards risk‐averse behaviour which, in turn, militates against the very behavioural and organizational reforms managerialists putatively seek for the public sector.

A neutron diffraction investigation into the rhombohedral phases of the perovskite series

Abstract: Rietveld refinements using neutron powder profiles are reported for a series of samples (commonly known as PZT), with x ranging from to . Cation shifts, octahedral distortion and tilts are determined with varying composition across the ferroelectric rhombohedral regions, and , of the PZT phase diagram. These parameters are then used in conjunction with a simple Landau-Devonshire model to investigate the nature of the phase transition. It is found that the cation shifts, octahedral distortion and tilt angles decrease with increasing Ti content, but, surprisingly, the octahedral strain, as indicated by the rhombohedral angle, increases. This is in contrast to the case for all other known rhombohedral perovskites. Furthermore, the refined anisotropic displacement parameters of the cations are anomalous and cannot be accounted for by the average crystal structure. A model is presented in which a domain-type `local' structure is considered, containing `ordered' additional cation displacements, consistently with the reports of extra reflections observed in electron microscopy studies by Viehland et al, Dai et al and Ricote et al.

An integrated approach to municipal solid waste management

Abstract: A theoretical model has been developed for the management of municipal solid waste streams (MSW), taking into account their rates and compositions, as well as their adverse environmental impacts. The model identifies the optimal combination of technologies for the handling, treatment and disposal of MSW in a better economic and more environmentally sustainable way.

The histopathology of treated Barrett's esophagus: squamous reepithelialization after acid suppression and laser and photodynamic therapy.

Abstract: Columnar metaplasia of the lower esophageal epithelium (Barrett's esophagus) occurs in response to acid reflux, and its most important long-term complication is malignancy. In view of this, techniques are being explored for the eradication of Barrett's esophagus, and histopathologists will increasingly be required to assess response to these therapies in esophageal biopsy samples. The histopathologic features before and after treatment were studied in biopsy samples from 16 patients receiving omeprazole only, 10 treated by KTP laser photoablation, and five who underwent photodynamic therapy. All the treatment modalities resulted in histologic changes with at least partial squamous reepithelialization of the metaplastic columnar epithelium. The histologic findings suggest three main mechanisms for this: encroachment of adjacent squamous epithelium at the squamocolumnar junction, extension of epithelium from the submucosal gland duct to form squamous islands, and squamous metaplasia within the Barrett's columnar mucosa itself. The latter mechanism implies the existence of pluripotential stem cells within Barrett's mucosa. A relatively common finding was residual glandular mucosa, nonneoplastic and dysplastic, beneath squamous epithelium indicating the requirement for histologic confirmation of endoscopically suspected complete squamous reepithelialization with sufficiently deep biopsies.

Municipal solid waste: a prediction methodology for the generation rate and composition in the European Union countries and the United States of America

Abstract: The economically-viable and environmentally-acceptable disposal of municipal solid waste (MSW) is a major concern in many industrialised countries. The main problem facing policy makers in the waste management sector is how to predict the amount and the composition of MSW that is likely to be generated in the near future in order to devise the most appropriate treatment/disposal strategy. Published data on MSW arisings in European countries during the period 1980–1993 and those for the USA between 1960 and 1993 have been correlated with the corresponding figures for the gross domestic product (GDP) and population. The typical composition of MSW has been expressed in terms of the fraction of the total consumer expenditure on goods and products resulting in the generation of MSW, i.e. related total consumer expenditure (RTCE). A model linking RTCE to GDP has been developed and utilised to estimate the amounts of the individual fractions in the total MSW generated. The correlations permit highly-accurate predictions of the total amount of MSW arisings to be obtained both for European countries and the USA. Deviations between the predicted and measured values are, however, much lower in the case of the USA, because the corresponding model is based on data for a single country. Good matches between the predicted and measured figures for the individual fractions of the MSW also ensue. However, the model for predicting the individual fractions in the MSW for the European countries is based solely on information available for the UK.

Ecological determinants for germination and growth of some Aspergillus and Penicillium spp. from maize grain

Abstract: This study compared the effect of temperature (5–45 °C), water availability (water activity, aw; 0·995–0·75) and their interactions on the temporal rates of germination and mycelial growth of three mycotoxigenic strains of Aspergillus ochraceus and one isolate each of A flavus, A niger, Penicillium aurantiogriseum and P hordeiin vitro on a maize extract medium Germination was very rapid at >0·90 aw with an almost linear increase with time for all species However, at 30 °C for Penicillium spp There were also statistically significant differences between lag phases and germination rates for three different isolates of A ochraceus The Aspergillus spp also germinated faster than the Penicillium spp The temperature ×aw profiles for mycelial growth varied considerably between species, both in terms of rates (mm d–1) and tolerances Predictions of the effects of important environmental factors such as temperature, aw and their interactions on lag times to germination, germination rates and mycelial growth are important in the development of hurdle technology approaches to predicting fungal spoilage in agricultural and food products

Supplier‐Customer Relationships and Company Performance

Abstract: This paper describes preliminary research into the effect of different approaches to supply chain management on manufacturing company performance. Three generic models were developed to describe the ways in which manufacturers manage relationships with their major suppliers and major customers. A set of financial and non‐financial practice and performance measures was selected. Practice and performance data were collected from 74 U.K. manufacturers from the clothing and electronics industries. Data supplied by participating companies were used to test the appropriateness of the three generic models, and to investigate the ways in which their supplier‐customer relationships impact upon their performance.

Chaos Theory: Implications for Supply Chain Management

Abstract: Since the late 1950's it has been recognized that the systems used internally within supply chains can lead to oscillations in demand and inventory as orders pass through the system. The uncertainty generated can result in late deliveries, order cancellations and an increased reliance on inventory to buffer these effects. Despite the best efforts of organizations to stabilize the dynamics generated, industry still experiences a high degree of uncertainty. The failure to significantly reduce uncertainty through traditional approaches may in part be explained by chaos theory. This paper defines deterministic chaos and demonstrates that supply chains can display some of the key characteristics of chaotic systems, namely: chaos exhibits sensitivity to initial conditions; it has Islands of Stability; generates patterns; invalidates the reductionist view; and, undermines computer accuracy. The implications for the management and design of supply chains are discussed.

Demographics and leadership philosophy: exploring gender differences

Abstract: Leadership philosophy is explored through gender and other demographic characteristics in the Australian Public Service (APS), at the federal government level. Leadership philosophy is conceptualised as the leader’s attitudes, values and behaviour. Gender differences in characteristics of leaders (executives and middle managers) are examined in terms of strategic behaviour, management style, work‐related values, adoption of information technology, perceived organisational morale, family/work conflict and personal, work and family satisfaction. The gender differences are investigated using questionnaire responses from a sample of 750 respondents, of which 569 were male and 145 female. The APS findings are compared with a Cranfield study conducted in the UK’s National Health Service (NHS), where gender differences are explored in terms of management and strategic orientation. A sample of 515 chief executives, medical, clinical, HR and financial directors, chairpersons and other non‐executive directors, consists of 406 male and 108 female respondents. The APS study reveals that there are no significant gender differences in the majority of measured characteristics. Similarly in the NHS Trusts study, no significant gender differences are found in terms of management and strategic orientation. The conclusion reached is that other demographic characteristics are influential in forming leadership philosophies, namely job and organisational tenure and experience of senior management responsibilities, thus highlighting the importance of organisational demographics and their impact on leadership attitudes and practice.

Retail store image: a means‐end approach

Abstract: Retail store image has been shown to play an important role in store patronage, and it is widely accepted that psychological factors have a significant role in store image formation. Past research has often involved the measurement of tangible attributes, or links between store images and consumers’ self‐images. This study was undertaken to move to the next stage by exploring the link between perceived store image and the personal values which underlie behavioural choices. Fashion retailing was selected as an appropriate research domain because of the well‐established associations between clothing choice, personality, self concept, and personal values. Means‐end theory and laddering methodology were employed in interviews with 30 female respondents. The hedonic values of “enjoyment and happiness” and “quality of life” were found to be the terminal values most sought by consumers in association with store image. These were linked through the consequence “nice feeling” to the tangible attributes of “price”, “quality” and “reputation”. The study illustrates an application of means‐end methodology in a retail environment, and the results provide a platform for fashion store image and positioning strategies. Suggestions for further research are made.

Molecular Analysis of the Locus Responsible for Production of Plantaricin S, a Two-Peptide Bacteriocin Produced by Lactobacillus plantarum LPCO10

Abstract: A 4.5-kb region of chromosomal DNA carrying the locus responsible for the production of plantaricin S, a two-peptide bacteriocin produced by Lactobacillus plantarum LPCO10 (R. Jimenez-Diaz, J. L. Ruiz-Barba, D. P. Cathcart, H. Holo, I. F. Nes, K. H. Sletten, and P. J. Warner, Appl. Environ. Microbiol. 61:4459–4463, 1995), has been cloned, and the nucleotide sequence has been elucidated. Two genes, designated plsA and plsB and encoding peptides α and β, respectively, of plantaricin S, plus an open reading frame (ORF), ORF2, were found to be organized in an operon. Northern blot analysis showed that these genes are cotranscribed, giving a ca. 0.7-kb mRNA, whose transcription start point was determined by primer extension. Nucleotide sequences of plsA and plsB revealed that both genes are translated as bacteriocin precursors which include N-terminal leader sequences of the double-glycine type. The role of ORF2 is unknown at the moment, although it might be expected to encode an immunity protein of the type described for other bacteriocin operons. In addition, several other potential ORFs have been found, including some which may be responsible for the regulation of bacteriocin production. Two of them, ORF8 and ORF14, show strong homology with histidine protein kinase and response regulator genes, respectively, which have been found to be involved in the regulation of the production of other bacteriocins from lactic acid bacteria. A third ORF, ORF5, shows homology with gene agrB from Staphylococcus aureus, which is involved in the mechanism of regulation of the virulence phenotype in this species. Thus, an agr-like regulatory system for the production of plantaricin S is postulated.

Phosphorus losses from arable land in England

Abstract: Concentrations and annual loadings of molyhdate reactive P (MRP) and total (including particulate) P (TP) are reported from field drainage, catchment and erosion experiments in England. Annual losses through field drains and in catchment runoff were 0.037-0.74 kg MRP/ha and 0.37-2.64 kg TP/ha, but those in surface runoff from experimental plots measuring erosion were generally much greater (often > 3 kg MRP/ha and up to 32 kg TP/ha in a wet year). Amounts of TP in drainflow and catchment runoff depended upon factors influencing soil dispersibility, such as particle size distribution and calcium carbonate content. The results to date suggest that P losses in surface runoff and erosion from arable fields to water are best limited by: (a) maximizing crop cover, using minimal cultivation practices and where possible planting crop rows across rather than up and down the slope, (b) avoiding cultivation practices that result in dispersion of soil particles, and (c) avoiding application of P fertilizer to wet soils when rainfall is likely soon after application. Consideration should he given to maintaining field drains below peak efficiency to reduce subsurface P losses.