Institution
Dalhousie University
Education•Halifax, Nova Scotia, Canada•
About: Dalhousie University is a education organization based out in Halifax, Nova Scotia, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 25660 authors who have published 58465 publications receiving 2082403 citations. The organization is also known as: Dalhousie College & The Governors of Dalhousie College and University.
Papers published on a yearly basis
Papers
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TL;DR: It is confirmed that delays in communication and language development are apparent early in life in children with ASD, and developmental surveillance should include monitoring for delays in gesture, which may be among the earliest signs of ASD.
Abstract: It is well recognized that delayed ''first words'' is among the most common presenting symptoms of autistic spectrum disorders (ASD). However, data on earlier language and communication development in children with ASD are limited to retrospective reports from parents and from home videos. In this study, we prospectively collected parent report data on early communication and language development in 97 infant siblings of children with ASD and 49 low-risk controls. Parents completed the MacArthur Communicative Development InventoryYInfant Form at 12 and 18 months. Analysis compared 3 groups defined on the basis of diagnostic assessment at 24 months: (1) siblings with ASD (n = 15), (2) siblings not meeting diagnostic criteria for ASD (n = 82), and (3) low-risk controls, none of whom had ASD (n = 49). Children with ASD showed delays in early language and communication compared with non-ASD siblings and controls. At 12 months, the ASD group was reported to understand significantly fewer phrases and to produce fewer gestures. At 18 months, they showed delays in their understanding of phrases, comprehension and production of single words, and use of gestures. Siblings not diagnosed with ASD also used fewer play-related gestures at 18 months than low-risk controls, even when children with identified language delays were excluded. Overall, this prospective study confirms that delays in communication and language development are apparent early in life in children with ASD, and emphasizes that developmental surveillance should include monitoring for delays in gesture, which may be among the earliest signs of ASD. J Dev Behav Pediatr 27:69Y78, 2006. Index terms: autism, language, communication, gestures, infant behavior. The developmental challenges associated with autism arise from a unique constellation of features spanning social communication and language, and behavioral adaptation. The predominant features of autism-related developmental disorders (referred to collectively as the autistic spectrum of disorders; ASD) include qualitative impairments in both verbal and nonverbal communication. 1 In addition, receptive and expres-
457 citations
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TL;DR: The possibility that phylogenetically 'prepared' forms of defensive learning might serve as a basis for the study of anxiolytic agents is introduced.
456 citations
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TL;DR: It is concluded that a 150 mg/kg dose of MPTP can elicit apoptotic cell death in nigral dopaminergic neurons of the C57B1 mouse.
456 citations
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TL;DR: Investigation of relations of anxiety sensitivity and other theoretically relevant personality factors to Copper's four categories of substance use motivations as applied to teens' use of alcohol, cigarettes, and marijuana revealed that anxiety sensitivity moderated the relation between trait anxiety and coping motives for alcohol and cigarette use.
455 citations
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TL;DR: The effects of consumers and nutrients on diversity consistently depend on each other, and that the direction of their effects and peak diversity shift between sites of low and high productivity, suggesting human impacts on nutrient supply and food-web structure have strong and interdependent effects on species diversity and ecosystem functioning, and must therefore be managed together.
Abstract: A key question in ecology is which factors control species diversity in a community1, 2, 3. Two largely separate groups of ecologists have emphasized the importance of productivity or resource supply, and consumers or physical disturbance, respectively. These variables show unimodal relationships with diversity when manipulated in isolation4, 5, 6, 7, 8. Recent multivariate models9, 10, however, predict that these factors interact, such that the disturbance–diversity relationship depends on productivity, and vice versa. We tested these models in marine food webs, using field manipulations of nutrient resources and consumer pressure on rocky shores of contrasting productivity. Here we show that the effects of consumers and nutrients on diversity consistently depend on each other, and that the direction of their effects and peak diversity shift between sites of low and high productivity. Factorial meta-analysis of published experiments confirms these results across widely varying aquatic communities. Furthermore, our experiments demonstrate that these patterns extend to important ecosystem functions such as carbon storage and nitrogen retention. This suggests that human impacts on nutrient supply11 and food-web structure12, 13 have strong and interdependent effects on species diversity and ecosystem functioning, and must therefore be managed together.
453 citations
Authors
Showing all 25969 results
Name | H-index | Papers | Citations |
---|---|---|---|
Salim Yusuf | 231 | 1439 | 252912 |
Gordon H. Guyatt | 231 | 1620 | 228631 |
Michael Rutter | 188 | 676 | 151592 |
Mark E. Cooper | 158 | 1463 | 124887 |
Roberto Romero | 151 | 1516 | 108321 |
Rui Zhang | 151 | 2625 | 107917 |
Thomas J. Smith | 140 | 1775 | 113919 |
Dafna D. Gladman | 129 | 1036 | 75273 |
Marcello Tonelli | 128 | 701 | 115576 |
Shi Xue Dou | 122 | 2028 | 74031 |
J. R. Dahn | 120 | 832 | 66025 |
Scott Chapman | 118 | 579 | 46199 |
Kerry S. Courneya | 112 | 608 | 49504 |
Robert C. Haddon | 112 | 577 | 52712 |
Rodney J. Bartlett | 109 | 700 | 56154 |