I.M. Sechenov First Moscow State Medical University

About: I.M. Sechenov First Moscow State Medical University is a education organization based out in Moscow, Russia. It is known for research contribution in the topics: Medicine & Population. The organization has 7984 authors who have published 9355 publications receiving 68997 citations.

Interaction between Laser Light and Osteoblasts: Photobiomodulation as a Trend in the Management of Socket Bone Preservation-A Review.

Abstract: Bone defects are the main reason for aesthetic and functional disability, which negatively affect patient's quality of life. Particularly, after tooth extraction, the bone of the alveolar process resorbs, limiting the optimal prosthetic implant placement. One of the major pathophysiological events in slowly- or non-healing tissues is a blood supply deficiency, followed by a significant decrease in cellular energy amount. The literature shows that photons at the red and infrared wavelengths can interact with specific photoacceptors located within the cell. Through this mechanism, photobiomodulation (PBM) can modify cellular metabolism, by increasing mitochondrial ATP production. Here, we present a review of the literature on the effect of PBM on bone healing, for the management of socket preservation. A search strategy was developed in line with the PRISMA statement. The PubMed and Scholar electronic databases were consulted to search for in vivo studies, with restrictions on the year (<50 years-old), language (English), bone socket preservation, and PBM. Following the search strategy, we identified 269 records, which became 14, after duplicates were removed and titles, abstract and inclusion-, exclusion-criteria were screened. Additional articles identified were 3. Therefore, 17 articles were included in the synthesis. We highlight the osteoblast-light interaction, and the in vivo therapeutic tool of PBM is discussed.

A robust fuzzy optimisation for a multi-objective pharmaceutical supply chain network design problem considering reliability and delivery time

Abstract: Due to the emergency role of pharmaceutical supply chains, there has been rapid development of optimisation techniques as one of efficient tools to improve pharmaceutical supply chain network desig...

Headache yesterday in Russia: its prevalence and impact, and their application in estimating the national burden attributable to headache disorders

Abstract: Evaluation of the prevalence and impact of headache on the preceding day (“headache yesterday”; HY) is a new approach, allowing more precise estimation of headache-attributed burden without recall error The aim of the study was to estimate the national burden attributable to headache disorders in Russia by applying measures of prevalence of HY and its impact on productivity and daily activities in the general population We interviewed a representative population-based sample face-to-face by visiting randomly selected households throughout Russia We randomly selected one adult aged 18–65 years from each We followed a structured questionnaire including diagnostic questions, enquiry into occurrence of HY and various aspects of attributed burden Participation rate was 743% One in seven participants (145%; men 91%: women 193%) reported HY Approximately half of these had one of the subtypes of headache occurring on ≥15 days/month; the remainder had episodic migraine or tension-type headache almost equally Mean duration of headache was 60 ± 44 hours In 883% headache intensity was moderate or severe (mean 21 on a scale 1–3) and in 739% HY impaired daily activity Loss of productivity at work due to headache totalled 26 million person-years/year, or 40% of workforce capacity This estimate exceeded by 70% a previous estimate from the same survey based on recall over the preceding 3 months There was greater impact on other daily activities Recall-error-free estimation shows lost productivity every day due to headache in the Russian population is enormously high Measures to redress these losses – effective structured health-care services supported by educational programmes – should be seen as a public-health priority while almost certainly being cost-saving

Theory of Magnetic Domain Phases in Ferromagnetic Superconductors.

Abstract: Recently discovered superconducting P-doped EuFe_{2}As_{2} compounds reveal the situation when the superconducting critical temperature substantially exceeds the ferromagnetic transition temperature. The main mechanism of the interplay between magnetism and superconductivity occurs to be an electromagnetic one, and a short-period magnetic domain structure was observed just below Curie temperature [V. S. Stolyarov et al., Sci. Adv. 4, eaat1061 (2018)SACDAF2375-254810.1126/sciadv.aat1061]. We elaborate a theory of such a transition and demonstrate how the initial sinusoidal magnetic structure gradually transforms into a solitonlike domain one. Further cooling may trigger a first-order transition from the short-period domain Meissner phase to the self-induced ferromagnetic vortex state, and we calculate the parameters of this transition. The size of the domains in the vortex state is basically the same as in the normal ferromagnet, but with the domain walls which should generate the set of vortices perpendicular to the vortices in the domains.