Institution
Japan Aerospace Exploration Agency
Facility•Tokyo, Japan•
About: Japan Aerospace Exploration Agency is a facility organization based out in Tokyo, Japan. It is known for research contribution in the topics: Galaxy & Telescope. The organization has 4327 authors who have published 12054 publications receiving 208330 citations.
Papers published on a yearly basis
Papers
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TL;DR: This work synthesized and assembled membraneless polyester microdroplets from drying of pools of simple α-hydroxy acid monomers and showed that they can act as plausible prebiotic compartments, showing the droplets’ potential compatibility with and scaffolding ability for nascent biomolecular systems that could have coexisted in complex chemical systems.
Abstract: Compartmentalization was likely essential for primitive chemical systems during the emergence of life, both for preventing leakage of important components, i.e., genetic materials, and for enhancing chemical reactions. Although life as we know it uses lipid bilayer-based compartments, the diversity of prebiotic chemistry may have enabled primitive living systems to start from other types of boundary systems. Here, we demonstrate membraneless compartmentalization based on prebiotically available organic compounds, α-hydroxy acids (αHAs), which are generally coproduced along with α-amino acids in prebiotic settings. Facile polymerization of αHAs provides a model pathway for the assembly of combinatorially diverse primitive compartments on early Earth. We characterized membraneless microdroplets generated from homo- and heteropolyesters synthesized from drying solutions of αHAs endowed with various side chains. These compartments can preferentially and differentially segregate and compartmentalize fluorescent dyes and fluorescently tagged RNA, providing readily available compartments that could have facilitated chemical evolution by protecting, exchanging, and encapsulating primitive components. Protein function within and RNA function in the presence of certain droplets is also preserved, suggesting the potential relevance of such droplets to various origins of life models. As a lipid amphiphile can also assemble around certain droplets, this further shows the droplets’ potential compatibility with and scaffolding ability for nascent biomolecular systems that could have coexisted in complex chemical systems. These model compartments could have been more accessible in a “messy” prebiotic environment, enabling the localization of a variety of protometabolic and replication processes that could be subjected to further chemical evolution before the advent of the Last Universal Common Ancestor.
76 citations
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TL;DR: In this article, a part of the inner jet (1-2 milliarcsec from the core) is resolved in a direction transverse to the flow, and the kinematics of the jet within the first 10 mas.
Abstract: In this first of a series of papers describing polarimetric multifrequency Very Long Baseline Array (VLBA) monitoring of 3C 273 during a simultaneous campaign with the INTEGRAL γ -ray satellite in 2003, we present 5 Stokes I images and source models at 7 mm. We show that a part of the inner jet (1-2 milliarcsec from the core) is resolved in a direction transverse to the flow, and we analyse the kinematics of the jet within the first 10 mas. Based on the VLBA data and simultaneous single-dish flux density monitoring, we determine an accurate value for the Doppler factor of the parsec scale jet, and using this value with observed proper motions, we calculate the Lorentz factors and the viewing angles for the emission components in the jet. Our data indicates a significant velocity gradient across the jet with the components travelling near the southern edge being faster than the components with more northern path. We discuss our observations in the light of jet precession model and growing plasma instabilities.
76 citations
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03 Feb 2016
TL;DR: The proposed approach was validated with a four-wheeled test rover in Mars-analogous terrain, including bedrock, soil, and sand, and successfully estimated terrain types with 82% accuracy with only three labeled images.
Abstract: Identifying terrain type is crucial to safely operating planetary exploration rovers. Vision-based terrain classifiers, which are typically trained by thousands of labeled images using machine learning methods, have proven to be particularly successful. However, since planetary rovers are to boldly go where no one has gone before, training data are usually not available a priori; instead, rovers have to quickly learn from their own experiences in an early phase of surface operation. This research addresses the challenge by combining two key ideas. The first idea is to use both onboard imagery and vibration data, and let rovers learn from physical experiences through self-supervised learning. The underlying fact is that visually similar terrain may be disambiguated by mechanical vibrations. The second idea is to employ the co- and self-training approaches. The idea of co-training is to train two classifiers separately for vision and vibration data, and re-train them iteratively on each other's output. Meanwhile, the self-training approach, applied only to the vision-based classifier, re-trains the classifier on its own output. Both approaches essentially increase the amount of labels, hence enable the terrain classifiers to operate from a sparse training dataset. The proposed approach was validated with a four-wheeled test rover in Mars-analogous terrain, including bedrock, soil, and sand. The co-training setup based on support vector machines with color and wavelet-based features successfully estimated terrain types with 82% accuracy with only three labeled images.
76 citations
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TL;DR: In this paper, a gravitropic mutant of Japanese morning glory (Pharbitis nil or Ipomoea nil), Shidare-asagao (weeping), is defective not only in circumnutation but also in the winding response.
Abstract: Circumnutation and winding in plants are universal growth movements that allow plants to survive despite their sessile nature. However, the detailed molecular mechanisms controlling these phenomena remain unclear. We previously found that a gravitropic mutant of Japanese morning glory (Pharbitis nil or Ipomoea nil), Shidare-asagao (weeping), is defective not only in circumnutation but also in the winding response. This phenotype is similar to that of the Arabidopsis SCARECROW (SCR) mutant. We therefore investigated whether morning glory SCR (PnSCR) is involved in the weeping phenotype. We found that one amino acid was inserted into the highly conserved VHIID motif in weeping-type PnSCR; this mutation caused abnormal endodermal differentiation. We introduced either the mutant or WT PnSCR into Arabidopsis scr mutants for complementation tests. PnSCR of the WT, but not of weeping, rescued the shoot gravitropism and circumnutation of scr. These results show that both the abnormal gravitropism and the circumnutation defect in weeping are attributable to a loss of PnSCR function. Thus, our data show that gravisensing endodermal cells are indispensable for shoot circumnutation and the winding response and that PnSCR is responsible for the abnormal phenotypes of weeping.
76 citations
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06 Jun 2005TL;DR: A new approach, Multi-Objective Design Exploration (MODE), is presented to address Multidisciplinary Design Optimization problems, which reveals the structure of the design space from the trade-off information and visualizes it as a panorama for Decision Maker.
Abstract: A new approach, Multi-Objective Design Exploration (MODE), is presented to address Multidisciplinary Design Optimization problems. MODE reveals the structure of the design space from the trade-off information and visualizes it as a panorama for Decision Maker. The present form of MODE consists of Kriging Model, Adaptive Range Multi Objective Genetic Algorithms, Analysis of Variance and Self-Organizing Map. The main emphasis of this approach is visual data mining. Two data mining examples using high fidelity simulation codes are presented: four-objective aerodynamic optimization for the fly-back booster and Multidisciplinary Design Optimization problem for a regional-jet wing. The first example confirms that two different data mining techniques produce consistent results. The second example illustrates the importance of the present approach because design knowledge can produce a better design even from the brief exploration of the design space.
76 citations
Authors
Showing all 4340 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yasushi Fukazawa | 135 | 882 | 64424 |
Jun Kataoka | 121 | 603 | 54274 |
Tadayuki Takahashi | 112 | 932 | 57501 |
Takaaki Tanaka | 105 | 321 | 41804 |
Yasunobu Uchiyama | 105 | 373 | 39610 |
Satoshi Tanaka | 96 | 739 | 76264 |
Masashi Hazumi | 87 | 708 | 29603 |
K. Izumi | 84 | 229 | 53205 |
Carolus J. Schrijver | 81 | 297 | 29858 |
Satoru Takahashi | 79 | 589 | 28007 |
Chris Done | 79 | 457 | 23210 |
Yasuo Doi | 79 | 370 | 33445 |
Poshak Gandhi | 75 | 481 | 18419 |
Alan M. Title | 74 | 203 | 21923 |
Yoshihiro Ueda | 72 | 576 | 25787 |