Institution
Monroe Carell Jr. Children's Hospital at Vanderbilt
Healthcare•
About: Monroe Carell Jr. Children's Hospital at Vanderbilt is a based out in . It is known for research contribution in the topics: Population & Medicine. The organization has 1046 authors who have published 1262 publications receiving 28063 citations. The organization is also known as: Vanderbilt Children's Hospital.
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TL;DR: Dyslipidemia remained relatively constant over the study period, and adiponectin was not useful as a marker of LD in the perinatally HIV-infected population.
Abstract: Background: HIV-associated lipodystrophy (LD) manifests with fat maldistribution, dyslipidemia, and insulin resistance in some HIV-infected children on antiretroviral therapy. Aim: To assess whether lipid abnormalities in patients with HIV are stable over time. Patients: The perinatally HIV-infected cohort at a medium-sized urban US teaching hospital. Methods: This prospective, observational study consisted of five visits (at entry and 3, 6, 24, and 30 months after entry) during which fasting venous blood samples were drawn for HIV-1 RNA, CD4 lymphocytes, lipid profile, free fatty acids (FFA), glucose, insulin, and adiponectin. IGF-I/IGFBP-3 levels were measured at the first and fifth visits. Results: Of 36 study participants, seven were lipodystrophic, and 30 patients completed all five study visits. LDL-cholesterol, total cholesterol (TC), triglycerides (TG), and FFA levels were significantly higher in patients taking protease inhibitors (PIs). Patients with LD had higher TC and TG levels (both p <0.05), and higher FFA (p = 0.0532). Adiponectin levels did not differ between PI/non-PI and LD/non-LD groups. HDL-cholesterol seemed to decrease, and FFA to increase over time. All IGF-I and all but one IGFBP-3 level were within normal range for age and Tanner stage. Conclusion: Dyslipidemia remained relatively constant over our study period. Adiponectin was not useful as a marker of LD in our population.
20 citations
TL;DR: The incidence of SAE during TPVR in the C3PO-QI registry is high, but mortality is uncommon, and radiation dose is greater than for other congenital interventions and is associated with patient and procedural factors.
20 citations
TL;DR: The design, implementation, and lessons learned from the pilot release of Flu Tool are described as guidance for institutions implementing decision support through a patient portal infrastructure.
20 citations
TL;DR: A case of Rocky Mountain spotted fever encephalitis in a child imaged utilizing diffusion-weighted MRI is presented as well as a brief review of this disease.
Abstract: We present a case of Rocky Mountain spotted fever encephalitis in a child imaged utilizing diffusion-weighted MRI. Although the imaging and clinical manifestations of this entity have been previously described, a review of the literature did not reveal any such cases reported in children utilizing diffusion-weighted imaging. The imaging findings and clinical history are presented as well as a brief review of this disease.
20 citations
20 citations
Authors
Showing all 1056 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Dan M. Roden | 132 | 859 | 67578 |
| Kathryn M. Edwards | 102 | 628 | 39467 |
| Agnes B. Fogo | 98 | 578 | 38840 |
| James E. Crowe | 83 | 430 | 22045 |
| Luc Van Kaer | 79 | 261 | 26242 |
| John A. Phillips | 69 | 270 | 16980 |
| Louis J. Muglia | 68 | 254 | 15777 |
| Douglas B. Johnson | 65 | 331 | 18439 |
| Keith T. Wilson | 63 | 238 | 13002 |
| Michael R. DeBaun | 62 | 369 | 14812 |
| Simon W. Hayward | 61 | 191 | 13131 |
| Wendy L. Stone | 61 | 150 | 17231 |
| Arnold W. Strauss | 60 | 209 | 10792 |
| Dominique Delbeke | 59 | 170 | 14652 |
| Thomas B. Newman | 58 | 239 | 11638 |