Institution
Monroe Carell Jr. Children's Hospital at Vanderbilt
Healthcare•
About: Monroe Carell Jr. Children's Hospital at Vanderbilt is a based out in . It is known for research contribution in the topics: Population & Medicine. The organization has 1046 authors who have published 1262 publications receiving 28063 citations. The organization is also known as: Vanderbilt Children's Hospital.
Papers published on a yearly basis
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TL;DR: It is demonstrated that although B-cells are required for the development of autoimmunity, they are not sufficient to disrupt established tolerance, and non-B-cell antigen-presenting cells may be the critical actors in the establishment of the tolerant state.
Abstract: Although it is well established that B-cells are required for the development of diabetes in the nonobese diabetic (NOD) mouse, the nature of their role remains unknown. Herein, we investigate the hypothesis that B-cells in this autoimmune background actively disrupt the tolerant state of those T-cells with which they interact. We demonstrate that NOD B-cells express elevated levels of crucial molecules involved in antigen presentation (including CD21/35, major histocompatibility complex class II, and CD40), alterations that invite the possibility of inappropriate T-cell activation. However, when chimeric animals are generated in which all B-cells are NOD-derived, a tolerant state is maintained. These data demonstrate that although B-cells are required for the development of autoimmunity, they are not sufficient to disrupt established tolerance. Moreover, non-B-cell antigen-presenting cells may be the critical actors in the establishment of the tolerant state; this function may be absent in NOD mice as they are characterized by deficient professional antigen-presenting cell function.
8 citations
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University of Michigan1, University of Virginia2, University of South Alabama3, Boston Children's Hospital4, University of Oklahoma5, Children's Hospitals and Clinics of Minnesota6, Xavier University of Louisiana7, Riley Hospital for Children8, University of Arizona9, Monroe Carell Jr. Children's Hospital at Vanderbilt10, Roseman University of Health Sciences11, VCU Medical Center12
TL;DR: These recommendations may be used to provide both a conceptual framework and action items for schools of pharmacy, health care systems, and policymakers to work together to increase the quality and quantity of pediatric training, practice, or research initiatives.
Abstract: Children warrant access to care from clinical pharmacists trained in pediatrics. The American College of Clinical Pharmacy Pediatrics Practice and Research Network (ACCP Pediatrics PRN) released an opinion paper in 2005 with recommendations for improving the quality and quantity of pediatric pharmacy education in colleges of pharmacy, residency programs, and fellowships. While progress has been made in increasing the availability of pediatric residencies, there is still much to be done to meet the direct care needs of pediatric patients. The purpose of this Joint Opinion paper is to outline strategies and recommendations for expanding the quality and capacity of pediatric clinical pharmacy practitioners by 1) elevating the minimum expectations for pharmacists entering practice to provide pediatric care; 2) standardizing pediatric pharmacy education; 3) expanding the current number of pediatric clinical pharmacists; and 4) creating an infrastructure for development of pediatric clinical pharmacists and cli...
8 citations
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Stanford University1, Maine Medical Center2, Boston Children's Hospital3, Children's Hospital of Philadelphia4, Oregon Health & Science University5, Monroe Carell Jr. Children's Hospital at Vanderbilt6, American Board of Internal Medicine7, University of Colorado Denver8, University of Virginia9, Boston University10, University of California, San Francisco11
TL;DR: The ABP’s quest for excellence is evident in its rigorous evaluation process and in new initiatives undertaken that not only continually improve the standards of its certification but also advance the science, education, study, and practice of pediatrics.
Abstract: * Abbreviations:
ABP — : American Board of Pediatrics
ABMS — : American Board of Medical Specialties
ACGME — : Accreditation Council for Graduate Medical Education
CBME — : competency-based medical education
EPA — : entrustable professional activity
FOPO — : Federation of Pediatric Organizations
MOC — : Maintenance of Certification
SCTC — : Subspecialty Clinical Training and Certification
The American Board of Pediatrics (ABP) certifies general pediatricians and pediatric subspecialists based on standards of excellence that lead to high-quality health care during infancy, childhood, adolescence, and the transition into adulthood. Thus, central to the ABP’s mission is assurance to the public that a general pediatrician or pediatric subspecialist has successfully completed accredited training and fulfills the continuous evaluation requirements that encompass the 6 core competencies of the Accreditation Council for Graduate Medical Education (ACGME) and the American Board of Medical Specialties (ABMS). The ABP’s quest for excellence is evident in its rigorous evaluation process and in new initiatives undertaken that not only continually improve the standards of its certification but also advance the science, education, study, and practice of pediatrics.
The ABP’s responsibilities and authorities in standard setting and evaluation overlap through interest and influence the responsibilities and authorities assumed by the ACGME through its Pediatric Review Committee in the area of training, as well as those of the American Academy of Pediatrics and the subspecialty societies with respect to advocacy and education. Although the respective organizations have distinct missions and roles, they often work in collaboration and synergy regarding training and advocacy. Nonetheless, standard setting, evaluation, and certification remain the sole purview of the ABP. Because of the centrality of accredited training to certification, a decision by the ABP to offer a subspecialty certificate leads to a petition to the ACGME to accredit training programs. The ABP provides substantial input to the development of initial subspecialty program requirements and periodic revisions through its respective subboards, and the ABP standards for certification heavily influence the content of program requirements.
In the late 1990s, the ACGME and ABMS introduced the concept of competency-based medical education (CBME) with the establishment of 6 domains of competence: patient care, medical knowledge, practice-based …
Address correspondence to David K. Stevenson, MD, Harold K. Faber Professor of Pediatrics, Stanford University School of Medicine, Medical School Office Building, 1265 Welch Rd, X157, Stanford, CA 94305. E-mail: dstevenson{at}stanford.edu
8 citations
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TL;DR: A new methodology to quantitatively assess children's cortical processing of light touch, speech sounds and the multisensory processing of the 2 stimuli, without requiring active subject participation or causing children discomfort is developed.
Abstract: Objective and easy measurement of sensory processing is extremely difficult in nonverbal or vulnerable pediatric patients. We developed a new methodology to quantitatively assess children's cortical processing of light touch, speech sounds and the multisensory processing of the 2 stimuli, without requiring active subject participation or causing children discomfort. To accomplish this we developed a dual channel, time and strength calibrated air puff stimulator that allows both tactile stimulation and sham control. We combined this with the use of event-related potential methodology to allow for high temporal resolution of signals from the primary and secondary somatosensory cortices as well as higher order processing. This methodology also allowed us to measure a multisensory response to auditory-tactile stimulation.
8 citations
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TL;DR: In this article, the authors considered a symptomatic fabella as a diagnosis when common treatments for posterior knee pain have not alleviated the symptoms, and used clinical documentations of an orthopedist, physiatrist, physical therapist, 2 primary care sports medicine physicians.
Abstract: Background. There are multiple causes of posterior knee pain and radicular symptoms. A symptomatic fabella is a rare cause but should be considered in the differential diagnosis. Purpose. Physicians should consider a symptomatic fabella as a diagnosis when common treatments for posterior knee pain have not alleviated the symptoms. Study Design. Case report. Methods. Review of clinical documentations of an orthopedist, physiatrist, physical therapist, 2 primary care sports medicine physicians, and the surgical report of an orthopedist. Results. It took time and resources including several referrals and imaging modalities to make a final diagnosis. Conclusion. Symptomatic fabellae are an uncommon finding but should be considered in the differential diagnosis with an athlete with posterior knee pain. Clinical Relevance. Considerable time and resources were used to ultimately diagnose and treat a NCAA Division 1 athlete. Surgical excision was required of a sesamoid bone that is present in 30% of individuals.
8 citations
Authors
Showing all 1056 results
Name | H-index | Papers | Citations |
---|---|---|---|
Dan M. Roden | 132 | 859 | 67578 |
Kathryn M. Edwards | 102 | 628 | 39467 |
Agnes B. Fogo | 98 | 578 | 38840 |
James E. Crowe | 83 | 430 | 22045 |
Luc Van Kaer | 79 | 261 | 26242 |
John A. Phillips | 69 | 270 | 16980 |
Louis J. Muglia | 68 | 254 | 15777 |
Douglas B. Johnson | 65 | 331 | 18439 |
Keith T. Wilson | 63 | 238 | 13002 |
Michael R. DeBaun | 62 | 369 | 14812 |
Simon W. Hayward | 61 | 191 | 13131 |
Wendy L. Stone | 61 | 150 | 17231 |
Arnold W. Strauss | 60 | 209 | 10792 |
Dominique Delbeke | 59 | 170 | 14652 |
Thomas B. Newman | 58 | 239 | 11638 |