Institution
Northeast Agricultural University
Education•Harbin, China•
About: Northeast Agricultural University is a education organization based out in Harbin, China. It is known for research contribution in the topics: Gene & Population. The organization has 14428 authors who have published 9850 publications receiving 126705 citations. The organization is also known as: Dōngběi Nóngyè Dàxué.
Topics: Gene, Population, Oxidative stress, Chemistry, Apoptosis
Papers published on a yearly basis
Papers
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TL;DR: The excitation-emission matrix spectra have shown that the principal components in excavated MSW comprised humic substances and the MSW was stable by the presence of a peak with wavelength pair of ∼280/420 nm, indicating the stability of MSW.
123 citations
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TL;DR: Findings suggested that L. acidophilus KLDS1.0901 might be used as a new type of antidiabetic drug candidate and reshaped gut microbiota similar to the control group.
Abstract: Diabetes, an endocrine and metabolic disorder, has become the third most non-infectious chronic disease that threatens human health. Type 2 diabetes (T2D) accounts for more than 90% of diabetic patients, mainly caused by environmental factors. Lactic acid bacteria (LAB) exhibit several health benefits to the host including regulating glucose and lipid metabolism and improving oxidative stress and inflammatory response. However, the anti-diabetic mechanism of probiotics has not been elucidated clearly. In this study, the anti-diabetic effects of Lactobacillus acidophilus KLDS1.1003 and KLDS1.0901 on T2D mice were assessed. Oral administration of L. acidophilus KLDS1.1003 and KLDS1.0901 for 6 weeks significantly improved the epithelial barrier function, which in turn lowered inflammation cytokines, including IL-8, TNF-α and IL-1β in liver and colon tissue, and prevented liver and colon tissue injuries to some extent. Additionally, L. acidophilus treatment regulated the expression genes that are related to glucose and lipid metabolism. The two tested strains down-regulated the expression of glycogen synthase kinase 3β (GSK-3β), fatty acid synthase (FAS) and sterol regulatory element-binding transcription factor 1c (SREBP-1c), and up-regulated the expression of protein kinase B (Akt). However, L. acidophilus KLDS1.0901 is better for improving T2D than L. acidophilus KLDS1.1003. Further research showed that L. acidophilus KLDS1.0901 supplementation could reshape gut microbiota, increasing short chain fatty acid-producing bacteria (Blautia, Roseburia and Anaerotruncus) and the level of SCFAs and decreasing the relative abundance of Gram-negative bacteria such as Desulfovibrio, Alistipes and Bacteroides. Notably, L. acidophilus KLDS1.0901 treatment restored the structure of gut microbiota similar to the control group. These findings suggested that L. acidophilus KLDS1.0901 might be used as a new type of antidiabetic drug candidate.
123 citations
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TL;DR: Overall, repeated FT had a detrimental effect on the general functionality of porcine MP, and protein denaturation and aggregation were implicated in the functionality losses.
123 citations
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TL;DR: The present review discusses the novelty in microencapsulation techniques for the safe delivery of green tea polyphenols in food matrices and the encapsulation methods and the coating materials.
123 citations
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TL;DR: The characterization of BC and batch experiment results showed that BC prepared at a higher temperature was more suitable for removing TC, and π-π electron donor-acceptor interactions may have played a dominant role in the adsorption mechanism between the enone structure of TC and aromatic C of BC.
123 citations
Authors
Showing all 14506 results
Name | H-index | Papers | Citations |
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Xin Li | 114 | 2778 | 71389 |
Yongsheng Chen | 107 | 465 | 55962 |
Qian Liu | 90 | 610 | 33341 |
Di Wu | 87 | 965 | 48697 |
Xia Li | 85 | 1121 | 30293 |
Mingyao Liu | 82 | 854 | 31501 |
Jian Jin | 68 | 323 | 17018 |
Tong Wu | 66 | 591 | 19325 |
Xin Liu | 63 | 680 | 22868 |
Yong Qing Fu | 60 | 646 | 15576 |
Yujie Feng | 59 | 414 | 13894 |
Jae H. Kang | 57 | 219 | 11951 |
Qi Zhou | 56 | 299 | 14141 |
Yi-Fan Li | 56 | 214 | 10934 |
Nian X. Sun | 50 | 330 | 9210 |