Qingdao University

About: Qingdao University is a education organization based out in Qingdao, China. It is known for research contribution in the topics: Cancer & Apoptosis. The organization has 35675 authors who have published 27275 publications receiving 374908 citations. The organization is also known as: Qīngdǎo Dàxué.

Optimization, selective and efficient production of CNTs/CoxFe3−xO4 core/shell nanocomposites as outstanding microwave absorbers

Abstract: It is well-known that suitable optimization of electromagnetic parameters is a feature to achieve outstanding electromagnetic wave absorption performances (EMWAPs). Accordingly, an effective way to develop high-performance microwave absorbers is to construct dielectric–magnetic core/shell structure nanocomposites with a controllable microstructure and composition parameters. Herein, we propose a simple route to synthesize core/shell structure nanocomposites consisting of carbon nanotubes (CNTs) as the core and magnetic nanoparticles as the shell via a one-step hydrothermal method. By adjusting the experimental parameters, core/shell structure CNTs/CoxFe3−xO4 nanocomposites with different morphologies, contents of CNTs, Co : Fe molar ratios and types of CNTs were selectively synthesized. Also, the electromagnetic properties and EMWAPs of the obtained samples were highly dependent on their microstructure and composition parameters. Thus, by optimizing these parameters, the designed nanocomposites simultaneously exhibited very small values of minimum reflection loss and broad absorption bandwidth with very thin matching thicknesses. Additionally, the outstanding comprehensive EMWAPs of samples were proven to be attributed to their improved impedance matching, attenuation loss characteristics, dielectric loss abilities and excellent synergetic effect. Generally, considering the simple process, environment-friendly, low cost, controllable production and high stability of the nanocomposites, our findings provide an effective way to optimize electromagnetic properties and design high-performance microwave absorbers.

Li2CO3: A Critical Issue for Developing Solid Garnet Batteries

Abstract: Solid garnet electrolytes are promising solid-state electrolytes because of their favorable ionic conductivity and high stability against Li metal anodes. However, their special surface chemistry greatly affects the practical applications whether in the form of garnet ceramic electrolytes (GCEs) or polymer/garnet electrolytes (PGEs). Even though large-scale production of garnet in an ambient atmosphere is possible, the passivated surface due to air exposure can lead to poor interfacial properties of GCEs with electrodes and low ionic conductivities of PGEs. Understanding the effects of air exposure on garnet structure stability, ion mobility, and interfacial configuration is crucial for better applications of solid garnet electrolytes. In this Perspective, we comprehensively recapitulate the reaction mechanisms and influencing factors of air-induced contaminations. Various surface engineering strategies tailoring garnet particles and/or pellets are reviewed. This Perspective provides insightful guidelines...

Biogenesis, functions and clinical significance of circRNAs in gastric cancer.

Abstract: Gastric cancer (GC) is one of the most common malignant tumours in the world and has high morbidity and mortality. Circular RNAs (circRNAs) are a class of non-coding RNAs with covalently linked circular structures. In recent years, plentiful circRNAs have been discovered that participate in many biological processes, including the initiation and development of tumours. Increasing evidences suggest important biological functions of circRNAs, implying that circRNAs may serve as vital new biomarkers and targets for disease diagnosis and prognosis. Among these, circRNAs are tend to aberrantly expressed and are regarded as potential biomarkers in the carcinogenesis and progression of GC. This review systematically summarised the biogenesis, biological properties and functions of circRNAs, with a focus on their relationship with GC, as well as their probable clinical implications on GC. As our cognition of the relation between circRNAs and GC deepens, more molecular mechanisms of GC progression will be discovered, and new therapeutic strategies will be used for the prevention and treatment of GC.

Understanding SARS-CoV-2 endocytosis for COVID-19 drug repurposing.

Abstract: The quest for the effective treatment against coronavirus disease 2019 pneumonia caused by the severe acute respiratory syndrome (SARS)-coronavirus 2(CoV-2) coronavirus is hampered by the lack of knowledge concerning the basic cell biology of the infection. Given that most viruses use endocytosis to enter the host cell, mechanistic investigation of SARS-CoV-2 infection needs to consider the diversity of endocytic pathways available for SARS-CoV-2 entry in the human lung epithelium. Taking advantage of the well-established methodology of membrane trafficking studies, this research direction allows for the rapid characterisation of the key cell biological mechanism(s) responsible for SARS-CoV-2 infection. Furthermore, 11 clinically approved generic drugs are identified as potential candidates for repurposing as blockers of several potential routes for SARS-CoV-2 endocytosis. More broadly, the paradigm of targeting a fundamental aspect of human cell biology to protect against infection may be advantageous in the context of future pandemic outbreaks.