Saxion University of Applied Sciences

About: Saxion University of Applied Sciences is a education organization based out in Enschede, Netherlands. It is known for research contribution in the topics: Health care & Context (language use). The organization has 390 authors who have published 653 publications receiving 8859 citations. The organization is also known as: Saxion University of Applied Sciences.

A Microfluidic Approach for Biosensing DNA within Forensics

Abstract: Reducing the risk of (cross-)contamination, improving the chain of custody, providing fast analysis times and options of direct analysis at crime scenes: these requirements within forensic DNA analysis can be met upon using microfluidic devices. To become generally applied in forensics, the most important requirements for microfluidic devices are: analysis time, method of DNA detection and biocompatibility of used materials. In this work an overview is provided about biosensing of DNA, by DNA profiling via standard short tandem repeat (STR) analysis or by next generation sequencing. The material of which a forensic microfluidic device is made is crucial: it should for example not inhibit DNA amplification and its thermal conductivity and optical transparency should be suitable for achieving fast analysis. The characteristics of three materials frequently used materials, i.e., glass, silicon and PDMS, are given, in addition to a promising alternative, viz. cyclic olefin copolymer (COC). New experimental findings are presented about the biocompatibility of COC and the use of COC chips for multiple displacement amplification and real-time monitoring of DNA amplification.

SpiroPlay, a Suite of Breathing Games for Spirometry by Kids & Experts

Abstract: We have built and implemented a set of metaphors for breathing games by involving children and experts. These games are made to facilitate prevention of asthma exacerbation via regular monitoring of children with asthma through spirometry at home. To instruct and trigger children to execute the (unsupervised) spirometry correctly, we have created interactive metaphors that respond in real-time to the child's inhalation and exhalation. Eleven metaphors have been developed in detail. Three metaphors have been fully implemented based on current guidelines for spirometry and were tested with 30 asthmatic children. Each includes multi-target incentives, responding to three different target values (inhalation, peak expiration, and complete exhalation). We postulate that the metaphors should use separate goals for these targets, have independent responses, and allow to also go beyond expected values for each of these targets. From the selected metaphors, most children preferred a dragon breathing fire and a soccer player kicking a ball into a goal as a metaphor; least liked were blowing seeds of a dandelion and applying lotion to a dog to grow its hair. Based on this project we discuss the potential and benefits of a suite-of-games approach: multiple games that each can be selected and adapted depending on personal capabilities and interests.

Design of a Model for a Professional Development Programme for a Multidisciplinary Science Subject in the Netherlands.

Abstract: Schools are increasingly integrating multidisciplinary education into their programmes. The Minister of Education, Culture and Science has introduced a new, integrated science subject in secondary education in the Netherlands, called Nature, Life and Technology (NLT). This research note describes the design of a generic model for a professional development programme to prepare teachers with and assist them during the implementation of a multidisciplinary science module. Three sources were used for this design: subject features including school practices, the curriculum design phases, and professional development characteristics, in combination with three factors influencing the quality of the professional development: context, process and content. These sources and factors have been translated into a generic model. Three experts evaluated this generic model: a teacher trainer who was also involved in the development of NLT modules; a biology and NLT teacher who was also involved in a regional NLT information centre; and a chemistry and NLT teacher. Overall, the experts were positive. They judged 12 out of 13 aspects of the model as sufficient or better. They were, however, critical about the issue of whether the model offers sufficient possibilities for participants to familiarise themselves with new subject content knowledge.

The interaction between within-year and between-year effects across ages in elite table tennis in international and national contexts – A further exploration of relative age effects in sports

Abstract: Although relative age effects in sports have been studied worldwide, the underlying mechanisms are still under debate. This study adds to the existing knowledge by providing a further exploration of the within-year and between-year effects and their possible interaction in an individual skill/technique based sport: table tennis. Data of male and female elite players across ages (U15, U18, U21, and senior) were collected from the ranking lists in international (world and Europe) and national contexts (France and the Netherlands). A multi-way frequency analysis per subsample revealed (1) no interaction effects; (2) significant within-year and between-year effects for the U15 players in the international context and male French players; (3) a significant within-year effect in the French U18 category; (4) a significant within-year effect in female European U21; and (5) no within-year effects in the senior category. Table tennis seems to be at risk for within-year and between-year effects specifically within the context of high competitive level for younger players (U15, males, and females), but not for interactions between these effects. Future research should reveal the development of the RAEs over time in a longitudinal study, evaluate influencing constraints, and innovative prevention solutions in a more comprehensive way.

Long-term effectiveness of web-based cognitive behavioral therapy for patients with eating disorders.

Abstract: To evaluate the long-term effectiveness of a web-based therapist-delivered cognitive behavioral therapy (CBT) for patients with eating disorders (ED). We used follow-up data from a randomized controlled trial that evaluated a web-based CBT on ED psychopathology and related health, compared to a waiting list control (WL) condition. As participants of the WL condition started the intervention after their waiting period, follow-up data included participants from both groups. The primary outcome was change from baseline, at 3, 6, and 12-month intervals in ED psychopathology, analyzed using mixed models for repeated measures. Secondary outcomes included body dissatisfaction, BMI, physical health, mental health, self-esteem, quality of life, and social functioning. The population comprised 212 participants in total, in three subgroups: bulimia nervosa (BN; n = 44), binge eating disorder (BED; n = 83), and ED not otherwise specified (EDNOS; n = 85). Treatment effects were sustained during follow-up, with generally large effect sizes for the reduction of ED psychopathology and body dissatisfaction, and small to moderate effect sizes for physical and mental health, self-esteem, social functioning, and quality of life. Most effects were found for all three subgroups, except for long-term improvements in self-esteem and quality of life among participants with BN and EDNOS. This study showed long-term sustainability of treatment effects up to 1-year post-treatment of a web-based therapist-delivered CBT for patients with various ED. Level IV, evidence obtained from multiple time series analysis, with intervention. NTR2415—Dutch Trial Registry ( http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2415 ).