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Showing papers by "Saxion University of Applied Sciences published in 2015"


Journal ArticleDOI
14 Oct 2015-Zdm
TL;DR: A review study of the recent scaffolding literature in mathematics education (2010-2015) based on 21 publications that fulfilled our criteria and 14 articles in this special issue that have scaffolding as a central focus is presented in this article.
Abstract: This article has two purposes: firstly to introduce this special issue on scaffolding and dialogic teaching in mathematics education and secondly to review the recent literature on these topics as well as the articles in this special issue. First we define and characterise scaffolding and dialogic teaching and provide a brief historical overview of the scaffolding metaphor. Then we present a review study of the recent scaffolding literature in mathematics education (2010–2015) based on 21 publications that fulfilled our criteria and 14 articles in this special issue that have scaffolding as a central focus. This is complemented with a brief review of the recent literature on dialogic teaching. We critically discuss some of the issues emerging from these reviews and provide some recommendations. We argue that scaffolding has the potential to be a useful integrative concept within mathematics education, especially when taking advantage of the insights from the dialogic teaching literature.

112 citations


Journal ArticleDOI
TL;DR: Individual monitoring of anthropometrics provides useful information to determine increased risk of injury occurrence in elite-standard youth soccer.
Abstract: The aim of the study was to investigate whether an increased risk of injury occurrence can be determined through frequent anthropometric measurements in elite-standard youth soccer players. Over the course of one season, we followed 101 male elite-standard youth soccer players between 11 and 19 years of age. Height and body mass were monitored at monthly measurement intervals and fat percentage was assessed every 3 months by use of the sum of skinfold method. Growth in height (cm), alternations in body mass index (kg/m(2)), fat percentage and fat-free mass index (kg/m(2)) were calculated. Injuries were recorded in accordance with the recommendations of the FIFA Consensus Model for Injury Registration. Odds ratio scores and 95% confidence intervals were calculated using binary logistic regression analyses. The following anthropometric injury risk factors were identified: ≥ 0.6 centimeter growth per month (p=0.03; OR=1.63; 95% CI: 1.06-2.52), ≥ 0.3 kg/m(2) increase of body mass index value per month (p=0.03; OR=1.61; 95% CI: 1.04-2.49) and low fat percentage; i. e., < 7% for players aged 11-16 and < 5% for players over 16 years (p=0.01; OR=1.81; 95% CI: 1.18-2.76). Individual monitoring of anthropometrics provides useful information to determine increased risk of injury occurrence in elite-standard youth soccer.

68 citations


Journal ArticleDOI
TL;DR: Older adults with an increased thoracic kyphosis are more likely to fall within the next year and clinicians should be aware of the risk of a new fracture.
Abstract: Vertebral fractures, an increased thoracic kyphosis and a flexed posture are associated with falls. However, this was not confirmed in prospective studies. We performed a prospective cohort study to investigate the association between vertebral fractures, increased thoracic kyphosis and/or flexed posture with future fall incidents in older adults within the next year.

68 citations


Journal ArticleDOI
TL;DR: This study examines the effect of regulation feedback in a computer-based formative assessment in the context of searching for information online in 13-year-old students, finding that students consulted significantly more websites for Task 2, compared to Task 1.
Abstract: This study examines the effect of regulation feedback in a computer-based formative assessment in the context of searching for information online. Fifty 13-year-old students completed two randomly selected assessment tasks, receiving automated regulation feedback between them. Student performance was (self-)graded by students and by experts. Expert, as well as student (self)grades showed a significant increase between Task 1 and Task 2. However, further analysis of the expert grades showed significant improvement in performance for girls only. Furthermore, the formative assessment system traced the number of searches and the number of websites consulted per student to complete the two assignments. On average, the results showed that students consulted significantly more websites for Task 2, compared to Task 1. The average number of searches did not differ significantly between Tasks 1 and 2. On the other hand, significant differences were found for those students who, during the evaluation of their performance on Task 1, explicitly stated that they would increase their searches. We examined the effect of regulation feedback in computer-based formative assessment on behaviour and performance.Focus on regulation feedback in Digital Information Skills Measurement tool (DIM).DIM traces student information problem solving behaviour.Applied learning analytics indicates behavioural changes.Performance improvement observed for female respondents only.

52 citations


Journal ArticleDOI
TL;DR: To increase delivery of alcohol screening and brief interventions and decrease patients' alcohol consumption, implementation strategies should include a combination of patient-, professional- and organizational-orientated approaches and involve mid-level health professionals as well as physicians.
Abstract: BACKGROUND AND AIMS: Screening and brief interventions (SBI) delivered in primary health care (PHC) are cost-effective in decreasing alcohol consumption; however, they are underused. This study aims to identify implementation strategies that focus on SBI uptake and measure impact on: (1) heavy drinking and (2) delivery of SBI in PHC. METHODS: Meta-analysis was conducted of controlled trials of SBI implementation strategies in PHC to reduce heavy drinking. Key outcomes included alcohol consumption, screening, brief interventions and costs in PHC. Predictor measures concerned single versus multiple strategies, type of strategy, duration and physician-only input versus that including mid-level professionals. Standardized mean differences (SMD) were calculated to indicate the impact of implementation strategies on key outcomes. Effect sizes were aggregated using meta-regression models. RESULTS: The 29 included studies were of moderate methodological quality. Strategies had no overall impact on patients' reported alcohol consumption [SMD = 0.07; 95% confidence interval (CI) = -0.02 to 0.16], despite improving screening (SMD = 0.53; 95% CI = 0.28-0.78) and brief intervention delivery (SMD = 0.64;95% CI = 0.27-1.02). Multi-faceted strategies, i.e. professional and/or organizational and/or patient-orientated strategies, seemed to have strongest effects on patients' alcohol consumption (P < 0.05, compared with professional-orientated strategies alone). Regarding SBI delivery, combining professional with patient-orientated implementation strategies had the highest impact (P < 0.05). Involving other staff besides physicians was beneficial for screening (P < 0.05). CONCLUSIONS: To increase delivery of alcohol screening and brief interventions and decrease patients' alcohol consumption, implementation strategies should include a combination of patient-, professional- and organizational-orientated approaches and involve mid-level health professionals as well as physicians.

51 citations


Journal ArticleDOI
TL;DR: Interventions directed at the training of these executive functions should be developed and used in higher education in order to improve academic achievement, learning attitude, and motivation.
Abstract: Recent studies in late adolescents (age 17+) show that brain development may proceed till around the 25th year of age. This implies that study performance in higher education could be dependent upon the stage of brain maturation and neuropsychological development. Individual differences in development of neuropsychological skills may thus have a substantial influence on the outcome of the educational process. This hypothesis was evaluated in a large survey of 1760 first-year students at a University of Applied Sciences, of which 1332 are included in the current analyses. This was because of their fit within the age range we pre-set (17-20 years' old at start of studies). Student characteristics and three behavioral ratings of executive functioning (EF) were evaluated with regard to their influence on academic performance. Self-report measures were used: self-reported attention, planning, and self-control and self-monitoring. Results showed that students with better self-reported EF at the start of the first year of their studies obtained more study credits at the end of that year than students with a lower EF self-rating. The correlation between self-control and self-monitoring on the one hand, and study progress on the other, appeared to differ for male and female students and to be influenced by the level of prior education. The results of this large-scale study could have practical relevance. The profound individual differences between students may at least partly be a consequence of their stage of development as an adolescent. Students who show lower levels of attention control, planning, and self-control/self-monitoring can be expected to have a problem in study planning and study progress monitoring and hence study progress. The findings imply that interventions directed at the training of these (executive) functions should be developed and used in higher education in order to improve academic achievement, learning attitude, and motivation.

46 citations


Book ChapterDOI
26 Oct 2015
TL;DR: A set of social behaviors and certain specific features social robots should possess based on user’s experience in a longitudinal home study are provided and whether robots can actually be social is discussed.
Abstract: A common description of a social robot is for it to be capable of communicating in a humanlike manner. However, a description of what communicating in a ‘humanlike manner’ means often remains unspecified. This paper provides a set of social behaviors and certain specific features social robots should possess based on user’s experience in a longitudinal home study, discusses whether robots can actually be social, and presents some recommendations to build better social robots.

45 citations


Journal ArticleDOI
TL;DR: In this paper, a model to understand teacher growth is presented based on teacher learning, which combines a development phase with a class enactment phase, and an existing model, the interconnected model of teacher professional growth, is extended.
Abstract: When curricula change, teachers have to bring their knowledge and beliefs up to date. Two aspects can be distinguished: what do teachers learn and how is it learned. Two groups of teachers were involved during the preparation of a new chemistry curriculum. One group developed student learning material and subsequently enacted this in class. Another group only class-enacted this. Based on teacher learning, a model to understand teacher growth is presented. As the combination of a development phase with a class enactment phase proved instrumental, an existing model, the interconnected model of teacher professional growth, was extended. The consequence is that for teacher learning for a renewal a (re)development phase followed by a class enactment phase is essential

43 citations


Journal ArticleDOI
TL;DR: In this paper, the authors investigated the design and support processes of two teacher design teams assisted by an external facilitator using a case study approach and found that the most conducive support activities and materials were those that could directly be applied in the design process.
Abstract: Supporting Teacher Design Teams (TDTs) during local curriculum development efforts is essential. To be able to provide high-quality support, insights are needed about how TDTs carry out design activities and how support is valued by the members of TDTs and how it affects their design expertise. In this study, the design and support processes of two TDTs assisted by an external facilitator were investigated using a case study approach. The results revealed that support offered to TDTs depended on the contextual boundaries and the focus of the design process. The focus, coherence and form of support affected the opportunities for developing teachers’ design expertise. In both cases, teachers’ curriculum design expertise had grown, whereas their pedagogical content knowledge and subject matter knowledge were hardly developed. Findings show that the most conducive support activities and materials were those that could directly be applied in the design process.

33 citations


Journal ArticleDOI
TL;DR: Advances in three-dimensional neuronal cell culture platform technology contributing to controlled environments for microtissue engineering and analysis of cellular physiological and pathological responses will lead to the development of improved, highly organized in vitro assays to understand, mimic, and treat brain disorders.
Abstract: In this contribution, the authors present our advances in three-dimensional (3D) neuronal cell culture platform technology contributing to controlled environments for microtissue engineering and analysis of cellular physiological and pathological responses. First, a micromachined silicon sieving structure is presented as key parameter for a modified version of a planar tissue culture, allowing seeding of single neurons in pyramidal shaped pores by a hydrodynamic sieve flow. Second, a nanogroove–hydrogel interface is presented as a more biomimetic in vivo representation of neuronal tissues, where 3D culturing is required to reproduce the layered tissue organization, which is observed in the microenvironment of the brain. To further our understanding of uniquely nanopatterned interfaces, the authors evaluated 3D neuronal outgrowth into Matrigel atop of primary cortical cell (CTX) cultured on nanogrooves. The interface facilitates conformation of cell somas and aligned outgrowth in 3D with outgrowth alignment preserved in Matrigel up to 6 μm above the nanogrooved substrate, which has a pattern height of just 108 nm. Finally, with the view to incorporate these guided culture interfaces in our previously designed hybrid Polydimethylsiloxane bioreactor, the authors have also explored 3D cellular culture matrix as a variable in such systems. By analyzing the effect of different gel matrices (Matrigel, PuraMatrix, and collagen-I) on the neuron model cell line SH-SY5Y, the authors bring together the ability to guide neuronal growth in spatially standardized patterns and within a bioreactor potentially coupled to an array of single cells that could facilitate readout of such complex cultures by integration with existing technologies (e.g., microelectrode arrays). Various combinations of these novel techniques can be made and help to design experimental studies to investigate how changes in cell morphology translate to changes in function but also how changes in connectivity relate to changes in electrophysiology. These latest advancements will lead to the development of improved, highly organized in vitro assays to understand, mimic, and treat brain disorders.

32 citations


Journal ArticleDOI
TL;DR: This evaluation demonstrated six test items with acceptable reproducibility, good internal consistency and good prospects for validity in the motor skills assessment, which seems to be a reproducible, objective part of a talent development programme.
Abstract: A motor skills assessment could be helpful in talent development by estimating essential perceptuo-motor skills of young players, which are considered requisite to develop excellent technical and tactical qualities. The Netherlands Table Tennis Association uses a motor skills assessment in their talent development programme consisting of eight items measuring perceptuo-motor skills specific to table tennis under varying conditions. This study aimed to investigate this assessment regarding its reproducibility, internal consistency, underlying dimensions and concurrent validity in 113 young table tennis players (6–10 years). Intraclass correlation coefficients of six test items met the criteria of 0.7 with coefficients of variation between 3% and 8%. Cronbach’s alpha valued 0.853 for internal consistency. The principal components analysis distinguished two conceptually meaningful factors: “ball control” and “gross motor function.” Concurrent validity analyses demonstrated moderate associations betwe...

Proceedings ArticleDOI
10 Jun 2015
TL;DR: In this article, a comparative case study between non-interactive and interactive public displays in the urban environment is presented, where the authors evaluate the effect of non-and interactive displays on attracting attention, engaging people, improving social dynamics within and among groups of viewers, and catering for the suitable time of day.
Abstract: This paper describes a comparative case study that aims to uncover the quantifiable differences between non-interactive and interactive public displays in the urban environment. The study involved a large temporary interactive public display on a central city square showing a selection of custom-made content. We have evaluated the effect on passers-by and spectators in two conditions: 1) non-interactive (2102 passers-by, 228 viewers), by showing a content loop, and 2) interactive (1676 passers-by, 257 viewers), by adding physical pushbuttons for content selection and gaming. We discuss the influence of non-interactive and interactive public displays on: 1) attracting attention, 2) engaging people, 3) improving social dynamics within and among groups of viewers, and 4) catering for the suitable time of day. Based on our observations, we provide quantitative support for the hypothesis that interactive displays are more successful than non-interactive displays to engage viewers, and to make city centers more lively and attractive.

Journal ArticleDOI
TL;DR: Physical therapists' kinesiophobic beliefs negatively influence lifting capacity of healthy adults, and during everyday clinical practice, physical therapists should be aware of the influence of their kinesuophobic beliefs on patients' functional ability.
Abstract: Background Physical therapists' recommendations to patients to avoid daily physical activity can be influenced by the therapists' kinesiophobic beliefs. Little is known about the amount of influence of a physical therapist's kinesiophobic beliefs on a patient's actual lifting capacity during a lifting test. Objective The objective of this study was to determine the influence of physical therapists' kinesiophobic beliefs on lifting capacity in healthy people. Design A blinded, cluster-randomized cross-sectional study was performed. Methods The participants (n=256; 105 male, 151 female) were physical therapist students who performed a lifting capacity test. Examiners (n=24) were selected from second-year physical therapist students. Participants in group A (n=124) were tested in the presence of an examiner with high scores on the Tampa Scale of Kinesiophobia for health care providers (TSK-HC), and those in group B (n=132) were tested in the presence of an examiner with low scores on the TSK-HC. Mixed-model analyses were performed on lifting capacity to test for possible (interacting) effects. Results Mean lifting capacity was 32.1 kg (SD=13.6) in group A and 39.6 kg (SD=16.4) in group B. Mixed-model analyses revealed that after controlling for sex, body weight, self-efficacy, and the interaction between the examiners' and participants' kinesiophobic beliefs, the influence of examiners' kinesiophobic beliefs significantly reduced lifting capacity by 14.4 kg in participants with kinesiophobic beliefs and 8.0 kg in those without kinesiophobic beliefs. Limitations Generalizability to physical therapists and patients with pain should be studied. Conclusions Physical therapists' kinesiophobic beliefs negatively influence lifting capacity of healthy adults. During everyday clinical practice, physical therapists should be aware of the influence of their kinesiophobic beliefs on patients' functional ability.

Journal ArticleDOI
01 Sep 2015-Dementia
TL;DR: The use of technology to structure and support the daily activities of the residents in a small-scale group accommodation (SSGA) for dementia is a new innovation in the Netherlands as mentioned in this paper.
Abstract: BackgroundUse of technology to structure and support the daily activities of the residents in a small-scale group accommodation (SSGA) for dementia is a new innovation in the Netherlands. This pape...

Proceedings ArticleDOI
31 Aug 2015
TL;DR: The results show that, although most people prefer a humanoid robot for domestic purposes, the role for which a social robot is build affects the choice for a robotic appearance made by potential future users.
Abstract: Robotics researchers foresee that robots will become ubiquitous in our natural environments, such as our homes. For a successful diffusion of social robots, it is important to study the user acceptance of such robots. In an online survey, we have investigated the acceptance of three different possible roles for domestic social robots and the preferred appearance. The results show that, although most people prefer a humanoid robot for domestic purposes, the role for which a social robot is build affects the choice for a robotic appearance made by potential future users. When comparing the acceptance of the three different roles, people evaluate the companion robot more negatively on the different acceptance variables. Implications of these results are discussed.

Journal ArticleDOI
TL;DR: In this article, the authors investigated whether participation in a teacher design team (TDT) is an effective way to increase the science teaching self-efficacy of primary school teachers who vary in their levels of experience and interest in science.
Abstract: The purpose of this study was to establish whether participation in a teacher design team (TDT) is an effective way to increase the science teaching self-efficacy of primary school teachers who vary in their levels of experience and interest in science. A TDT is a group of at least 2 teachers from the same or related subjects working together to (re)design and enact (a part of) their common curriculum (A. Handelzalts, 2009). This study considers the context of a primary school in The Netherlands. Three forms of data were collected to obtain more in-depth data about the value of working in a TDT: the Dutch version of the Science Teaching Efficacy Belief Instrument (P. Fisser, B. Ormel, & C. Velthuis, 2010), an additional TDT questionnaire, and a focus group interview. The results indicate that professional development through a TDT can improve science teaching self-efficacy for teachers with varying levels of experience and interest

Journal ArticleDOI
TL;DR: In this article, the authors explored factors that contribute to gender-based difference in engineering education, using an interactionalist framework, and found that female students outperform male students.
Abstract: Background In Dutch engineering education, female students outperform male students. Using an interactionalist framework, this study explores factors that contribute to this gender-based difference. Purpose This study aims to answer two questions: Do female and male students differ in background characteristics, engagement factors, and academic success? Are differences in the relationships among background characteristics, engagement factors, and academic success gender-specific? Design/method Data on male and female engineering undergraduate students from five Dutch universities were subjected to linear structural modeling to compare potential gender differences in the relationships among the focal variables. Two structural models were considered. Results Female students spent more time on independent study, reported more social integration, completed more credits, and were more likely to stay in engineering than were male students. Academic integration and intention to persist were important for completion of credits for both genders. Social integration was only important for men’s academic success. Females seemed to benefit less from good preparation through active learning during secondary education, and the effect of a high grade point average on math was negative for females but positive for males. Conclusions Interactionalist concepts can explain academic success, but the relationships among concepts vary by gender. Males’ intentions to persist in engineering are an outcome of engagement processes during the first year, whereas females’ intentions to persist in engineering are manifest at the start of the first year.

Journal ArticleDOI
TL;DR: In this article, the authors focus on the energy governance question whether some forms of collaboration actually are about public governance, as they effectively lean on government involvement, and they conclude that governmental influence can take a "disguised" form by quasi-private organizations, with major normative consequences for the mode of sustainable energy governance.
Abstract: An important avenue toward a proper ‘energy transition’ through regional and local projects is for government to collaborate with private sector organizations. In the energy sector, these latter organizations are often already involved in private-private partnerships for collaboration toward energy transition. This article focuses on the energy governance question whether in fact some of these forms of collaboration actually are about public governance, as they effectively lean on government involvement. This seems to be the case in the construction of biogas infrastructures for the production and distribution of green gas. This contribution discusses, on the basis of the case ‘Biogas grid Noordoost Fryslân’, if such collaboration should in fact be labeled as public-private partnership (PPP). In the energy governance discourse, this issue is important because in the organization of PPP, the public interest of energy transition comes with specific normative safeguards, originating in public law. This article provides a legal normative assessment on the basis of a specific case, the Biogas grid Noordoost Fryslân. The relevant empirical data on this case is gathered by a document study, including research reports, policy plans, project documents, and by interviews. Experts from the Dutch energy sector were face-to-face interviewed by a semi-structured questionnaire. The analysis uses the concept of PPP in relation to public authority. On the basis of a confrontation between the results from literature and from the results of empirical case study of a biogas grid in the Dutch region Noordoost Fryslân, we conclude that governmental influence can take a ‘disguised’ form by ‘quasi’ private organizations, with major normative consequences for the mode of sustainable energy governance. Administrative law in particular poses (binding) criteria for safeguarding public interests, such as on transparency, relevant also to the mode of governance applied in the promotion of renewable energy. Public standards for governance of renewable energy projects have to be sufficiently safeguarded, as regards their form and content of steering, while at the same time retaining the advantages, which ensue from private party involvement within PPP.

Book ChapterDOI
01 Jan 2015
TL;DR: In this article, a discussion of the problems with denim waste and options for its high added value recycling is discussed, as well as the importance of design for recycling in denim, the options for upcycling denim waste, and the possibilities for denim production from other waste materials are discussed.
Abstract: This chapter begins with a discussion of the problems with denim waste and options for its high added value recycling. It then focuses on recovery techniques for both industrial and post consumer denim waste. It further elaborates on recycling techniques for denim waste in the development of high value end products. The importance of design for recycling (D4R) in denim, the options for upcycling denim waste and the possibilities for denim production from other waste materials are also discussed. Finally, environmental aspects and future trends in denim recycling are discussed.

29 Jun 2015
TL;DR: A semantic map of words related with creativity based on association studies performed by human subjects and augmented with words derived from the literature to empirically derive terms which can be used to rate processes or products of computational creativity.
Abstract: We present a semantic map of words related with creativity. The aim is to empirically derive terms which can be used to rate processes or products of computational creativity. The words in the map are based on association studies performed by human subjects and augmented with words derived from the literature (based on human raters). The words are used in a card sorting study to investigate the way they are categorized by human subjects. The results are arranged in a heat map of word relations based on a hierarchical cluster analysis. The cluster analysis and a principal component analysis provide a set of five to six clusters of items related to each other, and as clusters related to creativity. These clusters could form a basis for scales used to rate aspects of computational creativity.

Journal ArticleDOI
TL;DR: Evidence for the effectiveness of a variety of workplace interventions in the meat processing industry is presented, with limited evidence for effectiveness of ergonomic interventions, moderate evidence of a skin protection intervention, and strong evidence for Q fever vaccination.
Abstract: To investigate the effectiveness of occupational health interventions in the meat processing industry on work and health-related outcomes. A systematic literature review was performed. PubMed, Embase, and The Cochrane Library were searched. Studies were included when they reported on an intervention among employees in the meat processing industry and with outcomes related to work or health. Studies were assessed on risk of bias, and data were synthesized by type of intervention. A total of 13 articles reporting on two randomized controlled trials and nine non-randomized intervention studies were retrieved. Studies were categorized into three topics: ergonomics programs, skin protection, and Q fever vaccination. All studies had high risk of bias. Based on four studies, there was limited evidence for workplace health and safety programs showing reductions in musculoskeletal injury severity, reduction of lost work days, and reduction of costs and claims for several musculoskeletal disorders. There was limited evidence for added rest breaks resulting in improved productivity at the end of a workday and in reductions of perceived discomfort in various body regions at the end of the workday. One study on skin protection showed reductions of eczema prevalence, although evidence was moderate. Based on four studies, there was high-quality evidence for strong effectiveness of Q fever vaccination. This review presents evidence for the effectiveness of a variety of workplace interventions. There was limited evidence for effectiveness of ergonomic interventions, moderate evidence of a skin protection intervention, and strong evidence for Q fever vaccination.

Journal ArticleDOI
26 Mar 2015-Sensors
TL;DR: This work surveys how sound is used in the literature for global sound classification, age and gender classification, emotion recognition, person verification and identification and indoor and outdoor environmental sound classification to conclude that for indoor context awareness, the low-cost algorithms for feature extraction perform equally well as the more computationally-intensive variants.
Abstract: Wireless sensor networks are suitable to gain context awareness for indoor environments. As sound waves form a rich source of context information, equipping the nodes with microphones can be of great benefit. The algorithms to extract features from sound waves are often highly computationally intensive. This can be problematic as wireless nodes are usually restricted in resources. In order to be able to make a proper decision about which features to use, we survey how sound is used in the literature for global sound classification, age and gender classification, emotion recognition, person verification and identification and indoor and outdoor environmental sound classification. The results of the surveyed algorithms are compared with respect to accuracy and computational load. The accuracies are taken from the surveyed papers; the computational loads are determined by benchmarking the algorithms on an actual sensor node. We conclude that for indoor context awareness, the low-cost algorithms for feature extraction perform equally well as the more computationally-intensive variants. As the feature extraction still requires a large amount of processing time, we present four possible strategies to deal with this problem.

Journal ArticleDOI
TL;DR: A model delineating the mechanism and role of Afp14 in the maturation of the Afp particle is proposed, suggesting that the 98 N‐terminal, amino acid residues of afp14 is crucial for the initiation of AfP assembly via baseplate formation.
Abstract: The anti-feeding prophage (Afp), a phage-tail-like particle that causes cessation of feeding in the New Zealand grass grub, Costelytra zealandica, is encoded by 18 open reading frames (afp1-18). C-terminal truncations of afp14 resulted in shortened Afp particles, suggesting that Afp14 is involved in Afp length determination. We constructed an Afp assembly system (afp1-18), wherein Afp14 was truncated after the N-terminal 88 residues. This construct, when expressed in trans in Escherichia coli expressing a N-terminal 98-amino acid Afp14 construct, yielded fully assembled Afp but no assembled Afp was detected in the case of a N-terminal 96-amino acid Afp14 construct. These results suggested that the 98 N-terminal, amino acid residues of Afp14 is crucial for the initiation of Afp assembly via baseplate formation. Trans-based expression of wild-type afp14 resulted in Afp particles of varying lengths, all of which were shorter than the wild-type Afp particle. On the other hand, similar expression of Afp14 harboring a C-terminal extension (KLLEH(6)) resulted in elongated Afp particles. This information, combined with bioinformatics data, allowed us to propose a model delineating the mechanism and role of Afp14 in the maturation of the Afp particle.

Journal ArticleDOI
TL;DR: Findings from the current study indicate that multifactorial outcomes (age, systolic blood pressure, need for recovery, and overhead work capacity) from a WHS were independently associated with work ability.
Abstract: Background Workers’ health surveillance (WHS) programs commonly measure a large number of indicators addressing health habits and health risks. Recently, work ability and functional capacity have been included as important risk measures in WHS. In order to address work ability appropriately, knowledge of associations with work and health measures is necessary. The objective of this study was to evaluate which of the factors measured in a WHS are independently associated with work ability in a group of meat processing workers. Methods A cross-sectional study was performed in a large meat processing company in The Netherlands. Data were collected during a WHS between February 2012 and March 2014. Personal characteristics, health habits and health-risk indicators, functional capacity, and work-related factors were measured. Work ability was measured with the Work Ability Index and was used as dependent variable. Univariable and multivariable logistic regression analyses were conducted, a receiver operating characteristic curve was constructed and the area under the curve (AUC) was calculated. Results Data sets from 230 employees were used for analyses. The average age was 53 years and the average work ability index score was 39.3. In the final multivariable model age (OR 0.94), systolic blood pressure (OR 1.03), need for recovery (OR 0.56), and overhead work capacity (OR 3.95) contributed significantly. The AUC for this model was 0.81 (95 % CI 0.75–0.86). Conclusion Findings from the current study indicate that multifactorial outcomes (age, systolic blood pressure, need for recovery, and overhead work capacity) from a WHS were independently associated with work ability. These factors can be used to assess employees at risk for low work ability and might provide directions for interventions.

Journal ArticleDOI
TL;DR: Olive oil is discovered in this study as a supportive factor for biofinishes formation, regardless of the wood type, whereas biofinish formation was not detected on wood treated with stand linseed oil.

Journal ArticleDOI
TL;DR: The aim of the e-IMR intervention is to help consumers with severe mental illness to involve others, manage achieving goals, and prevent relapse.
Abstract: Background E-mental health is a promising medium to keep mental health affordable and accessible. For consumers with severe mental illness the evidence of the effectiveness of e-health is limited. A number of difficulties and barriers have to be addressed concerning e-health for consumers with severe mental illness. One possible solution might be to blend e-health with face-to-face delivery of a recovery-oriented treatment, like the Illness Management & Recovery (IMR) programme. This paper describes the development of an e-health application for the IMR programme and the design of an early clustered randomized controlled trial.


Journal ArticleDOI
TL;DR: The results show six P’s that have to be covered to introduce a nation-wide EPR: Purpose, Process and Prerequisites, which show that the main purpose for a patient is the quality of health, that the process of the professional has to be smoothed and that the data quality has to been guaranteed as well as privacy.
Abstract: The objective of this study was to evaluate a decade of Electronic Patient Record development. During the study a second question was added: How to take the next step in the Netherlands? This paper describes the developments but the main results create a framework for the future situation. The USE IT method was used, which is derived from DOI and TAM theory but applies it in a qualitative way. The results show six P’s that have to be covered to introduce a nation-wide EPR. The first three handle the end users of the EPR: Patients, Professionals and the Public. The latter three show the action types of a nation-wide EPR, namely: Purpose, Process and Prerequisites. In conclusion, the combination of these six P’s show that the main purpose for a patient is the quality of health, that the process of the professional has to be smoothed and that the data quality has to be guaranteed as well as privacy

Journal ArticleDOI
TL;DR: Both optimization control methods are equally able to minimize the maximum peak consumption of electric power by the heat pumps, but the time scale MILP method requires much less computational effort.
Abstract: For a new district in the Dutch city Meppel, a hybrid energy concept is developed based on bio-gas co-generation. The generated electricity is used to power domestic heat pumps which supply thermal energy for domestic hot water and space heating demand of households. In this paper, we investigate direct control of the heat pumps by the utility and how the large-scale optimization problem that is created can be reduced significantly. Two different linear programming control methods (global MILP and time scale MILP) are presented. The latter solves large-scale optimization problems in considerably less computational time. For simulation purposes, data of household thermal demand is obtained from prediction models developed for this research. The control methods are compared with a reference control method resembling PI on/off control of each heat pump. The reference control results in a dynamic electricity consumption with many peak loads on the network, which indicates a high level of simultaneous running heat pumps at those times. Both methods of mix integer linear programming (MILP) control of the heat pumps lead to a much improved, almost flat electricity consumption profile. Both optimization control methods are equally able to minimize the maximum peak consumption of electric power by the heat pumps, but the time scale MILP method requires much less computational effort. Future work is dedicated on further development of optimized control of the heat pumps and the central CHP.

Journal ArticleDOI
TL;DR: Interaction offered on a one-to-one basis tailored to individual preferences significantly improved positive interactive behavior of care-dependent residents with dementia during the intervention.
Abstract: Background: The aim was to assess the impact of a one-to-one 30-min individualized interaction per day on the behavior and quality of life of care-dependent residents with dementia. Methods: In a pre-/post-test study, 15 care-dependent residents with dementia (mean age 88.8 years, 86.7% women) were included. Resident behavior was measured using video observation and quality of life using Qualidem. Health care professionals (n = 13) and direct relatives (n = 4) were interviewed about the effect of the intervention. The effect of the intervention was analyzed using the Friedman analysis of variance. Results: The video observation showed that maintaining eye contact, touching, responding to speaking, tracking observable stimuli and asking questions about the activity significantly increased during the intervention. These findings were supported by interviews with nurses who described experiences of making human-to-human contact with the residents. No significant overall changes were found in quality of life. These findings were partially supported by interviews with health care professionals and relatives as some perceived effects beyond the 30-min intervention. Conclusions: Interaction offered on a one-to-one basis tailored to individual preferences significantly improved positive interactive behavior of care-dependent residents with dementia during the intervention. Surveys revealed no significant overall effect of the intervention. The interviews indicated there might be effects beyond the intervention for some residents.