Stanford University

About: Stanford University is a education organization based out in Stanford, California, United States. It is known for research contribution in the topics: Population & Transplantation. The organization has 125751 authors who have published 320347 publications receiving 21892059 citations. The organization is also known as: Leland Stanford Junior University & University of Stanford.

PointNet: Deep Learning on Point Sets for 3D Classification and Segmentation

Abstract: Point cloud is an important type of geometric data structure. Due to its irregular format, most researchers transform such data to regular 3D voxel grids or collections of images. This, however, renders data unnecessarily voluminous and causes issues. In this paper, we design a novel type of neural network that directly consumes point clouds, which well respects the permutation invariance of points in the input. Our network, named PointNet, provides a unified architecture for applications ranging from object classification, part segmentation, to scene semantic parsing. Though simple, PointNet is highly efficient and effective. Empirically, it shows strong performance on par or even better than state of the art. Theoretically, we provide analysis towards understanding of what the network has learnt and why the network is robust with respect to input perturbation and corruption.

De-noising by soft-thresholding

Abstract: Donoho and Johnstone (1994) proposed a method for reconstructing an unknown function f on [0,1] from noisy data d/sub i/=f(t/sub i/)+/spl sigma/z/sub i/, i=0, ..., n-1,t/sub i/=i/n, where the z/sub i/ are independent and identically distributed standard Gaussian random variables. The reconstruction f/spl circ/*/sub n/ is defined in the wavelet domain by translating all the empirical wavelet coefficients of d toward 0 by an amount /spl sigma//spl middot//spl radic/(2log (n)/n). The authors prove two results about this type of estimator. [Smooth]: with high probability f/spl circ/*/sub n/ is at least as smooth as f, in any of a wide variety of smoothness measures. [Adapt]: the estimator comes nearly as close in mean square to f as any measurable estimator can come, uniformly over balls in each of two broad scales of smoothness classes. These two properties are unprecedented in several ways. The present proof of these results develops new facts about abstract statistical inference and its connection with an optimal recovery model. >

Comprehensive molecular portraits of human breast tumours

Abstract: We analysed primary breast cancers by genomic DNA copy number arrays, DNA methylation, exome sequencing, messenger RNA arrays, microRNA sequencing and reverse-phase protein arrays. Our ability to integrate information across platforms provided key insights into previously defined gene expression subtypes and demonstrated the existence of four main breast cancer classes when combining data from five platforms, each of which shows significant molecular heterogeneity. Somatic mutations in only three genes (TP53, PIK3CA and GATA3) occurred at >10% incidence across all breast cancers; however, there were numerous subtype-associated and novel gene mutations including the enrichment of specific mutations in GATA3, PIK3CA and MAP3K1 with the luminal A subtype. We identified two novel protein-expression-defined subgroups, possibly produced by stromal/microenvironmental elements, and integrated analyses identified specific signalling pathways dominant in each molecular subtype including a HER2/phosphorylated HER2/EGFR/phosphorylated EGFR signature within the HER2-enriched expression subtype. Comparison of basal-like breast tumours with high-grade serous ovarian tumours showed many molecular commonalities, indicating a related aetiology and similar therapeutic opportunities. The biological finding of the four main breast cancer subtypes caused by different subsets of genetic and epigenetic abnormalities raises the hypothesis that much of the clinically observable plasticity and heterogeneity occurs within, and not across, these major biological subtypes of breast cancer.

Foundations of Statistical Natural Language Processing

Abstract: Statistical approaches to processing natural language text have become dominant in recent years This foundational text is the first comprehensive introduction to statistical natural language processing (NLP) to appear The book contains all the theory and algorithms needed for building NLP tools It provides broad but rigorous coverage of mathematical and linguistic foundations, as well as detailed discussion of statistical methods, allowing students and researchers to construct their own implementations The book covers collocation finding, word sense disambiguation, probabilistic parsing, information retrieval, and other applications