Taipei Veterans General Hospital

About: Taipei Veterans General Hospital is a healthcare organization based out in Taipei, Taiwan. It is known for research contribution in the topics: Population & Cancer. The organization has 11878 authors who have published 16478 publications receiving 363424 citations. The organization is also known as: Táiběi Róngmín Zǒngyī Yuàn.

A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients.

Abstract: A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients

Association of cognitive impairment, depressive symptoms and sarcopenia among healthy older men in the veterans retirement community in southern Taiwan: A cross-sectional study

Abstract: Aim To evaluate the association of cognitive impairment, depressive mood and sarcopenia among older men living in the veterans retirement community in southern Taiwan Methods This cross-sectional study recruited 353 men aged 65 years and older. In addition to demographic characteristics, all participants were measured for gait speed, handgrip strength and muscle mass by using bioelectrical impedance analysis (BIA). The diagnosis of sarcopenia was made according to the European Working Group on Sarcopenia in Older People criteria. Slow walking speed was defined as ≤0.8 meter/second. Low muscle strength was defined as the handgrip strength less than 22.5 kg which was adjusted according to Taiwanese norms. A height-adjusted muscle mass of 8.87 kg/m2 from a previous Taiwanese study was defined as low muscle mass. Cognitive function was evaluated by the Mini-Mental State Examination (MMSE), and the Geriatric Depression Scale-15 (GDS-15) was used for screening of depressive symptoms. Results Among the 353 participants (mean age 82.7 ± 5.3 years), 30.9% (109/353) were classified as sarcopenic. Multivariate logistic regression showed that sarcopenia was independently associated with cognitive impairment (adjusted OR 3.03, 95% CI 1.63–5.65, P < 0.001) and depressive symptoms (adjusted OR 2.25, 95% CI 1.03–4.89, P = 0.04). Conclusions Sarcopenia was significantly associated with cognitive impairment and depressive symptoms among otherwise healthy older men living in the veterans retirement community. Further outcome study is required to explore the interrelationship of cognition, depressive symptoms and sarcopenia in older adults. Geriatr Gerontol Int 2014; 14 (Suppl. 1): 102–108.

Peripheral nerve lesions: role of high-resolution US.

Abstract: The peripheral nerve is demonstrated as a reticular pattern in a transverse section at high-resolution ultrasonography (US). Its echogenicity is between that of tendon and muscle. High-resolution US applied to lesions of peripheral nerves yields impressive results in that the nerve is highly differentiated from surrounding soft tissue. In cases of trauma, high-resolution US can easily differentiate between a rupture of the nerve bundle and fibroblast infiltration that results in traumatic neuroma. In cases of inflammation or compressive syndrome, high-resolution US can easily demonstrate lesion location and cause. In the evaluation of abnormal masses, high-resolution US cannot clearly differentiate neurofibromas from schwannomas but it can clarify the relationship between tumor and neural trunk and help the clinician plan treatment strategies. The authors discuss the success that can be achieved with the application of high-resolution US in the evaluation of peripheral nerve lesions.