Institution
Taipei Veterans General Hospital
Healthcare•Taipei, Taiwan•
About: Taipei Veterans General Hospital is a healthcare organization based out in Taipei, Taiwan. It is known for research contribution in the topics: Population & Cancer. The organization has 11878 authors who have published 16478 publications receiving 363424 citations. The organization is also known as: Táiběi Róngmín Zǒngyī Yuàn.
Topics: Population, Cancer, Medicine, Hazard ratio, Atrial fibrillation
Papers published on a yearly basis
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TL;DR: In the majority of patients with EKE associated with pyogenic liver abscess, visual outcome is generally poor despite aggressive antibiotic therapy, and physicians should be alert to the development of EKE when patients with diabetes along with K. pneumoniae-induced pyogenic Liver abscess complain of ocular symptoms.
134 citations
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TL;DR: GBE could reduce cytokine-stimulated endothelial adhesiveness by downregulating intracellular reactive oxygen species formation, nuclear factor-&kgr;B and activator protein 1 activation, and adhesion molecule expression in HAECs, supporting the notion that the natural compound Ginkgo biloba may have potential implications in clinical atherosclerosis disease.
Abstract: Objective— This study was conducted to examination whether Ginkgo biloba extract (GBE), a Chinese herb with antioxidant activity, could reduce cytokine-induced monocyte/human aortic endothelial cell (HAEC) interaction, a pivotal early event in atherogenesis. Methods and Results— Pretreatment of HAECs with GBE (50 and 100 μg/mL for 18 hours) significantly suppressed cellular binding between the human monocytic cell line U937 and tumor necrosis factor-α (TNF-α)-stimulated HAECs by using in vitro binding assay (68.7% and 60.1% inhibitions, respectively). Cell enzyme–linked immunosorbent assay and immunoblot analysis showed that GBE (50 μg/mL for 18 hours) significantly attenuated TNF-α–induced cell surface and total protein expression of vascular cellular adhesion molecule-1 and intracellular adhesion molecule-1 (63.5% and 69.2%, respectively; P<0.05). However, pretreatment with probucol (5 μmol/L for 18 hours) reduced the expression of vascular cellular adhesion molecule-1 but not intracellular adhesion mol...
134 citations
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TL;DR: This study shows that the addition of sublingual nitroglycerin to intravenous vasopressin does not alter the efficacy of vasoppressin alone in controlling hemorrhage from esophageal varices, but it does significantly reduce the complications.
134 citations
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TL;DR: In this paper, a retrospective nationwide longitudinal study using the Taiwan National Health Insurance Research Database collected during 1999-2004 was conducted to evaluate annual prevalence and incidence of Type 2 diabetes and examine possible trends among adults in Taiwan.
Abstract: Diabet. Med. 27, 636–643 (2010)
Abstract
Aim To evaluate annual prevalence and incidence of Type 2 diabetes and to examine possible trends among adults in Taiwan.
Methods A retrospective nationwide longitudinal study using the Taiwan National Health Insurance Research Database collected during 1999–2004. Adult patients aged ≥ 20 years old with prevalent and incident Type 2 diabetes were identified using ICD-9-CM diagnostic codes. Age-specific and age-direct-standardized annual incidence and prevalence were calculated to describe their trends in different gender and age group and compared using Poisson regression.
Results During the study years, the age-standardized prevalence of Type 2 diabetes increased from 4.7 to 6.5% for men and from 5.3 to 6.6% for women. The increasing trends in prevalence were significant and higher among people aged < 40 and ≥ 80 years. The age-standardized incidence rates of Type 2 diabetes per 1000 person-years were approximately 7.6 and remain stable for men, but decreasing from 7.7 to 6.9 for women. However, the incidence increased significantly in younger adults aged < 40 years whose relative incidence (RI with 95% confidence interval) was 1.31 (1.20–1.42) for men and 1.04 (1.01–1.08) for women. The incidence trends for people aged ≥ 40 years were decreased for men and women. The differences in incidence trends between age groups and between genders were all statistically significant (all P < 0.001).
Conclusions This study demonstrated a substantial increasing trend in Type 2 diabetes prevalence during 1999–2004 among adults in Taiwan. Despite the incidence decreased in older people, young men aged 20–40 years were most susceptible to higher incidence of Type 2 diabetes.
134 citations
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Sunnybrook Health Sciences Centre1, University of Helsinki2, Harvard University3, University of São Paulo4, University of Copenhagen5, McGill University6, Tel Aviv University7, University of the Mediterranean8, Seoul National University Bundang Hospital9, Duke University10, University of Pittsburgh11, Yale University12, Taipei Veterans General Hospital13, National Institutes of Health14, University of British Columbia15
TL;DR: Understanding the overall risk of suicide deaths and attempts, and the most common methods, are important building blocks to greater awareness and improved interventions for suicide prevention in bipolar disorder.
Abstract: Objectives:Bipolar disorder is associated with elevated risk of suicide attempts and deaths. Key aims of the International Society for Bipolar Disorders Task Force on Suicide included examining the extant literature on epidemiology, neurobiology and pharmacotherapy related to suicide attempts and deaths in bipolar disorder.Methods:Systematic review of studies from 1 January 1980 to 30 May 2014 examining suicide attempts or deaths in bipolar disorder, with a specific focus on the incidence and characterization of suicide attempts and deaths, genetic and non-genetic biological studies and pharmacotherapy studies specific to bipolar disorder. We conducted pooled, weighted analyses of suicide rates.Results:The pooled suicide rate in bipolar disorder is 164 per 100,000 person-years (95% confidence interval = [5, 324]). Sex-specific data on suicide rates identified a 1.7:1 ratio in men compared to women. People with bipolar disorder account for 3.4–14% of all suicide deaths, with self-poisoning and hanging bein...
133 citations
Authors
Showing all 11952 results
Name | H-index | Papers | Citations |
---|---|---|---|
Peng Huang | 95 | 590 | 39098 |
Hui Y. Lan | 86 | 248 | 23383 |
Yau-Huei Wei | 78 | 385 | 22286 |
Chunyu Liu | 76 | 450 | 26738 |
Ching-Yu Cheng | 75 | 541 | 39780 |
Shou-Dong Lee | 75 | 788 | 26066 |
Shih Ann Chen | 73 | 698 | 28441 |
Shuu Jiun Wang | 71 | 502 | 24800 |
Pesus Chou | 65 | 481 | 16907 |
Jong Ling Fuh | 65 | 383 | 19559 |
Shing Jong Lin | 63 | 401 | 13236 |
Charles Y. Chiu | 62 | 236 | 13185 |
Bor-Luen Chiang | 60 | 460 | 13597 |
Tzeng Ji Chen | 60 | 541 | 13644 |
Shih Hwa Chiou | 58 | 262 | 12289 |