Universidade Federal de Rondônia

About: Universidade Federal de Rondônia is a education organization based out in Porto Velho, Brazil. It is known for research contribution in the topics: Population & Snake venom. The organization has 2232 authors who have published 2614 publications receiving 18062 citations.

Pharmacological characterization of cnidarian extracts from the Caribbean Sea: evaluation of anti-snake venom and antitumor properties

Abstract: Cnidarians produce toxins, which are composed of different polypeptides that induce pharmacological effects of biotechnological interest, such as antitumor, antiophidic and anti-clotting activities. This study aimed to evaluate toxicological activities and potential as antitumor and antiophidic agents contained in total extracts from five cnidarians: Millepora alcicornis, Stichodactyla helianthus, Plexaura homomalla, Bartholomea annulata and Condylactis gigantea (total and body wall). The cnidarian extracts were evaluated by electrophoresis and for their phospholipase, proteolytic, hemorrhagic, coagulant, fibrinogenolytic, neuromuscular blocking, muscle-damaging, edema-inducing and cytotoxic activities. All cnidarian extracts showed indirect hemolytic activity, but only S. helianthus induced direct hemolysis and neurotoxic effect. However, the hydrolysis of NBD-PC, a PLA2 substrate, was presented only by the C. gigantea (body wall) and S. helianthus. The extracts from P. homomalla and S. helianthus induced edema, while only C. gigantea and S. helianthus showed intensified myotoxic activity. The proteolytic activity upon casein and fibrinogen was presented mainly by B. annulata extract and all were unable to induce hemorrhage or fibrinogen coagulation. Cnidarian extracts were able to neutralize clotting induced by Bothrops jararacussu snake venom, except M. alcicornis. All cnidarian extracts were able to inhibit hemorrhagic activity induced by Bothrops moojeni venom. Only the C. gigantea (body wall) inhibited thrombin-induced coagulation. All cnidarian extracts showed antitumor effect against Jurkat cells, of which C. gigantea (body wall) and S. helianthus were the most active; however, only C. gigantea (body wall) and M. alcicornis were active against B16F10 cells. The cnidarian extracts analyzed showed relevant in vitro inhibitory potential over the activities induced by Bothrops venoms; these results may contribute to elucidate the possible mechanisms of interaction between cnidarian extracts and snake venoms.

Aterro sanitário como alternativa para a preservação ambiental

Abstract: Os problemas ambientais causados pelos residuos solidos urbanos sao grandes, principalmente quando esses materiais sao lancados na natureza de forma inadequada (Lixoes), implicando a contaminacao do ar, solo e aguas em geral. Para tanto medidas publicas foram criadas para a insercao de locais com menor impacto ambiental, uma delas e a lei 12.305/10, que preve a extincao dos lixoes e a adesao aos aterros sanitarios. Diante disso, o presente artigo buscou descrever por meio de revisao bibliografica os diversos aspectos relacionados aos aterros sanitarios, dando enfoque aos processos construtivos, aos metodos de tratamentos biologicos e ao reuso dos efluentes liquidos do processo. Normal 0 21 false false false PT-BR X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri",sans-serif;}

Antecipação da diagnose foliar em arroz de sequeiro

Abstract: The objective of this work was to evaluate the possibility of anticipation of foliar sampling in upland rice, in order to enable nutritional diagnosis for timely intervention. One hundred and seven leaf samples were collected from genotype trials of Embrapa Rondonia, in the state of Rondonia, Brazil, in three sampling times: anticipated, at 30 and 40 days after sowing (DAS); and standard, at 65 DAS. Composition nutrient diagnosis (CND) norms were obtained for each evaluated time and used for diagnosis on all evaluation times, comparing the results from the potential response to fertilization under two or three nutritional sufficiency classes, and checking the degree of agreement between the diagnostics. The use of two sufficiency classes increases the possibility of anticipating sampling time for foliar diagnosis, which would enable timely nutritional diagnosis to correct or mitigate eventual nutritional deficiencies. The anticipation of foliar diagnosis in upland rice depends on the development of specific nutritional diagnosis norms for each sampling time.

Educação anti-racista: reflexões e contribuições possíveis do ensino de ciências e de alguns pensadores

Abstract: Nos dias atuais, muitos autores vem debatendo a questao do racismo. Entretanto, a questao racial ainda e pouco discutida dentro da comunidade dos pesquisadores de educacao em Ciencias. Por isso, o presente trabalho tem justamente por objetivo introduzir alguns conceitos importantes envolvidos com o racismo, bem como discutir como o racismo se desenvolveu ao longo dos anos. Alem disso, sao apresentadas possiveis contribuicoes do ensino de Ciencias e de alguns pensadores da sociologia e da psicologia da educacao no combate ao racismo presente na sociedade.

Antioxidant Activity and Characterization of the Essential oil from the Roots of Piper Marginatum Jacq.

Abstract: Piper marginatum is traditionally known as "caapeba cheirosa" or "malvarisco", it is a medicinal plant native from Central and South America; its parts are traditionally used in folk medicine to treat stomach problems in general. Due to its importance in folk medicine and because it is a species mainly obtained by extractivism in an indiscrimante manner, this study aimed to extract, identify and quantify its fresh essential oils collected in Porto Velho, the state capital of Rondonia. The extraction of essential oil from the roots of P. marginatum was perfomed by hydrodistillation using a Clevenger graduated apparatus; the oil analysis was performed by gas chromatography with mass spectrometry. Twenty-five compounds were determined in the essential oil, among them, the (E)-anethol, (Z)-anethol, safrol, germacrene D, germacrene B, and bicyclogermacrene, showed higher levels than the other constituents in all collections and the predominant class of essential oils were the monoterpenes, sesquiterpenes and phenylpropanoids.