Institution
Universidade Federal Rural do Rio de Janeiro
Education•Seropédica, Brazil•
About: Universidade Federal Rural do Rio de Janeiro is a education organization based out in Seropédica, Brazil. It is known for research contribution in the topics: Population & Species richness. The organization has 6405 authors who have published 9852 publications receiving 105911 citations.
Papers published on a yearly basis
Papers
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TL;DR: Lophirone B seems to be exposed to the aqueous media as well as accommodated inside the protein cavity, resulting in a moderate affinity for the albumin.
64 citations
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TL;DR: It can be concluded that the combination of thymol and carvacrol (LC50) has a moderate synergetic effect against A. sculptum larvae, whileThymol, combined with carvACrol ( LC50 and 1/2 LC50), has a syner energetic effect against D. nitens larvae.
64 citations
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TL;DR: The aim of this review is to present a literature review on the spilanthol that describes its occurrence, chemistry, extraction and biological activities.
Abstract: Spilanthol (C14H23NO, 221339 g/mol) is a bioactive compound that is found in many different plants that are used as traditional remedies throughout the world It is present in Heliopsis longipes and several species in the genus Acmella, including A oleracea L, also known as paracress and jambu Its leaves and flowers have sensory properties (pungency, tingling, numbing, mouth-watering) that make it a popular spice and ingredient in several Brazilian dishes Spilanthol can exert a variety of biological and pharmacological effects including analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial, antilarvicidal and insecticidal activities So, the aim of this review is to present a literature review on the spilanthol that describes its occurrence, chemistry, extraction and biological activities
64 citations
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TL;DR: Overall, the main dimensions involved in the consumers' perceptions of coalho cheese from different Brazilian regions were identified, thus obtaining comprehensive insights that can be used as a guideline for coalho Cheese producers to develop marketing strategies considering the intra-cultural differences.
64 citations
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TL;DR: In this article, the potential use of the heterocyclic oxadiazole rings in the design and synthesis of new drugs to treat parasitic infections is discussed, and the authors compare all the four isomeric forms of oxadiaide rings as well as discuss the differences and similarities between them.
Abstract: In this review, we present the potential use of the heterocyclic oxadiazole rings in the design and synthesis of new drugs to treat parasitic infections. We intend to compare herein all the four isomeric forms of oxadiazole rings as well as discuss the differences and similarities between them. In addition, we discuss aspects on their reactivity that justify the great importance of both 1,2,4- and 1,3,4-oxadiazoles isomers when compared with their other two isomers. Although some oxadiazole isomers satisfy Huckel's rule, there are differences concerning their aromaticity, which have a great impact on the possible interactions of the oxadiazole ring with biological receptors. The set of works selected from the literature and discussed herein points out the oxadiazole core as an important and versatile scaffold in the development of new chemical entities potentially useful as antiparasitic drugs.
64 citations
Authors
Showing all 6461 results
Name | H-index | Papers | Citations |
---|---|---|---|
Johan Six | 107 | 447 | 49016 |
Sandra Amato | 100 | 1206 | 50094 |
Robert Poulin | 94 | 653 | 34633 |
C. Potterat | 90 | 751 | 37732 |
O.J. Ginther | 87 | 517 | 27914 |
David Murphy | 81 | 549 | 40441 |
Benedetta Mennucci | 75 | 349 | 48307 |
D. Galli | 68 | 541 | 19570 |
Erica Polycarpo | 51 | 286 | 13615 |
J. Peter W. Young | 51 | 117 | 9839 |
Miriam Dupas Hubinger | 47 | 203 | 8227 |
Albert Bursche | 47 | 213 | 9595 |
M. Gandelman | 46 | 128 | 11022 |
Jose Lopes | 42 | 139 | 9214 |
Murilo Rangel | 38 | 80 | 6038 |