Institution
University of Texas at Dallas
Education•Richardson, Texas, United States•
About: University of Texas at Dallas is a education organization based out in Richardson, Texas, United States. It is known for research contribution in the topics: Population & Computer science. The organization has 14986 authors who have published 35589 publications receiving 1293714 citations. The organization is also known as: UT-Dallas & UT Dallas.
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15 Oct 2018TL;DR: In this paper, the authors surveyed the recent research literature and assessed the experimental evaluations carried out by 32 fuzzing papers and found problems in every evaluation they considered and concluded that the general problems in existing experimental evaluations can indeed translate to actual wrong or misleading assessments.
Abstract: Fuzz testing has enjoyed great success at discovering security critical bugs in real software. Recently, researchers have devoted significant effort to devising new fuzzing techniques, strategies, and algorithms. Such new ideas are primarily evaluated experimentally so an important question is: What experimental setup is needed to produce trustworthy results? We surveyed the recent research literature and assessed the experimental evaluations carried out by 32 fuzzing papers. We found problems in every evaluation we considered. We then performed our own extensive experimental evaluation using an existing fuzzer. Our results showed that the general problems we found in existing experimental evaluations can indeed translate to actual wrong or misleading assessments. We conclude with some guidelines that we hope will help improve experimental evaluations of fuzz testing algorithms, making reported results more robust.
316 citations
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TL;DR: The methods employed in the ATLAS experiment to correct for the impact of pile-up on jet energy and jet shapes, and for the presence of spurious additional jets, are described, with a primary focus on the large 20.3 kg-1 data sample.
Abstract: The large rate of multiple simultaneous protonproton interactions, or pile-up, generated by the Large Hadron Collider in Run 1 required the development of many new techniques to mitigate the advers ...
316 citations
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TL;DR: It is demonstrated that levels of hMCIP1 producing no apparent deleterious effects in cells of the normal heart are sufficient to inhibit several forms of cardiac hypertrophy, and suggest an important role for calcineurin signaling in diverse forms of cardiomyopathy.
Abstract: Signaling events controlled by calcineurin promote cardiac hypertrophy, but the degree to which such pathways are required to transduce the effects of various hypertrophic stimuli remains uncertain. In particular, the administration of immunosuppressive drugs that inhibit calcineurin has inconsistent effects in blocking cardiac hypertrophy in various animal models. As an alternative approach to inhibiting calcineurin in the hearts of intact animals, transgenic mice were engineered to overexpress a human cDNA encoding the calcineurin-binding protein, myocyte-enriched calcineurin-interacting protein-1 (hMCIP1) under control of the cardiac-specific, α-myosin heavy chain promoter (α-MHC). In unstressed mice, forced expression of hMCIP1 resulted in a 5–10% decline in cardiac mass relative to wild-type littermates, but otherwise produced no apparent structural or functional abnormalities. However, cardiac-specific expression of hMCIP1 inhibited cardiac hypertrophy, reinduction of fetal gene expression, and progression to dilated cardiomyopathy that otherwise result from expression of a constitutively active form of calcineurin. Expression of the hMCIP1 transgene also inhibited hypertrophic responses to β-adrenergic receptor stimulation or exercise training. These results demonstrate that levels of hMCIP1 producing no apparent deleterious effects in cells of the normal heart are sufficient to inhibit several forms of cardiac hypertrophy, and suggest an important role for calcineurin signaling in diverse forms of cardiac hypertrophy. The future development of measures to increase expression or activity of MCIP proteins selectively within the heart may have clinical value for prevention of heart failure.
316 citations
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TL;DR: In this article, the determinants of foreign direct investment of service multinationals based in the "triad" regions: Japan, Western Europe and North America are empirically investigated and hypotheses that are developed based on findings of manufacturing FDI and studies of single service industries are tested.
Abstract: In this study we empirically investigate the determinants of foreign direct investment of service multinationals based in the “triad” regions: Japan, Western Europe and North America. Foreign investment decisions of 168 of the largest service firms in nine service industries over the period 1976–1986 are analyzed and hypotheses that are developed based on findings of manufacturing FDI and studies of single service industries are tested using a logistic regression model. The applicability of the MNE-FDI theories to service MNEs is tested empirically over a broad range of MNE home countries and service industries. Differences in the international behavior of service MNEs based in different countries are uncovered and analyzed.
316 citations
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TL;DR: This work explicitly investigates the marketing-manufacturing trade-off and derive analytical implications for three possible design configurations: unique, premium-common, and basic-common to develop an index that can rank order components in terms of their attractiveness for commonality.
Abstract: Product design decisions substantially affect the cost and revenue drivers. A design configuration with commonality can lower manufacturing cost. However, such a design may hinder the ability to extract price premiums through product differentiation. We explicitly investigate the marketing-manufacturing trade-off and derive analytical implications for three possible design configurations: unique, premium-common, and basic-common. Our model considers two distinct segments of consumers. Some of the implications of our analysis are not readily apparent. For example, when the high-quality component is made common, the average quality of the products offered to the two segments increases. One may infer that with higher average quality, higher prices or higher total revenues might ensue. However, this may not be the case, as detailed in the paper. Finally, our analysis provides a useful framework to develop an index that can rank order components in terms of their attractiveness for commonality.
315 citations
Authors
Showing all 15148 results
Name | H-index | Papers | Citations |
---|---|---|---|
Eugene Braunwald | 230 | 1711 | 264576 |
Younan Xia | 216 | 943 | 175757 |
Eric N. Olson | 206 | 814 | 144586 |
Thomas C. Südhof | 191 | 653 | 118007 |
Scott M. Grundy | 187 | 841 | 231821 |
Jing Wang | 184 | 4046 | 202769 |
Eric Boerwinkle | 183 | 1321 | 170971 |
Eric J. Nestler | 178 | 748 | 116947 |
John D. Minna | 169 | 951 | 106363 |
Elliott M. Antman | 161 | 716 | 179462 |
Adi F. Gazdar | 157 | 776 | 104116 |
Bruce D. Walker | 155 | 779 | 86020 |
R. Kowalewski | 143 | 1815 | 135517 |
Joseph Izen | 137 | 1433 | 98900 |
James A. Richardson | 136 | 363 | 75778 |