Institution
University of Texas at Dallas
Education•Richardson, Texas, United States•
About: University of Texas at Dallas is a education organization based out in Richardson, Texas, United States. It is known for research contribution in the topics: Population & Computer science. The organization has 14986 authors who have published 35589 publications receiving 1293714 citations. The organization is also known as: UT-Dallas & UT Dallas.
Papers published on a yearly basis
Papers
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TL;DR: A review of the genetic types and geochemical processes that have formed ‘metalliferous’ coals around the world is presented in this article, with an emphasis on elements in coal that are currently being extracted from coal as raw material (Ge and U) or have, in our opinion, the best chance for such use (REE, Ag, Au, and PGE).
333 citations
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TL;DR: Keyhole umbilical nephrectomy utilizing articulating laparoscopic instrumentation to facilitate triangulation is feasible and safe and successful completion is demonstrated both in a porcine model and in the 3 human patients.
332 citations
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TL;DR: Creation of Hand1/2 double mutant mice revealed gene dose-sensitive functions of Hand transcription factors in the control of cardiac morphogenesis and ventricular gene expression and demonstrate that Hand factors play pivotal and partially redundant roles in cardiac Morphogenesis, cardiomyocyte differentiation and cardiac-specific transcription.
Abstract: The basic helix-loop-helix transcription factors Hand1 and Hand2 display
dynamic and spatially restricted expression patterns in the developing heart.
Mice that lack Hand2 die at embryonic day 10.5 from right ventricular
hypoplasia and vascular defects, whereas mice that lack Hand1 die at embryonic
day 8.5 from placental and extra-embryonic abnormalities that preclude
analysis of its potential role in later stages of heart development. To
determine the cardiac functions of Hand1, we generated mice harboring a
conditional Hand1-null allele and excised the gene by
cardiac-specific expression of Cre recombinase. Embryos homozygous for the
cardiac Hand1 gene deletion displayed defects in the left ventricle
and endocardial cushions, and exhibited dysregulated ventricular gene
expression. However, these embryos survived until the perinatal period when
they died from a spectrum of cardiac abnormalities. Creation of
Hand1/2 double mutant mice revealed gene dose-sensitive functions of
Hand transcription factors in the control of cardiac morphogenesis and
ventricular gene expression. These findings demonstrate that Hand factors play
pivotal and partially redundant roles in cardiac morphogenesis, cardiomyocyte
differentiation and cardiac-specific transcription.
332 citations
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TL;DR: In this paper, the authors used an analysis of variations in category performance across retailers to infer the key drivers of effective category management and how those drivers depend on the role the category plays in the overall retail portfolio, and found that the best performing retailers: (a) offer broader assortments, (b) have strong private label programs, charge significantly lower everyday prices, and (c) use feature advertising to drive store traffic and display to increase in-store purchases.
332 citations
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Eppley Institute for Research in Cancer and Allied Diseases1, University of Nebraska Medical Center2, University of Nebraska–Lincoln3, University of Texas MD Anderson Cancer Center4, Cornell University5, University of Málaga6, Harvard University7, University of Texas at Dallas8, University of Colorado Denver9, Stony Brook University10, University of Michigan11
TL;DR: A widely prevalent mechanism of resistance to gemcitabine in pancreatic cancer is established, whereby increased glycolytic flux leads to glucose addiction in cancer cells and a corresponding increase in pyrimidine biosynthesis to enhance the intrinsic levels of deoxycytidine triphosphate (dCTP).
331 citations
Authors
Showing all 15148 results
Name | H-index | Papers | Citations |
---|---|---|---|
Eugene Braunwald | 230 | 1711 | 264576 |
Younan Xia | 216 | 943 | 175757 |
Eric N. Olson | 206 | 814 | 144586 |
Thomas C. Südhof | 191 | 653 | 118007 |
Scott M. Grundy | 187 | 841 | 231821 |
Jing Wang | 184 | 4046 | 202769 |
Eric Boerwinkle | 183 | 1321 | 170971 |
Eric J. Nestler | 178 | 748 | 116947 |
John D. Minna | 169 | 951 | 106363 |
Elliott M. Antman | 161 | 716 | 179462 |
Adi F. Gazdar | 157 | 776 | 104116 |
Bruce D. Walker | 155 | 779 | 86020 |
R. Kowalewski | 143 | 1815 | 135517 |
Joseph Izen | 137 | 1433 | 98900 |
James A. Richardson | 136 | 363 | 75778 |