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Institution

University of the Algarve

EducationFaro, Portugal
About: University of the Algarve is a education organization based out in Faro, Portugal. It is known for research contribution in the topics: Population & Tourism. The organization has 3649 authors who have published 10303 publications receiving 233536 citations.


Papers
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Journal ArticleDOI
TL;DR: The use of PD-L1 expression as a biomarker increases cost-effectiveness of immunotherapy but also diminishes the number of potential life-years saved.

64 citations

Journal ArticleDOI
TL;DR: It is demonstrated that sperm production in this species is very low and variable according to the type of males, and a previous selection of males according to their fluency, sperm production and provenience should be taken into account in the establishment of a S. senegalensis broodstock.

64 citations

Journal ArticleDOI
TL;DR: In this paper, the authors compared univariate and multivariate techniques based on species compositions by number and weight, and the commercial/total catch ratio in terms of weight and number.

64 citations

Journal ArticleDOI
TL;DR: It is demonstrated that the blackberry anthocyanin-rich extract (BE) can modulate gut microbiota composition and counteract some of the features of HF-diet induced dysbiosis, suggesting that dietary manipulation of the gut microbiota with Anthocyanins can attenuate the neurologic complications of obesity, thus expanding the classification of psychobiotics to anthocianins.
Abstract: High-fat (HF) diets are thought to disrupt the profile of the gut microbiota in a manner that may contribute to the neuroinflammation and neurobehavioral changes observed in obesity. Accordingly, we hypothesize that by preventing HF-diet induced dysbiosis it is possible to prevent neuroinflammation and the consequent neurological disorders. Anthocyanins are flavonoids found in berries that exhibit anti-neuroinflammatory properties in the context of obesity. Here, we demonstrate that the blackberry anthocyanin-rich extract (BE) can modulate gut microbiota composition and counteract some of the features of HF-diet induced dysbiosis. In addition, we show that the modifications in gut microbial environment are partially linked with the anti-neuroinflammatory properties of BE. Through fecal metabolome analysis, we unravel the mechanism by which BE participates in the bilateral communication between the gut and the brain. BE alters host tryptophan metabolism, increasing the production of the neuroprotective metabolite kynurenic acid. These findings strongly suggest that dietary manipulation of the gut microbiota with anthocyanins can attenuate the neurologic complications of obesity, thus expanding the classification of psychobiotics to anthocyanins.

64 citations

Journal ArticleDOI
TL;DR: This review of recent developments in the understanding of brown algal evolution based on modern advances in phylogenetics and functional genomics discusses promising avenues for future research opened by genomic datasets, directions that are expected to reveal critical insights into brownAlgae evolution in past, present, and future oceans.
Abstract: The brown algae (Phaeophyceae) are a group of multicellular heterokonts that are ubiquitous in today’s oceans. Large brown algae from multiple orders are the foundation to temperate coastal ecosyst...

64 citations


Authors

Showing all 3723 results

NameH-indexPapersCitations
Shuzhi Sam Ge9788340865
Martin Ingvar7931521363
Fernando Albericio7696526146
Paul Goldberg6838517238
Anders Björkman6428213174
José J. G. Moura6346515490
Karl Magnus Petersson6318514441
Paulo P. Freitas5966713777
Maria João Bebianno5821510445
Ester A. Serrão552929751
Rui Filipe Oliveira5423910225
Deborah M. Power5330010130
Rui Santos523579020
Adelino V.M. Canario522899912
Martyn Pillinger512578556
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202356
2022114
2021745
2020760
2019681
2018645