Showing papers in "American Heart Journal in 1974"

TL;DR: Clinically, it appears useful to categorize antiarrhythmic drugs into four groups in terms of their currently known mechanisms of action, and the effects of verapamil are sufficiently different from those of other known agents to allow the tentative conclusion that its fundamental mode of action represents a fourth (Group IV) class of antiarrHythmic action.

TL;DR: Although slow systemic increase of K + induces asystole in animals, administration to a region of myocardium produces ventricular ectopic beats and fibrillation, the latter effect may be due to re-entry and may be mechanistically similar to the arrhythmias of early ischemia.

TL;DR: This study will examine the secular changes in systolic and diastolic blood pressure according to smoking habits over an interval of five years in a series of healthy white veterans.

TL;DR: Its lack of effects on the HPS make its use relatively safe in patients with infra-His conduction disturbances and its efficacy in controlling the ventricular rate in atrial fibrillation and flutter and the treatment and prophylaxis of re-entrant supraventricular tachycardias is explained.

TL;DR: A dose-related increase in cardiac output and stroke volume was observed with infusion rates up to 5 μg per kilogram per minute in all patients; more rapid infusions resulted in a diminished response in many individuals.

TL;DR: The serum corticoids were markedly elevated on smoking high-nicotine cigarettes and the FFA changes were not related to either the amount of nicotine inhalation or the elevation of serum E.

TL;DR: The data obtained previously in dogs’ and rnan did not include observations concerning coronary blood flow and myocardial metabolism, which seems of critical importance in hypotensive subjects, and the present study was done.

TL;DR: In a 29-year-old woman with systemic lupus erythematosus, death was the result of acute myocardial infarction associated with extensive coronary atherosclerosis.

TL;DR: This study provides a frame of reference for analysis of sequential ventriculograms in patients with coronary artery disease, especially in evaluating changes in the state of the disease or the effects of therapy.

TL;DR: A much higher sensitivity of the myocardium of the pig in comparison to that of the rat or the dog usually used in strees experiments is presumed.

TL;DR: It is found that “ischemic” ECG changes seen during hyperventilation (as well as during exercise) in patients with suspicious histories indicate that very probably no coronary artery disease exists.

TL;DR: In patients aged 49 or less the presence of coronary artery calcification strongly favors the diagnosis of arteriosclerotic heart disease, and calcification of two or three coronary arteries indicated that singlevessel coronary artery disease was unlikely.

TL;DR: Arterial pulse wave velocities, pulse wave contours, and systolic time intervals were recorded in thirty-nine diabetic children and were compared with recordings taken in twenty-seven normal children.

TL;DR: The studies suggest quinidine has antivagal properties which are of clinical significance and may lead to the ventricular tachyarrhythmias implicated in “quinidine syncope” by a re-entrant mechanism.

TL;DR: The hypothesis that the thrombus is a secondary phenomenon related to flow redistribution by collateral vessels in stenosed arteries is supported.

TL;DR: This model indicates that elevated values of fibrinogen and plasma viscosity may play a significant detrimental role following myocardial infarction and it is suggested that modification of plasma Viscosity through a reduction of fibinogen concentration may be a useful clinical technique in cardiology.

TL;DR: Patients on lidocaine infusions for the control of arrhythmias accumulate significant concentrations of lidocane metabolites, and it would seem that MEGX may contribute to the total anti-arrhythmic effect of a lidocain infusion.

TL;DR: The central venous pressure cannot be reliably estimated by inspection of the jugular veins, and large discrepancies were noted in individual cases.

TL;DR: It is suggested that coronary arteriography is a justifiable procedure in a young patient who presents with a clinical picture that is either compatible with or cannot be clearly distinguished from CAD.

TL;DR: Right-sided cardiac pressures were obtained with a Swan-Ganz catheter in 10 patients within the first 24 hours after a myocardial infarction, and phentolamine can greatly improve cardiac function, regardless of the level of the initial blood pressure.

TL;DR: It is proposed that antiarrhythmic drugs could act in this way to abolish the electrical activity of the diseased tissue responsible for arrhythmias without extensive depression of the normal tissue.

TL;DR: In these patients, the result of aortocoronary bypass appears less predictable than in patients with classic angina, and one patient still has documented attacks of variant angina in spite of a patent vein graft.

TL;DR: In patients with low cholesterol levels, an increase of plasma triglycerides was associated with more severe occlusive disease, and the correlation between plasma triglyceride levels and coronary occlusion seemed to be less pronounced than was the case with plasma cholesterol levels.

TL;DR: The mechanism of production of the first and second heart sounds is re-examined on the basis of known physical laws and physiologic experiments of the last decade and a general theory is propounded, which agrees with the observed facts and is in line with previous conclusions of both early and present physiologists.

TL;DR: These cardiovascular changes were uninfluenced by the presence of essential hypertension or ischemic heart disease, but were modified in some instances by drugs which affected the autonomic nervous system.

TL;DR: Of those patients that died due to the PDA, nearly 60 per cent had bronchopulmonary dysplasia as an associated finding and the survival rate in those over 1,000 grams was 80 per cent.