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Showing papers in "Archives of Oral Biology in 1974"


Journal ArticleDOI
TL;DR: With stimulation, the pH, ionic strength and the concentrations of protein, sodium, calcium, chloride and bicarbonate increased in proportion to flow rate, the potassium concentration remained almost constant whilst the magnesium and phosphate concentrations decreased, the former being independent of stimulated flow rate but the latter being inversely related to flow rates.

293 citations


Journal ArticleDOI
TL;DR: A biochemical scheme was developed for the separation of Streptococcus mutans into 5 biotypes, a-e, which correlated with the recognized serotypes a--e, and the biotype identification of the Strep.

242 citations


Journal ArticleDOI
TL;DR: The 14 C-activity in saliva showed a sharp fall during the first few hours, followed by a slow release, with activity still present after 24 hr, and the intra-individual variation, estimated by five mouth rinses at 1-week intervals, averaged ±4 per cent.

198 citations


Journal ArticleDOI
TL;DR: It is concluded that the caries-preventive effect of the ingested F was related both to elevated F levels in the surface enamel and to less retentive pits and fissures.

171 citations


Journal ArticleDOI
TL;DR: A new method for maintaining anaerobiosis during collection of a sample from root canals, as well as during transportation and identification was developed, and nearly all of a total of 104 anaerOBes from 377 isolated microorganisms were identified.

158 citations


Journal ArticleDOI
TL;DR: Marked increases in the amylase concentration of saliva occurred in response to sympathetic stimulation in the four subjects studied, accompanied by increases in heart rate and blood pressure and small, variable changes in salivary flow rates.

145 citations


Journal ArticleDOI
TL;DR: The clinical effect of chlorhexidine as a plaque inhibitor seems to be dependent on the retention of the agent in the oral cavity.

145 citations


Journal ArticleDOI
TL;DR: Data are presented which support the view that fibroblasts in the periodontal ligament of the incisor, apart from synthesizing collagen, are also engaged in degrading collagen fibres, necessary to maintain the structural integrity of the ligament in a dynamic situation.

145 citations


Journal ArticleDOI
TL;DR: The oral retention of chlorhexidine-digluconate from rinsing solutions of 0.05, 0.1,0.2 and 0.4 per cent was measured, essentially proportional to the concentration, with a slight deviation towards less retention at the 0.

115 citations


Journal ArticleDOI
TL;DR: There was a sharp drop in the major chromatographical component of enamel protein between stages of cheese-like enamel and chalk-likeEnamel samples at four different stages of development were separated from embryonic bovine teeth by scraping, and demineralized by dialysis against 0.5 M acetic acid.

114 citations


Journal ArticleDOI
TL;DR: Feasibility of analyses for OH and other components in regions as small as 20 μm across has been demonstrated with a view toward analysis of spatial variation of tooth composition, and apatite-like spectra exhibiting both broadening and mode-frequency shifts are shown.

Journal ArticleDOI
TL;DR: There was a significantly higher yield of bacterial mass under conditions of glucose-limitation than under conditionsof nitrogen-limite, and all streptococci formed lactate as the main fermentation product when grown in a medium containing a surplus of glucose with the nitrogen source limiting growth.

Journal ArticleDOI
TL;DR: Haemagglutinating activity was found in 29 out of 59 strains of B. melaninogenicus isolated from human gingival crevices and fimbria-like structures were observed in all strains manifesting haemag GLUTinating activity.

Journal ArticleDOI
TL;DR: Attention is drawn to the diurnal rhythm of enamel formation indicated by prism cross-striations and to the approximately 8-day periodicity of the striae of Retzius, which could be an imperfect synchronization of two or more circadian rhythms, ameloblast activity and general body activity.

Journal ArticleDOI
TL;DR: The orthodontically stimulated rat periodontal ligament (PDL) proved to be a useful experimental model for studying cell proliferation and resulted in a progressive increase in tritiated thymidine ([ 3 H]-T)labelling indices of “PDL fibroblasts”.

Journal ArticleDOI
TL;DR: Microradiography of thin sections of dentine taken from a large sample of human teeth revealed a number of hitherto unknown facts about dentine sclerosis, indicating that the physiological sclerotic process is in some way initiated by the stresses imposed by the oral environment.

Journal ArticleDOI
TL;DR: The complexity of this family of unusual macromolecules is demonstrated and the isolation and characterization of two of its minor members are described.

Journal ArticleDOI
TL;DR: Examination of fibroblasts within the periodontal ligament of functioning lower first molars with the electron microscope revealed the frequent occurrence of membrane-bound intracytoplasmic profiles containing banded collagen, suggesting the cellular basis for connective tissue turnover is the same as for connectives remodelling, namely the fibroblast.

Journal ArticleDOI
TL;DR: The formative stage demonstrated a response to the fluoride in the morphology of the cells and their product, and during maturation, groups of the ameloblasts often were altered with huge intracellular vacuoles, while adjacent enamel appeared to mature normally.

Journal ArticleDOI
TL;DR: Siblings of children with the lesion had a prevalence significantly greater than the total study population, suggesting that factors operating at the family level enhance the occurrence of the hypoplastic lesion in children.

Journal ArticleDOI
TL;DR: Circadian variations have been demonstrated in unstimulated submandibular saliva from 15 subjects for flow-rate, pH and concentrations of sodium, potassium, calcium, chloride, inorganic and total phosphate, protein, nitrogen and carbohydrate.

Journal ArticleDOI
TL;DR: Differences exist between the innervation patterns of primary and permanent teeth, and predictability of unmyelinated innervation quantities from more easily determined myelination quantities is suggested.

Journal ArticleDOI
TL;DR: The demonstration of fibres on the outer surface of these bacteria provides structural evidence for a potential mechanism of adhesion in plaque organisms as both organisms induce experimental periodontal disease in hamsters and gnotobiotic rats.

Journal ArticleDOI
TL;DR: The data show that the turnover of collagen in normal gingiva is inordinately high when compared to the other connective tissues of the same animals, and provide the basis for a new hypothesis which states that the collagen loss observed in inflammatory gingival disease may result from interference with synthesis and turnover ofCollagen.

Journal ArticleDOI
TL;DR: The concept that salivary myoepithelial cells in the cat have a motor parasympathetic innervation is supported, as the extent of the acinar atrophy paralleled the diminution in secretion.

Journal ArticleDOI
TL;DR: Plaque samples from clinically sound bucco-lingual and occlusal and approximal surfaces were examined for the presence of Streptococcus mutans and the percentage of Strep, mutans to total streptococci was also higher in the control group than the caries-free group.

Journal ArticleDOI
TL;DR: The enamel was completed first to the same morphological extent as that of mammalian enamel on which no cementum is laid down, however, the enamel did not become fully mature as assessed by the concentration of calcium measured by elemental X-ray analysis.

Journal ArticleDOI
TL;DR: Chewing of hard food induced, in contrast to that of the soft, more vigorous jaw movements characterized by increased rate and shorter duration of chewing strokes as well as higher frequency and amplitude of spikes in each stroke.

Journal ArticleDOI
TL;DR: Electrical stimulation of the autonomic nerves destined for the submandibular gland of the rat found that in both males and females the granular convoluted tubule cells respond to α-sympathetic stimulation only.

Journal ArticleDOI
TL;DR: Variation of the position of the lower jaw showed that the twitch tension, produced by discrete single stimuli, was greatest when the mouth was opened by about 8 mm from occlusion, which differs from that for voluntary biting power in the human subject.