Showing papers in "Asian Pacific Journal of Tropical Medicine in 2012"
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TL;DR: This review will initially describe current drug regimens and later will provide an overview on few important biochemical and enzymatic machineries that could be utilized as putative drug targets for generation of true antileishmanial drugs.
347 citations
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TL;DR: This review represents an updated scenario on the transmission cycle, epidemiology, clinical features and pathogenicity, diagnosis and treatment, and prevention and control measures of a cestode parasite Echincoccus granulosus causing cystic echinococcosis in humans and animal CE.
147 citations
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TL;DR: Preliminary results suggest promising antimicrobial properties of C. mangga and C. aeruginosa, which may be useful for food preservation, pharmaceutical treatment and natural therapies.
143 citations
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TL;DR: The present meta-analysis reveals that soy isoflavone supplements significantly increase bone mineral density and decrease the bone resorption marker urinary DPD and shows no significant effect on bone formation markers serum bone alkaline phosphatase.
121 citations
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TL;DR: Antioxidant and antimicrobial activity of A. sativum provides scientific basis for its utilization in traditional and folk medicine and demonstrated the insecticidal efficacy of aqueous and methanol extracts against S. litura, a polyphagous insect.
105 citations
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TL;DR: In this article, the authors used time series analysis to study the time variations in the number of leptospirosis cases in relation to the seasonal pattern, and its association with climate factors.
93 citations
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TL;DR: These findings suggest that a generalized inflammatory state may be present in individuals with PTSD.
85 citations
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TL;DR: awareness of these unusual clinical manifestations will help the clinician to arrive at an early diagnosis, resulting in early administration of appropriate antibiotics, and an outline of current knowledge of pathophysiology is outlined.
79 citations
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TL;DR: This study reveals the prevalence and antimicrobial susceptibility pattern of biofilm and non-biofilm producing uropathogenic E. coli strains and indicates that biofilm positive phenotype strains did not correlate well with the tube method for detecting biofilm formation in E. bacteria.
78 citations
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TL;DR: The results of the present study strongly reveal that MENO-F has potent antioxidant activity and hepatoprotective activity against CCl(4)-induced hepatic damage in experimental animals.
65 citations
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TL;DR: It was concluded that the plant of A. cordifolia possesses hepatoprotective as well as antioxidant activities and these activities reside mainly in the ethyl acetate and acetone fractions of methanol leaf extract.
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TL;DR: These results showed first indication of pyrethroid resistance in An.
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TL;DR: In this article, the use of African mistletoe (AM) Viscum album (V. album ) in folkoric medicine to treat diabetes was presented, where the fasting blood glucose (FBG) levels of diabetic rats were monitored for 4 h.
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TL;DR: It is shown that two different doses of tannin supplementation had a favorable effect on plasma glucose and lipid profile concentrations and it also had an influence on attenuating oxidative stress in diabetic tats.
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TL;DR: The results showed that nutmeg oil has higher antioxidant activity than mengkudu oil and bioactive compound(s) will be isolated from the nutmeg essential oil to be developed as antiangiogenic drugs.
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TL;DR: The hydroethanolic extract of young seedless pods of Acacia nilotica has antiulcer activity in pylorus ligation, swimming stress and NSAID induced rat ulcer models, indicating the phenolic component of the extract to be responsible for the activity of the extracts.
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TL;DR: Early warning based on the data in the previous months could assist in improving vector control, community intervention, and personal protection in northeastern Thailand.
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TL;DR: The present study suggests that Hemidesmus indicus has protective activity against arthritis and the activity might be attributed to presence of terpenoid in hydroalcoholic extract, as well as in ethyl acetate fraction.
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TL;DR: A rapid, accurate laboratory confirmative method to simultaneously detect, quantify and differentiate CHIKV and DENV infection by single-step multiplex real-time RT-PCR provides a means for simultaneous early diagnosis of CHikV andDENV in a single- step reaction.
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TL;DR: The fruits of garden egg have anti-inflammatory activity in the models studied and are shown to reduce the fresh egg albumin-induced rat paw oedema and also reduced the granuloma tissue formation in the treated groups when compared to the control.
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TL;DR: The results suggests that AEBM extended protection against various biochemical changes and aortic pathology in hypercholesterolemic rats, and may therefore be useful for therapeutic treatment of clinical conditions associated hyperCholesterolemia.
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TL;DR: This work presents a fatal case of leptospirosis with acute liver failure, respiratory failure and jaundice and encephalopathy in urban India during monsoon.
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TL;DR: The ethanolic leaf extracts of O. sanctum possess lead compounds for the development of antiplasmodial drugs and might be due to the presence of alkaloids, glycosides, flavonoids, phenols, saponins, triterpenoids, proteins, resins, steroids and tannins in the Ethanolic extracts of tested plants.
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TL;DR: The results suggest that mangostins derivatives have the potential to inhibit the growth of cancer cells by inducing apoptosis and also showed the activity as an inhibitor of lipid peroxidation.
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TL;DR: Algeria honey, in-vitro, possess antibacterial activity, and these honey samples were compared with standard antibiotics like ampicillin, penicillin G, amoxicillin, gentamycin, tobramycin, erythromycin and chloramphenicol.
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TL;DR: The diagnosis of toxoplasmosis and rubella is necessary in pregnant women in Burkina Faso because of the low immunization coverage rate of rubella and the high level of exposure to these two infections which can be harmful to the newborn if contracted by women before the third trimester of pregnancy.
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TL;DR: The results indicate that Pterocarpus erinaceus extract produced significant antidiarrheal activity and the action may attribute to inhibition of gastrointestinal movement and fluid secretion.
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TL;DR: The pulp has more BG before the maturation of papaya and it nearly disappeared after papaya matured, while the seed contains BG at every stage, and the hydrolysis product of BG has certain cancer-prevention anti-cancer activities for human.
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TL;DR: Streptomyces sp.
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TL;DR: It is hoped that this study would direct to the establishment of some compounds that could be used to invent new and more potent antimicrobial drugs of natural origin.