Showing papers in "Bone and Mineral in 1988"

TL;DR: Avian, calvarial osteoblast-like cells, from passes 2-5, responded to cyclic strain, by increasing their rates of DNA synthesis and cell division during the first 72 h after initiation of a continuous deformation regimen comprised of 3 cycles per min of 0-24% elongation.

TL;DR: In this paper, a newly developed "spine deformity index" (SDI) was proposed to quantify the extent of vertebral fractures in patients with idiopathic osteoporosis, based on the observation that the heights of all vertebral bodies were related to each other in a predictable and constant manner.

TL;DR: The results suggest that bone mass is influenced by dietary factors other than calcium, and iron, zinc and magnesium intake were positively correlated with forearm BMC in premenopausal women.

TL;DR: The data indicate that osteoporosis is a systemic disease and trabecular bone losses are reflected in the calcaneus as well as in the spine itself, and this use of BMC measurements which has the most promise for the future.

TL;DR: Normative data for the vertebral dimensions should help improve the accuracy of diagnosis of spinal osteoporosis.

TL;DR: A substantial menopause related acceleration of lumbar bone loss in a relatively short time span with its onset in the perimenopausal period is suggested.

TL;DR: It was concluded that pulsatile administration of human PTH(1-34) prevented the development of osteopenia induced by ovariectomy.

TL;DR: Although the results reflect a relative rather than a true sensitivity it appears that PDAH is the better diagnostic measurement for fractures in the earlier stages of spinal osteoporosis.

TL;DR: It is suggested that the difference between child- and adult-cell chambers reflects an age-related decline in the number of marrow osteoprogenitor cells or their potential to undergo terminal osteogenic differentiation.

TL;DR: The data suggest a direct inhibition of osteoblast number and/or function by short-term glucocorticoid administration with unchanged bone resorption leading to a negative bone mineral balance.

TL;DR: Investigation of the long-term in vivo precision of a dual photon spine scanner using three different Gd sources and compared it with that of the single photon scanner found that spinal measurements may require 11.6 times as many participants as the forearm measurements to detect the same changes in bone mass.

TL;DR: It is suggested that Ca intake in early adulthood influences the axial and appendicular bone mass in premenopausal women.

TL;DR: It is found anisotropy of iliac bone to increase as B.Ar decreases, and Tb.Wi is lower in women than in men in the IC site, and a preferential loss of the thinner trabeculae could be seen in this group.

TL;DR: It is speculated that the hyper-alkaline phosphatasia frequently seen in patients with hyperthyroid Graves' disease is partly due to a direct effect of thyroid hormone on osteoblasts or osteoblast-like cells.

TL;DR: The data indicate that there are some small differences in the age-related changes in cortical and trabecular bone, but that the reduction of both types of bone accelerates after the menopause.

TL;DR: A summary of the new system of terminology for bone histomorphometry has been adopted as part of the instructions to authors by all four journals, intended to make the system intelligible to the general readership of the journal.

TL;DR: The calcium-binding properties of purified bovine SP-I are examined and it is found that it binds 14 or more Ca2+ at low affinity, consonant with earlier speculation thatSP-I serves as a 'condensing' agent within secretory granules.

TL;DR: The average rate of apparent bone loss in this cross-sectional study was 1% per year from age 45 to 65 years, but about 75% of this decrease occurred in the first decade after the menopause.

TL;DR: It is demonstrated that fluoridated bones dissolve slower than normal bones, deproteinized bones dissolve faster than intact bones and that the initial rate of dissolution of fluoridated bone is always significantly lower than that of normal bone.

TL;DR: There is little to choose between vertebral and forearm density in the diagnosis of osteoporosis but vertebral densitometry is slightly superior to forearm densitometers in describing the severity of osteopsorosis in vertebral fracture patients.

TL;DR: It is concluded that the change in Ca homeostasis in lactating rats is due to the large loss ofCa required for milk production and that the loss of Ca is associated with hyperfunction of the parathyroid gland.

TL;DR: Weight was positively correlated with BMC in both populations, but differences in weight did not explain the differences in bone mass between the blacks and whites, and BMC and age were negatively correlated in both groups.

TL;DR: The results suggest that while a diet containing 0.1% Ca is able to maintain normal growth, bone mineralization is compromised, and Ca presented in a bolus would be utilized as effectively as the same amount of Ca distributed throughout the diet.

TL;DR: In this paper, a sensitive and specific method is proposed to follow bone collagen degradation, which consists of the measurement of galactosyl hydroxylysine (GH) in urine by HPLC.

TL;DR: In this paper, Bone measurements were made in young normal women (n = 125) using single-photon absorptiometry (SPA with 125I) of the radius shaft and ultradistal radius.

TL;DR: A second messenger role for intracellular ionized calcium in the action of bPTH(1-84) in osteoblasts is suggested and a functional role for the COOH-terminal part of the hormone is suggested.

TL;DR: Transiliac bone biopsies were obtained from 72 healthy Norwegians and mean values for osteoid and labelled surfaces as well as bone formation rate were higher in men than in women, while mean cortical thickness and cancellous bone volume decreased with age.

TL;DR: A 34-amino acid synthetic peptide, PTHrP(1-34) was found to be 2-4 times more potent than bovine or human PTH(1 -34) in bioassays promoting the formation of cAMP and plasminogen activity in osteogenic sarcoma cells and activation of adenylate cyclase in chick kidney membranes as mentioned in this paper.

TL;DR: The impairment in stiffness derived from reductions in both bone mass and modulus of elasticity led to an increment in energy absorption by bone and bone tissue which in turn induced a high incidence of comminuted fractures.

TL;DR: In this article, the antigenic phenotype of human osteoclasts was determined using a large number of monoclonal antibodies which react with granulocytes and mononuclear phagocytes.