Showing papers in "Clinical Neurology and Neurosurgery in 2019"

TL;DR: To fully exploit artificial intelligence technologies in the future, more widespread collaboration is advised among medical institutions, clinicians and researchers, to facilitate aligning of data collection protocols, sharing and merging of data sets.

TL;DR: Currently available literature provides data in favor of the use of nTMS motor mapping: its use seems to be associated with a reduced occurrence of postoperative new permanent motor deficits, an increased GTR rate, and a tailored surgical approach compared to standard surgery without using preoperative nT MS mapping.

TL;DR: A systematic review of the intraoperative clinical application of augmented reality in neurosurgery, in studies published during the last five years, can conclude that the neurovascular application is the most frequent type of use for AR in Neurosurgery.

TL;DR: RF is associated with statistically significant higher odds for immediate pain relief and anesthesia and lower risk for post-operative herpes eruption as compared to GR, and patients in the BC group had a statisticallysignificant higher risk to develop post-operatively mastication weakness and diplopia when compared toGR.

TL;DR: Minimally invasive spine surgery, however, might offer comparable outcomes between obese and non-obese patients and further studies are needed to evaluate whether these findings remain valid for morbidly obese (BMI > 40) patients as well.

TL;DR: Logistic regression analyses demonstrated that periventricular WMH, PVS in the basal ganglia, and atrophy were predictors of cognitive impairment in PD, suggesting that PD with PVS can provide novel insights into SVD.

TL;DR: Optimizing spine surgery outcomes in the osteoporotic patient is possible with a thorough preoperative workup, medical management, and a tailoring of the surgical technique.

TL;DR: Aneurysm intervention should be considered when patients over 75 years old do not suffer from sarcopenia, and temporal muscle would indicate premorbid mRS and be potentially useful to decide surgical indication and to predict outcome after aneurysm treatment in the elderly.

TL;DR: Poor sleep efficiency is independently associated with enlarged BG-PVS, suggesting that sleep may influence structural changes in these fluid-filled cavities.

TL;DR: It is suggested that physicians can use Altmetric analysis to identify what the general public actually wants to know about in the real world, while they should also have a critical view of the social media that attracts the public with a stimulating theme rather than a worthy subject.

TL;DR: Treatment of brain metastases with both SRS and an ICI is an effective modality that poses mild risk for developing symptomatic RN when compared to the risk of RN from SRS alone.

TL;DR: MMAE is a feasible technique for cSDH, but the current body of evidence does not yet support its use as a standard treatment and further studies with a higher level of evidence are necessary before MMAE can be formally recommended.

TL;DR: It was confirmed that NRGN levels were significantly higher in CT + patients than CT- patients in the mTBI patient population, and future studies of larger populations and different age groups can help reduce the number of CT scans as a reliable and noninvasive diagnostic tool for evaluating NRGN protein levels in m TBI patients with a low probability of intracranial lesions.

TL;DR: Early PKP could result in better restoration of vertebral body height and reduced rate of subsequent fracture compared to late PKP, and both surgical timings of PKP showed similar outcomes in terms of the VAS and ODI.

TL;DR: It is suggested that HH score and increasing patient age, and not the accumulated co-morbidities at the time of aSAH, better predict outcomes.

TL;DR: The grading of a preoperative MRI scan for lumbar foraminal and lateral recess stenosis may significantly differ between radiologist and surgeon and should be read and grade independently to aid in appropriate patient selection for successful transforaminal endoscopic decompression surgery.

TL;DR: Considering the diagnostic yield benefit contributed by the intraoperative histological smear, it is advocated for its routine use during brain stereotactic biopsies to reduce this negative biopsy rate.

TL;DR: Preoperative NLR was superior to SII in prognostic value of patients with glioblastoma, and Multivariable Cox analysis revealed NLR, adjuvant therapy and age were prognostic factors for overall survival.

TL;DR: Radiomics features of cerebral hematoma on baseline NCCT images showed good performance in predicting HE of SICH.

TL;DR: The factors associated with the risk of falling in iNPH were aging and gait-balance instability, particularly temporal gait variability and dynamic balance dysfunction.

TL;DR: This study indicates that semi-elastic image fusion can be used for retrospective distortion correction of DTI data acquired for image guidance, such as DTI FT as used for a broad range of clinical indications.

TL;DR: Overall, omega-3 fatty acids and vitamin E co-supplementation for 12 weeks in PD patients significantly improved gene expression of TNF-α, PPAR-γ and LDLR, but did not affect IL-1 and IL-8.

TL;DR: DTIT-guided lead placement results in better and more stable tremor control and fewer adverse effects compared to lead placement in the conventional manner because DTIT-guidance allows closer and more consistent placement of leads to the centre of the DRTT than conventional methods.

TL;DR: A comparison of PELD and MIS-TLIF for treating massive lumbar disc herniation revealed that both showed favorable clinical outcomes but had different sets of complications, mainly related to postoperative complications and the satisfaction and recovery rates.

TL;DR: Results point toward differences in social media use based on age or level of training among neurosurgeons at later stages in their career.

TL;DR: The findings suggest that radiomics has broad application prospects in the early screening, accurate diagnosis, grading and staging, treatment and prognosis, and molecular characteristics of CNS diseases, which can improve the capacities to diagnose and predict CNS diseases prognosis through complementing and combining with traditional imaging.

TL;DR: The most recent studies confirmed the overall efficacy of antiplatelet and anticoagulant therapies for CAD patients is equivalent, although patients should be qualified for concrete treatment on the basis of recently characterized clinical features.

TL;DR: It is found that 15% of patients developed delayed hyponatremia and that this occurred most commonly on post-operative day 7, which accounted for more than half of re-admissions after this type of surgery.

TL;DR: T-EVD, when performed according to a previously established perioperative management protocol, resulted in lower infection and CSF leakage rates and is recommended to be preferentially performed when surgeons determine whether a catheter can be removed within 10 days.

TL;DR: Combined analysis of exome, transcriptome, methylome and future approaches for epigenetic aspects in meningiomas may allow researchers to unveil a more comprehensive understanding of tumor progression mechanisms and, consequently, a more personalized clinical approach for patients with meningingioma.