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Showing papers in "Clinics in 2012"


Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: There was a significant prevalence of burnout among the medical students studied and three variables, in particular, were associated with burnout and were directly related to the medical education process.

166 citations


Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: Some features of article titles can help predict the number of article views and citation counts and could be used by authors, reviewers, and editors to maximize the impact of articles in the scientific community.

139 citations


Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: Good postoperative results can be expected in carotid body tumors of Shamblin Class I and II, whereas operations on other carotids body tumors and other head and neck paragangliomas frequently result in deficits of the cranial nerves adjacent to the tumors.

132 citations


Journal ArticleDOI
01 Nov 2012-Clinics
TL;DR: The objective of this review is to highlight the similarities and differences between asthma, chronic obstructive pulmonary disease and bronchiectasis in terms of the risk factors, pathophysiology, symptoms, diagnosis and treatment.

104 citations


Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: Exercise presented similar results when compared with hypnotics; however, prospective studies comparing the effects of exercise with medical and non-medical treatments are warranted before including exercise as a first-line treatment for chronic insomnia are necessary.

102 citations


Journal ArticleDOI
01 Dec 2012-Clinics
TL;DR: Height was the anthropometric variable that most influenced postural balance, both in the whole group and separately for each gender, and was more influenced by anthropometric factors in males than females.

97 citations


Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: HE4 demonstrated the best overall sensitivity for the evaluation of malignant ovarian tumors and the differential diagnosis of endometriosis, and all of the parameters demonstrated increased sensitivity when tumors with low malignancy potential were considered low-risk, which may be used as an acceptable assessment method for referring patients to reference centers.

97 citations


Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: The systematic review of the literature shows that the pediatric anesthesia-related mortality rates in Brazil and in developed countries are similar, whereas the pediatric perioperative mortality rates are higher in Brazil compared with developed countries.

95 citations


Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: Early multidisciplinary intervention appears to be effective for the management of hip fracture, and age, male sex, baseline function, cognitive impairment and previous comorbidities are associated with a higher mortality rate and worse functional recovery.

89 citations


Journal ArticleDOI
01 Sep 2012-Clinics
TL;DR: It is established that patients with cardiac syndrome X and coronary artery disease exhibit higher mean platelet volumes compared to controls, reflecting the presence of subclinical atherosclerosis.

88 citations


Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: The key methods in using cranberries as a preventive measure for lower urinary tract infections are reviewed, including in vitro studies and clinical trials.

Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: Human adipose-derived stem cells retain stem cell characteristics after expansion in culture to passage 4 and serve as a feasible source of cells for cartilage regeneration and examine chondrogenic gene expression after one, two, and three weeks of induction.

Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: Hemorrhage was the main cause of admission and of potentially life-threatening conditions among women admitted to a general intensive care unit during pregnancy or in the postpartum period, suggesting that delays may occur in implementing appropriate obstetrical care.

Journal ArticleDOI
01 Jul 2012-Clinics
TL;DR: The results indicate that the adverse effect of the generated electromagnetic frequency had a negative impact on testicular architecture and enzymatic activity, and indicated the possible role of vitamins C and E in mitigating the oxidative stress imposed on the testes and restoring normality to thetestes.

Journal ArticleDOI
01 Oct 2012-Clinics
TL;DR: The combination of several therapeutic strategies should, at minimum, allow for partial functional recoveries for patients with spinal cord injury, which could improve their quality of life.

Journal ArticleDOI
01 Nov 2012-Clinics
TL;DR: Imaging studies can be of great help in identifying patients prone to develop dysthyroid optic neuropathy and therefore enabling the timely diagnosis and treatment of the condition, avoiding permanent visual loss.

Journal ArticleDOI
01 Dec 2012-Clinics
TL;DR: The results showed that both exercise modalities improved the lipid profile, adiposity and obesity-associated inflammation in rats, suggesting their use as an alternative to control the deleterious effects of a high-fat diet in humans.

Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: It is observed that survival increased approximately 5% for every 100 meters walked in the six-minute walk test, demonstrating that the test is a viable option for evaluating the functional capacity in patients with end-stage renal disease.

Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: Recommendations on the timing of prophylactic thyroidectomy and extent of surgery are based on the classification of rearranged during transfection mutations into risk levels according to genotype-phenotype correlations.

Journal ArticleDOI
01 Jul 2012-Clinics
TL;DR: Although there has been a trend toward stabilization in female breast cancer mortality rates in Brazil, when the mortality rate of each macro-region and state is analyzed individually, considerable inequalities are found, with rate decline or stabilization in states with higher socioeconomic levels and a substantial increase in those with lower socioeconomic levels.

Journal ArticleDOI
01 Jul 2012-Clinics
TL;DR: The aim of this study was to review published data on vancomycin pharmacokinetics in neonates and to provide a critical analysis of the literature to focus on the relevance of therapeutic drug monitoring and on the value of continuous vancomYcin administration in Neonates.

Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: In patients with spinocerebellar ataxia 3, the phenotype was highly pleomorphic, although the most common signs of disease included cerebellarAtaxia (CA), ophthalmoplegia, diplopia, eyelid retraction, facial fasciculation, pyramidal signs, and peripheral neuropathy.

Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: It is suggested that Hypoxia inducible Factor-1 exhibits protective activity in chondrocytes during osteoarthritis because of the involvement of the phosphatidylinositol-3-kinase (PI-3K) pathway in this process.

Journal ArticleDOI
01 Dec 2012-Clinics
TL;DR: In this study, plantar thermography, which predominately considers the small and autonomic fibers that are commonly associated with a sub-clinical condition, proved useful in diagnosing diabetic neuropathy early.

Journal ArticleDOI
01 Aug 2012-Clinics
TL;DR: The relationship between musical auditory stimulation and heart rate variability was described and it was hypothesized that dopamine release in the striatal system induced by pleasurable songs is involved in cardiac autonomic regulation.

Journal ArticleDOI
Jun Zhang1, Hui Qiao1, Zhiyong He1, Yun Wang1, Xuehua Che1, Wei-min Liang1 
01 Oct 2012-Clinics
TL;DR: Monitoring and minimizing pulse pressure variation by 6% hydroxyethyl starch solution (130/0.4) loading during gastrointestinal surgery improves postoperative outcomes and decreases the discharge time of patients who are graded American Society of Anesthesiologists physical status I/II.

Journal ArticleDOI
01 Nov 2012-Clinics
TL;DR: Phosphatidylinositol 3-kinase CA exon 20 mutations are associated with poor survival, and they may be useful biomarkers for identifying breast cancer patients with aggressive tumors and for predicting the response to treatment with PI3K pathway inhibitors.

Journal ArticleDOI
01 Jan 2012-Clinics
TL;DR: Evidence is found that this FoxP3 expression may exert an important influence on several features of tumor aggressiveness and is an independent risk factor for thyroid malignancy.

Journal ArticleDOI
01 Dec 2012-Clinics
TL;DR: Piper betle treatment showed increased antioxidant enzymes activity during aging, and equivocal age-related changes in erythrocyte antioxidant enzyme activity were found when mice were treated with Piper betle, the tocotrienol-rich fraction, and Chlorella vulgaris.

Journal ArticleDOI
01 Sep 2012-Clinics
TL;DR: It is concluded that surgery lasting longer than 120 minutes increases the risk of proximal deep vein thrombosis in patients who underwent total knee arthroplasty.