Showing papers in "European Journal of Ophthalmology in 2020"
TL;DR: The inflammatory reaction and the coagulation alteration present in the patient due to Sars-Cov2 coronavirus may have acted as risk factors for the development of papillophlebitis.
Abstract: Introduction:Papillophlebitis is a rare condition characterized by venous congestion and optic disc edema, which has been suggested to occur as a consequence of inflammation of the retinal veins or...
80 citations
TL;DR: The prevalence of computer vision syndrome symptoms was significantly higher among business students, who reported lower awareness and poor practice measures of computer use recommendations.
Abstract: Purpose:To determine the prevalence of symptoms of computer vision syndrome and to identify its associated factors. The secondary objective was to assess knowledge and practices related to preventi...
73 citations
TL;DR: Micropulse transscleral cyclophotocoagulation appears to be a safe and efficacious treatment for glaucoma and deserves consideration as a primary procedure.
Abstract: Purpose:To describe our clinical experience with the efficacy and safety of micropulse transscleral cyclophotocoagulation as a treatment for glaucoma.Methods:In this retrospective case series, we r...
56 citations
TL;DR: An authoritative, universal, easy-to-use morphologic classification of diabetic maculopathy based on spectral domain optical coherence tomography is presented and can be used for therapeutic and prognostic purposes, as well as for correct evaluation and reproducibility of clinical investigations.
Abstract: Aims:To present an authoritative, universal, easy-to-use morphologic classification of diabetic maculopathy based on spectral domain optical coherence tomography.Methods:The first draft of the proj...
48 citations
TL;DR: A novel surgical technique for sutureless sclera-fixated intraocular lens fixation with good refractive outcomes is described using the newly developed FIL SSF Carlevale IOL in Soleko, Italy.
Abstract: Purpose:The aim of this article is to describe a novel surgical technique for sutureless scleral fixation of an intraocular lens using the newly developed FIL SSF Carlevale IOL (Soleko, Italy).Meth...
46 citations
TL;DR: This real-world study showed that sustained structural and functional improvements can last for up to 3 years with a single FAc implant.
Abstract: Introduction:The Retro-IDEAL (ILUVIEN Implant for chronic DiabEtic MAcuLar edema) study is a retrospective study designed to assess real-world outcomes achieved with the ILUVIEN® (0.19 mg fluocinol...
46 citations
TL;DR: DED is common and can be exacerbated by cataract surgery and ophthalmologists need to assess for pre-existing DED and instigate treatment before surgery; be aware of reduced accuracy of measurements for surgical planning in the presence of DED; limit intra-operative surgical factors damaging to the ocular surface; and consider management to reduce DED post-operatively.
Abstract: AimTo review published literature concerning cataract surgery and dry eye disease (DED).MethodsA search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDL...
45 citations
TL;DR: XEN gel stent, either alone or in combination with phacoemulsification, provided a significant reduction in both intraocular pressure and medical antiglaucoma treatment, but with some safety concerns, in a cohort of patients with open-angle glaucomA (primary or secondary).
Abstract: Purpose:The aim of this study was to compare the efficacy and safety of the XEN45 gel stent implant in patients with primary open-angle glaucoma or secondary open-angle glaucoma.Patients and method...
38 citations
TL;DR: Containment measures in the event of pandemic due to infective agents should be well known by healthcare professionals and promptly applied in order to mitigate the risk of nosocomial transmission and outbreak.
Abstract: IntroductionThe novel coronavirus (SARS-CoV-2) is infecting people and spreading easily from person-to-person. Cases have been detected in most countries worldwide. Italy is one of the most affecte...
33 citations
TL;DR: Optical coherence tomography angiography can detect changes in macular perfusion density in patients with hypertension and high cardiovascular risk and might represent a supportive imaging method in the evaluation of the cardiovascular risk in hypertensive patients.
Abstract: Objective:To evaluate the potential utility of perfusion density measurements to discriminate patients with arterial hypertension by cardiovascular risk category.Methods:In this cross-sectional stu...
32 citations
TL;DR: The results confirm that endoscopic dacryocystorhinostomy can be considered as a valid surgical approach to primary nasolacrimal duct obstruction and revision cases.
Abstract: Introduction:Endoscopic dacryocystorhinostomy is a well-known surgical practice used to treat nasolacrimal duct obstruction and widely considered as a valid alternative to external approaches.Purpo...
TL;DR: SARS-CoV-2 infection appears to have played a role as a possible trigger for intraocular inflammation in this case, and COVID-19 patients reporting visual symptoms should be carefully evaluated in order to obtain adequate ophthalmological management to avoid irreversible visual damage.
Abstract: Introduction:To report the first case of a serpiginous choroiditis presenting after SARS-CoV-2 infection in a previously healthy young woman.Case description:A 41-year-old woman reported blurry vis...
TL;DR: A role for elevated plasma levels of C3a and sC5b-9 in patients with neovascular age-related macular degeneration is suggested, which reinforces the need for more investigation to assess the impact of therapeutic interventions targeted at the complement signaling pathways in age- related macularity degeneration.
Abstract: Purpose:To examine the role of systemic activation of the complement system (assessed by levels of circulating C3a, Ba, and sC5b-9) in patients (n = 122) with advanced age-related macular degenerat...
TL;DR: The new SS-OCTA software served to quantify macular and ONH VD with a reproducibility that was good in the central zones (foveal and papillary, respectively) and moderate in the peripheral zones (parafovesal and peripapillary).
Abstract: Purpose:To assess the reproducibility of swept-source optical coherence tomography angiography (SS-OCTA) for macular and optic nerve head (ONH) vessel density (VD).Methods:Cross-sectional study usi...
TL;DR: Vascular density of choriocapillaris varies with retinal vascular density rather than the structure of choroid using optical coherence tomography angiography, which provides more information about the relationship between retina and choroids.
Abstract: Purpose:To quantify vascular and structural macular variables in healthy eyes and to investigate correlations between these variables and age using optical coherence tomography angiography.Material...
TL;DR: The rotational stability was considerably different among toric intraocular lenses of different manufacturers and the repositioning surgery significantly reduced misalignment in all three groups.
Abstract: Purpose:To compare the incidence of re-orientating surgery to improve misalignment of three models of acrylic toric intraocular lenses: AcrySof toric intraocular lens (Alcon Laboratories, Inc.), TE...
TL;DR: A correlation was found between intraocular lenses’ optical quality and patients’ visual acuity, and contrast sensitivity was very similar between the multifocal and monofocal groups.
Abstract: Objective:To compare visual quality in patients implanted with Tecnis® monofocal (ZCB00) and multifocal (ZMB00) intraocular lenses taking into account their optical quality measured in vitro with a...
TL;DR: Intense regulated pulse light seems a safe treatment procedure for meibomian gland dysfunction, improving tear film quality and reducing symptoms of dry eye.
Abstract: Purpose:To assess the effect of intense regulated pulse light (E-Eye; E-Swin, France) on the treatment of meibomian gland dysfunction.Setting:Health Sciences University, Ankara Numune Training and ...
TL;DR: The clinical features of a rare case of atypical acute retinal necrosis in a Coronavirus Disease 2019 (COVID-19) positive immunosuppressed patient is presented and a number of possible links between the SARS-CoV-2 virus and the unusual ocular presentation of bilateral VZV viral retinitis in this patient are presented.
Abstract: Purpose:To present the clinical features of a rare case of atypical acute retinal necrosis in a Coronavirus Disease 2019 (COVID-19) positive immunosuppressed patient.Methods:Retrospective observati...
TL;DR: Lyme-associated uveitis appears varied and Hyalitis and involvement of the posterior segment and retinal vasculitis seem to be rather frequent, and its prognosis is mainly good, even if inflammation can be resistant or recurring.
Abstract: Background:Clinical presentation of Lyme-associated uveitis is poorly described. We reported here a case series of seven patients with uveitis related to Lyme disease and a review of the literature...
TL;DR: Icare Home tonometry tends to slightly underestimate intraocular pressure compared to Goldmann applanation tonometer, and measurements using rebound self-tonometry could improve the quality of intraocular Pressure data and optimize treatment regimen.
Abstract: Purpose:To evaluate and compare the accuracy of self-measurement of intraocular pressure using Icare Home rebound tonometer with Goldmann applanation tonometer and assess acceptability of self-tono...
TL;DR: At 4 years after the procedure, standard corneal cross-linking offered better anteriorCorneal flattening in the center and periphery, and the two protocols were similarly effective in central cases.
Abstract: Purpose To compare long-term results between accelerated and standard corneal cross-linking protocols in the treatment of progressive keratoconus and compare their effectiveness between central (cone in the central 3 mm) and peripheral (cone beyond 3 mm) cases. Methods In this randomized clinical trial, we compared 31 eyes treated with accelerated corneal cross-linking (18 mW/cm2, 5 min) and 31 eyes treated with standard corneal cross-linking (3 mW/cm2, 30 min), 16 central and 11 peripheral keratoconus in each group. In this report, 4-year changes in vision, refraction, topography, corneal biomechanics, and corneal cell count were evaluated. Results Uncorrected distance visual acuity improvement was better with standard corneal cross-linking (0.19 ± 0.30 logMAR) than accelerated corneal cross-linking (0.08 ± 0.35 logMAR), but the intergroup difference was not statistically significant (p = 0.283). Cylinder and spherical equivalent significantly increased similarly in both groups. Among topographic indices, anterior Kmax-3 mm showed more reduction in standard corneal cross-linking than accelerated corneal cross-linking (1.35 ± 1.39 vs 0.36 ± 1.10 D, p = 0.011). Anterior Kmax-8 mm reduced by 1.50 ± 1.82 and 0.37 ± 1.58 D in the standard corneal cross-linking and accelerated corneal cross-linking groups, respectively (p = 0.029). Compared to 18-month results, none of the indices at 4 years showed any significant intergroup difference (all p > 0.05). In cases with peripheral keratoconus, changes in anterior Kmax-3 mm (+0.03 ± 0.66 vs -1.17 ± 1.15 D, p = 0.012) and anterior Kmax-8 mm (+0.43 ± 1.09 vs -1.57 ± 1.40 D, p = 0.003) were greater with standard corneal cross-linking. In central cases, no significant intergroup difference was observed. Conclusion At 4 years after the procedure, standard corneal cross-linking offered better anterior corneal flattening in the center and periphery. These differences concerned cases of peripheral keratoconus, and the two protocols were similarly effective in central cases. Beyond the 18th month, the two protocols appeared to be similarly effective.
TL;DR: Immunosafe plasma rich in growth factors eye drops for the treatment of patients with ocular graft versus host disease could be safe and effective, showing a high rate of corneal ulcer resolution and dry eye disease control.
Abstract: Purpose:To evaluate the efficacy and safety of plasma rich in growth factors eye drops for the treatment of corneal and ocular surface disorders in patients with graft versus host disease.Methods:T...
TL;DR: Rituximab is a well-tolerated treatment with a good safety profile, but offered limited and partial improvement for active moderate-to-severe Graves’ ophthalmopathy with a long duration of disease.
Abstract: Purpose:Management of Graves’ ophthalmopathy remains challenging. Over the last decade, previous studies have shown promising results for Rituximab in the treatment of Graves’ ophthalmopathy. We pr...
TL;DR: Phacoemulsification tends to induce short-term transitory ocular surface impairment manifesting as both signs and symptoms after cataract surgery, and Superficial punctate keratopathy distribution has a characteristic pattern evolution according to the postoperative time.
Abstract: Purpose:The aim of this study is to evaluate the incidence, natural course, and distribution pattern of superficial punctate keratopathy and describe the changes in signs and symptoms of dry eye af...
TL;DR: In this paper, optical coherence tomography angiography has proven to be a powerful tool in the analysis of diabetic retinopathy common features, including microaneurysms, intra-retinal microvascular abnormalities, or neovascularization.
Abstract: Diabetic retinopathy is a common diabetes complication representing a heavy burden in terms of visual impairment and heath expenditure. Optical coherence tomography angiography is a relatively new imaging method and has proven to be a powerful tool in the analysis of diabetic retinopathy common features, including microaneurysms, intraretinal microvascular abnormalities, or neovascularization, as well as in research field, challenging the gold standard of fluorescein angiography. Many studies underlined the vascular impairment observed through optical coherence tomography angiography and its typical parameters such as vessel length density, foveal avascular zone, and fractal dimension. Choriocapillaris involvement in the pathogenesis of diabetic retinopathy is an interesting point, derived from the analysis of this plexus using optical coherence tomography angiography. In conclusion, optical coherence tomography angiography, which is not free of limitations, such as motion artifacts or segmentation errors, has become an indispensable technique in adding more information to our understanding of diabetic retinopathy.
TL;DR: Micropulsed diode laser was proved to be a safe approach with relative effectiveness in controlling intraocular pressure in children with recurrent glaucoma.
Abstract: Purpose:To evaluate the intermediate-term efficacy and safety of micropulsed diode laser cyclophotocoagulation in recurrent pediatric glaucoma.Patients and Methods:A prospective interventional stud...
TL;DR: Diabetic patients with subclinical diabetic retinopathy feature a larger foveal avascular zone at the superficial capillary plexus compared with controls, as well as relative reduction of the vessel density at the deep capillaryplexus.
Abstract: Purpose:To investigate a subset of diabetic patients without diabetic retinopathy with optical coherence tomography angiography, assessing the differences in macular perfusion between diseased eyes...
TL;DR: The results for true microaneurysm detection indicates it as a useful tool for screening colour fundus images, which proves time saving for counting of microaneuysms to follow Diabetic Retinopathy Grading Criteria.
Abstract: Aim:Fundus image analysis is the basis for the better understanding of retinal diseases which are found due to diabetes. Detection of earlier markers such as microaneurysms that appear in fundus im...
TL;DR: Early switch to Ozurdex in patients who did not adequately respond to anti-vascular endothelial growth factor therapy provided better functional and anatomical outcomes.
Abstract: Purpose:To compare the results of early versus late switch to the dexamethasone intravitreal implant Ozurdex® in patients with diabetic macular edema who had a poor response to vascular endothelial...