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Showing papers in "Experimental Neurology in 1972"


Journal ArticleDOI
TL;DR: Only the impairment produced by the TPA lesion was consistent with a difficulty in the formation of such associations, an interpretation which is strengthened by a consideration of the gross behavioral abnormalities that have been described repeatedly following this same lesion.

844 citations


Journal ArticleDOI
TL;DR: Families of static characteristics of both extensors and flexor were preserved during selective paralysis of gamma efferents by application of novocain to the muscle nerve.

354 citations


Journal ArticleDOI
TL;DR: The stimulus intensities and frequencies of shocks producing progressively more intense second pain and late flexion reflexes are consistent with previously observed increases in dorsal horn responses to iterative C fiber stimulation.

280 citations


Journal ArticleDOI
TL;DR: In this paper, the authors found that the receptive fields of lateral geniculate (LGN) and striate cortex cells were essentially normal except for cortical ocular dominance patterns.

234 citations


Journal ArticleDOI
TL;DR: It is suggested that vinblastine and colchicine elicit these denervation-like changes by interfering with axoplasmic flow and subsequently with the release of some neural factor or factors other than the transmitter itself.

224 citations


Journal ArticleDOI
TL;DR: Ipsilateral horizontal eye movements were induced in monkeys at short latency by electrical stimulation of the paramedian zone of the pontine reticular formation (PPRF) and activity induced by the stimulating pulses appeared to have been mathematically integrated.

216 citations


Journal ArticleDOI
TL;DR: The results are interpreted to mean that in newt tail regeneration, as in that of the lizard, the ependyma forms a pathway to guide regenerating cord fibers caudally.

191 citations


Journal ArticleDOI
TL;DR: The effects of cooling the visual cortex upon unimodal and multimodal unit response properties were investigated and were found to selectively depress responsiveness to visual stimuli while responsiveness to auditory and somatic stimuli remained unaltered.

189 citations


Journal ArticleDOI
TL;DR: The path followed by spontaneous seizure activity in spreading to other structures is a feature peculiar to each individual and can be established for that patient by this method.

137 citations


Journal ArticleDOI
TL;DR: Electrical stimulation was applied through a concentric bipolar electrode in the area of entry of the medial lemniscus into the thalamus to produce antidromic volleys in axons of spinothalamic tract neurons in cats to determine the location of antidromically activated cells.

136 citations


Journal ArticleDOI
TL;DR: Electrocortical maturation of both evoked responses was characterized by wave-form, amplitude, and latency changes consistent with the structural development of the neocortex and corpus callosum.

Journal ArticleDOI
TL;DR: Variation of pulse patterns indicate that the frequency specificity of internal laryngeal nerve stimulation is maintained within the brain stem pathways evoking the swallowing, suggesting that the optimum frequencies of electrical stimulation simulate the integrative input of fibers of the nerve and determine the motor response and synergy of active muscles.

Journal ArticleDOI
TL;DR: Prenatal development of muscle fibers was examined histochemically in the fetal lamb from 50–145 days of gestation, and it seems likely that the quantity of muscle contraction is not the major determining factor for the differentiation of these fiber types.

Journal ArticleDOI
TL;DR: The general cellular distribution pattern of mercury seems to correspond to the anatomical localization of the pathological changes in various parts of the nervous system after mercury intoxication.

Journal ArticleDOI
TL;DR: Findings indicate that the afterdischarges elicited in vitro are akin to the interictal paroxysmal discharges in the C1-deficient medium.

Journal ArticleDOI
TL;DR: Oxytocin excited the majority of PV units which could be activated antidromically by stimulation of the neural lobe but failed to excite PV neurons which could not be identified in this way and cells in the SO nucleus, cortex, and thalamus.

Journal ArticleDOI
TL;DR: In this article, the effect of stereotaxic lesions of the ventral anterior thalamus or the adjacent inferior thalamic peduncle on experimental models of focal cortical epilepsy was studied.

Journal ArticleDOI
TL;DR: It is concluded that pattern recognition mechanisms, rather than a strict form of place specificity, control the reformation of optic nerve connections in adult goldfish.

Journal ArticleDOI
TL;DR: No dissociation could be demonstrated between the pathway mediating spontaneous inspiration and that serving the inspiratory response to stimulation of the medial reticular formation in the medulla, and the descending projection serving the abdominal muscle component of the cough response was separate from that serving spontaneous inspiration, and lay just ventral to the ventral horn.

Journal ArticleDOI
TL;DR: It is concluded that, despite a quantitative deficiency in the mass of regenerating muscle, those fibers which are present rapidly approach the normal condition in functional as well as morphological characteristics.

Journal ArticleDOI
TL;DR: It is concluded that the histochemical method for AM-ATPase does not necessarily reveal the level of enzymatic activity and that erroneous conclusions may result from the quantitative interpretation of histochemical observations.

Journal ArticleDOI
TL;DR: Structural analysis of the nucleus reticularis thalami in the adult cat, using variations of the rapid Golgi method, reveals significant differences between anterior pole and dorsolateral portions ofthe nucleus, suggesting the possibility of more than one functional role for this nuclear complex.

Journal ArticleDOI
TL;DR: Dgenerated axons have been traced to the dorsal cochlear nucleus with the Nauta method in cats, and the pattern of preterminal degeneration after short survivals is typical of both axosomatic and axodendritic endings on small and large cells in this nucleus, including the fusiform cells and giant cells.

Journal ArticleDOI
TL;DR: It is concluded that paradoxical sleep, which is absent in the most primitive mammal (echidna), has evolved independently in birds and therian mammals.

Journal ArticleDOI
TL;DR: Results suggest that higher concentrations of local anesthetic agents are more generally histotoxic than previously thought, and preferential destruction of red- or white-type muscle fibers was observed after many of the agents.

Journal ArticleDOI
TL;DR: The alteration in the appearance of the fluorescent fibers in the dorsal lateral geniculate nucleus after visual cortex ablation is interpreted as an increase in the adrenergic innervation of this nucleus produced by denervation, further evidence of the plasticity of central monoamine neuron systems.

Journal ArticleDOI
TL;DR: The results suggest that neurons in the central auditory pathway of primed mice are overreactive to afferent input, thus supporting a recent hypothesis on the effects of priming for audiogenic seizure.

Journal ArticleDOI
TL;DR: Organotypic cultures provide a reliable model system for studies of some of the mechanisms underlying muscle regeneration and the restoration of functional neuromuscular relations which may be difficult to analyze in situ.

Journal ArticleDOI
D.P. Cain1, D. Bindra1
TL;DR: Results are consistent with the general idea that the amygdala has some role in the processing of odors that are important in many species-typical actions, however, no support was found for the hypothesis that certain amygdala units respond exclusively to particular natural odors.

Journal ArticleDOI
TL;DR: From autoradiograms of the tectum it was found that the increase in radioactivity signaling the arrival of the slow component could not be detected in the synaptic endings of the optic fibers where the fast component accumulated.