Showing papers in "Hearing Research in 1984"

TL;DR: Hair cells of the guinea pig cochlea were preserved by fixing in glutaraldehyde without the use of osmium to explain the V shape of the rows of stereocilia on outer hair cells, and a membrane roughness was seen, particularly pronounced in the region of the stereocilium which gives rise to the cross-links.

TL;DR: The correlations between structural and functional changes suggest that a normal tuning-curve tip requires that the stereocilia on both the IHCs and OHCs (especially those from the first row) be normal.

TL;DR: Intact and destroyed cat cochleae were electrically stimulated through round window electrodes and neuronal responses to any electric stimulus differed considerably from the responses to corresponding acoustic stimuli.

TL;DR: Single fiber recordings from the electrically stimulated auditory nerve yield post-stimulus time (PST) histograms demonstrating several response patterns, postulated that threshold excitation of normal auditory neurons occurs on the dendritic processes.

TL;DR: Results indicate that as intensity increases, the auditory nerve fiber responds more vigorously and with greater time resolution to the onset of tonal stimuli.

TL;DR: The frequency selectivity of the acoustic DP generation mechanism shows a close association with the transduction mechanism, and the results show the acoustic response to be suppressible in a similar, frequency-dependent manner in both species.

TL;DR: The application of intracellular labeling techniques to noise-exposed ears makes it possible to accurately correlate fiber populations showing SR abnormalities with the cochlear locations from which these responses originate, revealing that a decrease in the mean rates of spontaneous discharge is typically associated with selective loss of the tallest row of stereocilia from the inner hair cells.

TL;DR: Furosemide administration produced reversible, dose-related decreases in the EP which were accompanied by threshold elevations and alterations in the tuning curves of auditory nerve fibers, with higher CF fibers showing larger threshold shifts than lower CF fibers.

TL;DR: In this paper, single afferent and efferent neurones in the guinea pig spiral ganglion were injected with horseradish peroxidase and recovered in subsequent histological processing and traced from the injection site to their final termination in the organ of Corti.

TL;DR: Results of single-unit labeling in a Noise-induced threshold shift case suggest that the selective attenuation of component I is associated with selective loss of the tallest row of stereocilia on the inner hair cells (IHCs), and it is suggested that components I and II are normally generated through an interaction between the outer hair cells and the tall row of IHC stereOCilia.

TL;DR: The number of sensory hair cells on the saccular sensory epithelium in specimens of the cichlid fish Astronotus ocellatus and the increase in both length and weight of the animals studied were statistically correlated and the average ratio of hair cells to afferent fibers increases from about 30:1 in the smallest fish to over 300: 1 in the largest animals.

TL;DR: Although an increase in hair-bundle length with distance from the stapes accounts for some of the observed stiffness decrease, the major decrease is due to a increase in compliance of the sensory-hair attachment to the hair-cell surface.

TL;DR: Changes in the surface morphology of the organ of Corti in the chinchilla were studied following exposure to blast waves at 160 dB peak SPL and a spectrum of ciliary changes was observed that differ somewhat from those commonly reported following continuous noise exposure.

TL;DR: The N1 peak exhibits anomalous refractory behavior which can be identified in the electrically evoked auditory brainstem response (EABR), which may be useful diagnostically in assessing the extent of dendrite degeneration in cochlear implant candidates and users.

TL;DR: It is suggested that throughout the adult CM frequency range cochlear hair cell function develops simultaneously, similar to how in the Mongolian gerbil.

TL;DR: Iontophoretic injections of horseradish peroxidase were used to label single auditory-nerve fibers in cats with permanent, noise-induced or drug-induced threshold shifts to estimate the degree to which the characteristic frequency of a neuron shifts as its threshold shifts in cases of chronic cochlear pathology.

TL;DR: The tuning properties of the basilar membrane and the presence of acoustic emissions from the cochlea suggest that an energy consuming, mechanically active cochlear amplifier exists, and these properties are such that resonance of the stereocilia of the OHCs could form part of the coChlea amplifier, at least in man.

TL;DR: The cytoarchitecture, fiber architecture, and neuronal organization of the adult human medial geniculate body were studied in Nissl, Golgi, and other preparations and three divisions, comparable to those in other mammals, were described.

TL;DR: Modulation of the high frequency motion of the cochlear partition in the first turn of the guinea pig cochlea was in synchrony with the displacement caused by the low frequency tone.

TL;DR: The spatio-temporal distributions of these components are very similar to those obtained in other neocortical areas and thus corroborate the hypothesis that afferent activity is relayed very similarly in all sensory areas of neocortex.

TL;DR: In this paper, the authors used a model condition for sensorineural hearing loss, where the hearing loss is not asymmetrically distributed toward the high frequency region, as it typically is with mild sensorinaural deafness, and large individual differences in the amount of temporary hearing loss induced by fixed doses of aspirin.

TL;DR: It is concluded that GAD-like immunoreactivity is present in a subpopulation of cochlear efferents that contains elements from both the medial and the lateral olivocochlear system and future studies are needed to determine whether this subpopulation is GABA-ergic and/or cholinergic.

TL;DR: Close parallels have been found between the behaviour of the distortion product 2f1-f2 measured acoustically in the meatus and the CMDP measured in the gross cochlear electrical response from the round window during two-tone stimulation.

TL;DR: It is concluded that at stimulus levels below 90 dB SPL the ANN is almost entirely neural in origin, while the FFR is certainly largely neural, that is, that both responses are quite distinct from the CM.

TL;DR: Mild hearing loss in four cats produced a marked alteration in certain characteristics of the central auditory mechanisms, and the magnitudes of the decreases in stimulation threshold and background activity proved not to be highly correlated.

TL;DR: Data is presented on interactions among SOAEs in ears with multipleSOAEs, including: intermodulation distortion products, mutual suppression, and noncontiguous-linked SOAE's which apparently share energy between two quasi-stable states.

TL;DR: Results from ears possessing SOAEs support a hypothesis that a punctate loss of the organ of Corti (OC) may facilitate the occurrence of an SOAE, and provide strong, though indirect support for active and nonlinear models in interpreting cochlear biomechanical phenomena.

TL;DR: The findings agree with previous observations with the Golgi method showing that entirely separate populations of spiral ganglion cells innervate the inner and outer hair cells.

TL;DR: The ALSR provides a good representation of stimulus spectrum, even in the presence of background noise, and from the harmonic structure of the ALSR is able to extract the stimulus pitch frequency.