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Showing papers in "International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes in 1987"



Journal ArticleDOI
TL;DR: Paired-label experiments with goat IgG labeled with 125I using ATE and 131I using Iodogen demonstrated that use of the ATE reagent for protein labeling significantly reduced the thyroid uptake of radioiodine.

172 citations


Journal ArticleDOI
TL;DR: In this article, the performance of an analytical peak shape function for fitting peaks in alpha-particle spectra has been examined using carefully measured spectra of 234U, 241Am and plutonium.

147 citations


Journal ArticleDOI
TL;DR: The main biological and practical aspects of the micronucleus assay are outlined and its potential to serve as a rapid and reliable measure of radiation overexposures and hypersensitivities is discussed.

110 citations


Journal ArticleDOI
TL;DR: In this paper, a general equation is derived, which allows one to compute unbiased values of nitrogen uptake rates in the presence of a single nitrogen compound, which is due to a characteristic of stable isotope techniques where, unlike radioactive techniques, a ratio of isotopic abundances is measured.

85 citations


Journal ArticleDOI
TL;DR: An EEC task group representing four European laboratories routinely using 15O in PET studies was set up to review the current practice of 15O production purification and quality control of the clinically useful products.

79 citations


Journal ArticleDOI
TL;DR: The synthesis of no-carrier-added [1-11C]amino acids from [ 11C]HCN via [11C].aminonitriles was successfully carried out, and this method is suitable for automation of [ 1-11Csamino acid production.

74 citations


Journal ArticleDOI
TL;DR: In this article, chlorination of [11C]methane to carbon tetrachloride by catalysis followed by catalytic oxidation to [11c]phosgene, gives a three fold improvement in specific activity.

68 citations


Journal ArticleDOI
TL;DR: A new technique for analysis of lithium and boron at ultratrace concentrations (less than 10(-8)g g-1) is described, to provide a realistic base for other workers to judge the reliability of the method.

57 citations


Journal ArticleDOI
TL;DR: In this article, a new 99m Tc generator for the preparation of radiopharmaceuticals has been developed, whose elution characteristics and chemical stability merit its consideration as a replacement for present generators.

56 citations


Journal ArticleDOI
TL;DR: L-p-[18F]fluorophenylalanine was designed as a potential marker for probing protein synthesis in the human brain by positron emission tomography and has been synthesized using nucleophilic displacement of the activated nitro group of p-nitrobenzaldehyde by NCA 18F- obtained from the 18O (p, n) reaction on enriched water.

Journal ArticleDOI
TL;DR: The radiochemical separation of 66Ga from the irradiated copper target as well as from the other radionuclides formed is described and the intended use of the 66Ga produced is to label monoclonal antibodies for PET scanning.


Journal ArticleDOI
Ren Iwata1, Tatsuo Ido1, Frank Brady1, Toshihiro Takahashi1, Akira Ujiie1 
TL;DR: In this article, a [18F]fluoride was produced via the 18O(p,n)18F reaction with a circulating 20% enriched [18O]water target.

Journal ArticleDOI
TL;DR: A simple method for the quantitation of 14C-whole-body autoradiograms by comparative densitometry is described and is demonstrated to be simple, accurate, reproducible and precise.

Journal ArticleDOI
TL;DR: In this article, the exact and high-order approximate formulae were derived by Smith based on the theory of Cox and Isham for the case of equal dead times and for one dead time being twice the other.

Journal ArticleDOI
TL;DR: In this paper, the production of 82 Sr from proton irradiation of natural RbCl targets has been investigated, using ion exchange on Chelex 100 with an average recovery of 83%.

Journal ArticleDOI
TL;DR: The validity of the radiosynthesis was confirmed by a parallel synthesis of [13C]melatonin and examination of the product by 13C-NMR spectroscopy and mass spectrometry and Radiochemical and chemical purity were demonstrated by HPLC and TLC.

Journal ArticleDOI
TL;DR: It is shown that zirconium molybdate gel, prepared from neutron irradiatedmolybdenum oxide with 99Mo specific activities between 4.3 and 13.5 GBq g-1 is sufficiently stable for use as a matrix in preparation of high activity 99mTc generators.

Journal ArticleDOI
TL;DR: Tissue-free water tritium (TFWTWT) and tissue-bound TBT (TBT) were analyzed in pine needles collected at 21 locations of the general environment in Japan.

Journal ArticleDOI
TL;DR: Results indicate that the two 99Tc (NEP-DADT) complexes are syn and anti isomers (i.e. one isomer has the N-piperdinylethyl side chain located syn to the technetium oxo core while the other has this side chain Located anti to the technology core).

Journal ArticleDOI
TL;DR: In this paper, a liquid-scintillation spectrometer was used to count alpha and beta particles in liquid scintillation using pulse shape analysis, and the resulting very low instrument alpha particle background allowed detection of alpha particle activities below 1 mBq per sample in 100 minutes.

Journal ArticleDOI
TL;DR: In this article, Cerenkov counting with a high-discriminator setting provided accurate quantitation without interference of potential contaminants which were either removed by separation or discriminated against by counting procedure.

Journal ArticleDOI
TL;DR: The production and radiochemical purification of no-carrier-added (NCA) bismuth isotopes was studied to provide aqueous solutions of chemically and biologically useful amounts of NCA 206,205Bi for measuring tissue and subcellular-distributions and for studies covering several chemical aspects of the development of Pb/Bi radiotherapeutic agents.

Journal ArticleDOI
TL;DR: Palladium-109 and holmium-166 are radionuclides with nuclear, physical and chemical characteristics appropriate for therapeutic purposes and their radiation absorbed doses are calculated and compared with currently used radions in synoviotherapy.

Journal ArticleDOI
TL;DR: In this article, a tentative reaction scheme is given for the degradation of perchloroethylene to chloride ions in air-saturated reagent grade water and at concentrations between 5 and 10 ppm.

Journal ArticleDOI
TL;DR: In this article, the contents of fallout 137 Cs in soil profiles were used to estimate erosion losses from steeply sloping croplands in Korea, and the cropland sites had been cultivated for periods ranging from 5 to more than 80 y (median 10 y).

Journal ArticleDOI
TL;DR: In this article, the reaction of aryldimethylsulfonium methylsulfates with tetra-n-butylammonium [18F]fluoride in acetonitrile or dimethyl sulfoxide has been studied.

Journal ArticleDOI
TL;DR: A method is described for the preparation of [11C]buprenorphine in high specific activity, based on the reaction of N-(de-cyclopropylmethyl)bup Renorphine with "no carrier added" followed by reduction with lithium aluminium hydride.

Journal ArticleDOI
TL;DR: Samarium-153 has been standardized by 4 pi beta liquid-scintillation counting, with an uncertainty of 0.4%, and the half life was found to be 46.27 +/- 0.02 h.